The effect of a nuclear localization sequence on transfection efficacy of genes delivered by cobalt(II)-polybenzimidazole complexes

Biomaterials

Volumn 33, Issue 31, 2012, Pages 7884-7894

  Yin, Jun ^a   Meng, Xianggao ^a   Zhang, Shibing ^a   Zhang, Dan ^a   Wang, Li ^a   Liu, Changlin ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

Co(II) polybenzimidazole complex; NLS; Nonviral gene carrier; Transfection

Indexed keywords

CANCER CELL LINES; CELL LINES; CELL VIABILITY; CELL-PENETRATING PEPTIDE; CO COMPLEXES; DELIVERY SYSTEMS; DNA CONDENSATES; DNA CONDENSATION; ELECTROSTATIC COMPLEXES; GENE CARRIER; GENE-DELIVERY SYSTEMS; IN-VITRO; LUCIFERASE ACTIVITIES; NLS; NUCLEAR LOCALIZATION SEQUENCES; POLYBENZIMIDAZOLE; POSITIVE CHARGES; POSITIVELY CHARGED PEPTIDES; TRANS-GENES; TRANSFECTION;

CELL CULTURE; COBALT; COBALT COMPOUNDS; DNA; DNA SEQUENCES; GENE EXPRESSION; METAL COMPLEXES; NANOPARTICLES; PEPTIDES; VEHICULAR TUNNELS;

MOLECULAR BIOLOGY;

COBALT COMPLEX; DNA; IMIDAZOLE DERIVATIVE; NANOPARTICLE;

ARTICLE; BINDING KINETICS; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DETERMINATION; DNA STRUCTURE; ENZYME ACTIVITY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; MOLECULAR ELECTRONICS; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SURFACE CHARGE; ZETA POTENTIAL;

AMINO ACID SEQUENCE; ANIMALS; BENZIMIDAZOLES; CELL DEATH; CELL LINE; CELL SURVIVAL; COBALT; DNA; ENDOCYTOSIS; GREEN FLUORESCENT PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; LUCIFERASES; MICROSCOPY, FLUORESCENCE; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNALS; PARTICLE SIZE; STATIC ELECTRICITY; TRANSFECTION; TRANSGENES;

EID: 84865184530     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.017     Document Type: Article

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