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Volumn 16, Issue 2, 2012, Pages 84-89

Recognition of betaine as an inhibitor of lipopolysaccharide- induced nitric oxide production in activated microglial cells

Author keywords

Betaine; Lipopolysaccharides (LPS); Microglia; Nitric oxide (NO)

Indexed keywords

BETAINE; LIPOPOLYSACCHARIDE; NITRIC OXIDE;

EID: 84865183912     PISSN: 1028852X     EISSN: None     Source Type: Journal    
DOI: 10.6091/IBJ.1012.2012     Document Type: Article
Times cited : (33)

References (32)
  • 1
    • 33847644521 scopus 로고    scopus 로고
    • Glial cells more than support cells?
    • He F, Sun YE. Glial cells more than support cells? Int J Biochem Cell Biol.2007;39(4):661-665.
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.4 , pp. 661-665
    • He, F.1    Sun, Y.E.2
  • 2
    • 12844280566 scopus 로고    scopus 로고
    • Characterization of new microglia-like cells obtained from neonatal rat brain
    • Kim OS, Lee CS, Kim HY, Joe E-h, Jou I. Characterization of new microglia-like cells obtained from neonatal rat brain. Biochem Biophys Res Commun.2005;328(1):281-287.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.1 , pp. 281-287
    • Kim, O.S.1    Lee, C.S.2    Kim, H.Y.3    Joe, E.-H.4    Jou, I.5
  • 4
    • 0029270425 scopus 로고
    • Microglia, the first line of defense in brain pathologies
    • Kreutzberg GW. Microglia, the first line of defense in brain pathologies. Arzneimittel-Forschung. 1995;45: 357-360.
    • (1995) Arzneimittel-Forschung , vol.45 , pp. 357-360
    • Kreutzberg, G.W.1
  • 5
    • 77950826971 scopus 로고    scopus 로고
    • Microglia in the aging brain: Relevance to neurodegeneration
    • Mar
    • Luo XG, Ding JQ, Chen SD. Microglia in the aging brain: relevance to neurodegeneration. Mol Neurodegener. 2010 Mar;5:12.
    • (2010) Mol Neurodegener , vol.5 , pp. 12
    • Luo, X.G.1    Ding, J.Q.2    Chen, S.D.3
  • 7
    • 77954959261 scopus 로고    scopus 로고
    • Pinoresinol from the fruits of Forsythia koreana inhibits inflammatory responses in LPS-activated microglia
    • Aug
    • Jung HW, Mahesh R, Lee JG, Lee SH, Kim YS, Park YK. Pinoresinol from the fruits of Forsythia koreana inhibits inflammatory responses in LPS-activated microglia. Neurosci Lett. 2010 Aug;480(3):215-220.
    • (2010) Neurosci Lett , vol.480 , Issue.3 , pp. 215-220
    • Jung, H.W.1    Mahesh, R.2    Lee, J.G.3    Lee, S.H.4    Kim, Y.S.5    Park, Y.K.6
  • 8
    • 24644450065 scopus 로고    scopus 로고
    • Rabies virus-induced activation of mitogen-activated protein kinase and NF-κB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia
    • Sep
    • Nakamichi K, Saiki M, Sawada M, Takayama-Ito M, Yamamuro Y, Morimoto K, et al. Rabies virus-induced activation of mitogen-activated protein kinase and NF-κB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia. J Virol. 2005 Sep; 79(18):11801-11812.
    • (2005) J Virol , vol.79 , Issue.18 , pp. 11801-11812
    • Nakamichi, K.1    Saiki, M.2    Sawada, M.3    Takayama-Ito, M.4    Yamamuro, Y.5    Morimoto, K.6
  • 9
    • 0035152836 scopus 로고    scopus 로고
    • Immune function of microglia
    • Nov
    • Aloisi F. Immune function of microglia. Glia.2001 Nov;36(2): 165-179.
    • (2001) Glia , vol.36 , Issue.2 , pp. 165-179
    • Aloisi, F.1
  • 10
    • 77649205429 scopus 로고    scopus 로고
    • Identification of KT-15073 as an inhibitor of lipopolysaccharide-induced microglial activation
    • Ock J, Hong SH, Suk K. Identification of KT-15073 as an inhibitor of lipopolysaccharide-induced microglial activation. Biol Pharm Bull.2010;33(3):461-467.
    • (2010) Biol Pharm Bull , vol.33 , Issue.3 , pp. 461-467
    • Ock, J.1    Hong, S.H.2    Suk, K.3
  • 11
    • 33747463996 scopus 로고    scopus 로고
    • Microglia biology in health and disease
    • Jun
    • Garden GA, Möller T. Microglia biology in health and disease. J Neuroimmune Pharmacol.2006 Jun; 1(2): 127-137.
    • (2006) J Neuroimmune Pharmacol , vol.1 , Issue.2 , pp. 127-137
    • Garden, G.A.1    Möller, T.2
  • 12
    • 0033362157 scopus 로고    scopus 로고
    • Microglia and the immune pathology of Alzheimer disease
    • Jul
    • Giulian D. Microglia and the immune pathology of Alzheimer disease. Am J Hum Genet. 1999 Jul;65(1):13-18.
    • (1999) Am J Hum Genet , vol.65 , Issue.1 , pp. 13-18
    • Giulian, D.1
  • 13
    • 34548490122 scopus 로고    scopus 로고
    • Induction of astrogliosis by activated microglia is associated with a down-regulation of metabotropic glutamate receptor 5
    • Sep
    • Tilleux S, Berger J, Hermans E. Induction of astrogliosis by activated microglia is associated with a down-regulation of metabotropic glutamate receptor 5. J Neuroimmunol. 2007 Sep;189(1/2):23-30.
    • (2007) J Neuroimmunol , vol.189 , Issue.1-2 , pp. 23-30
    • Tilleux, S.1    Berger, J.2    Hermans, E.3
  • 14
    • 34347391508 scopus 로고    scopus 로고
    • Mcroglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype
    • Aug
    • Flode AM, Combs CK. Mcroglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype. J Neurosci Methods.2007 Aug;164(2):218-224.
    • (2007) J Neurosci Methods , vol.164 , Issue.2 , pp. 218-224
    • Flode, A.M.1    Combs, C.K.2
  • 15
    • 34547127632 scopus 로고    scopus 로고
    • Neuroprotective role of the innate immune system by microglia
    • Jul
    • Glezer I, Simard AR, Rivest S. Neuroprotective role of the innate immune system by microglia. Neuroscience. 2007 Jul; 147(4):867-883.
    • (2007) Neuroscience , vol.147 , Issue.4 , pp. 867-883
    • Glezer, I.1    Simard, A.R.2    Rivest, S.3
  • 16
    • 67649394108 scopus 로고    scopus 로고
    • Lipopolysaccharide extends the lifespan of mouse primary-cultured microglia
    • Jul
    • Kaneko YS, Nakashima A, Mori K, Nagatsu T, Nagatsu I, Ota A. Lipopolysaccharide extends the lifespan of mouse primary-cultured microglia. Brain Res. 2009 Jul; 1279:9-20.
    • (2009) Brain Res , vol.1279 , pp. 9-20
    • Kaneko, Y.S.1    Nakashima, A.2    Mori, K.3    Nagatsu, T.4    Nagatsu, I.5    Ota, A.6
  • 17
    • 34250769329 scopus 로고    scopus 로고
    • S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfolding
    • Jul
    • Nakamura T, Lipton SA. S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfolding. Cell Death and Differ.2007 Jul; 14(7): 1305-1314.
    • (2007) Cell Death and Differ , vol.14 , Issue.7 , pp. 1305-1314
    • Nakamura, T.1    Lipton, S.A.2
  • 18
    • 33745039466 scopus 로고    scopus 로고
    • Nitric oxide, cell bioenergetics and neurodegeneration
    • Jun
    • Moncada S, Bolaños JP. Nitric oxide, cell bioenergetics and neurodegeneration. J Neurochem.2006 Jun;97 (6): 1676-1689.
    • (2006) J Neurochem , vol.97 , Issue.6 , pp. 1676-1689
    • Moncada, S.1    Bolaños, J.P.2
  • 19
    • 33646747001 scopus 로고    scopus 로고
    • Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia
    • May
    • Obeid R, Herrmann W. Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia. FEBS Lett.2006 May;580(13): 2994-3005.
    • (2006) FEBS Lett , vol.580 , Issue.13 , pp. 2994-3005
    • Obeid, R.1    Herrmann, W.2
  • 21
    • 4544358286 scopus 로고    scopus 로고
    • Betaine in human nutrition
    • Sep
    • Craig SA. Betaine in human nutrition. Am J Clin Nutr.2004 Sep;80(3):539-549.
    • (2004) Am J Clin Nutr , vol.80 , Issue.3 , pp. 539-549
    • Craig, S.A.1
  • 22
    • 36849014318 scopus 로고    scopus 로고
    • Betaine modulates age-related NF-κB by thiol-enhancing action
    • Dec
    • Go EK, Jung KJ, Kin JM, Lim H, Yu BP, Chung HY. Betaine modulates age-related NF-κB by thiol-enhancing action. Biol Pharm Bull. 2007 Dec;30 (12):2244-2249.
    • (2007) Biol Pharm Bull , vol.30 , Issue.12 , pp. 2244-2249
    • Go, E.K.1    Jung, K.J.2    Kin, J.M.3    Lim, H.4    Yu, B.P.5    Chung, H.Y.6
  • 23
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Aug
    • Giulian D, Baker TJ. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci. 1986 Aug; 6(8):2163-2178.
    • (1986) J Neurosci , vol.6 , Issue.8 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 24
    • 55049136520 scopus 로고    scopus 로고
    • Neuroinflammation and microglia: Considerations and approaches for neurotoxicity assessment
    • Oct
    • Harry GJ, Kraft AD. Neuroinflammation and microglia: Considerations and approaches for neurotoxicity assessment. Expert Opin Drug Metab Toxicol. 2008 Oct;4(10):1265-1277.
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , Issue.10 , pp. 1265-1277
    • Harry, G.J.1    Kraft, A.D.2
  • 25
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: An essential link between degeneration and regeneration
    • Neumann H, Kotter MR, Franklin RJM. Debris clearance by microglia: An essential link between degeneration and regeneration. Brain.2009;132(2):288-295.
    • (2009) Brain , vol.132 , Issue.2 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.M.3
  • 27
    • 33646395680 scopus 로고    scopus 로고
    • Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide
    • Apr
    • Gibbons HM, Dragunow M. Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide. Brain Res.2006 Apr;1084(1):1-15.
    • (2006) Brain Res , vol.1084 , Issue.1 , pp. 1-15
    • Gibbons, H.M.1    Dragunow, M.2
  • 28
    • 27744467465 scopus 로고    scopus 로고
    • Betaine suppresses proinflammatory signaling during aging: The involvement of nuclear factor-κB via nuclear factor-inducing kinase/lκB kinase and mitogen-activated protein kinases
    • Oct
    • Go EK, Jung KJ, Kim JY, Yu BP, Chung HY. Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-κB via nuclear factor-inducing kinase/lκB kinase and mitogen-activated protein kinases. J Gerontol A Biol Sci Med Sci. 2005 Oct;60(10):1252-1264.
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , Issue.10 , pp. 1252-1264
    • Go, E.K.1    Jung, K.J.2    Kim, J.Y.3    Yu, B.P.4    Chung, H.Y.5
  • 29
    • 67650809239 scopus 로고    scopus 로고
    • S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters
    • Jul
    • Lin HC, Hsieh HM, Chen YH, Hu ML. S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters. Neuro Toxicol. 2009 Jul; 30(4):622-627.
    • (2009) Neuro Toxicol , vol.30 , Issue.4 , pp. 622-627
    • Lin, H.C.1    Hsieh, H.M.2    Chen, Y.H.3    Hu, M.L.4
  • 30
    • 3242765241 scopus 로고    scopus 로고
    • Changes in GABA Transporters in the rat hippocampus after kainate-induced neuronal injury: Decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1
    • Aug
    • Zhu XM, Ong WY. Changes in GABA Transporters in the rat hippocampus after kainate-induced neuronal injury: decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1. J Neurosci Res. 2004 Aug; 77(3):402-409.
    • (2004) J Neurosci Res , vol.77 , Issue.3 , pp. 402-409
    • Zhu, X.M.1    Ong, W.Y.2
  • 31
    • 4644301096 scopus 로고    scopus 로고
    • Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy
    • Oct
    • Schousboe A, Larsson OM, Sarup A, White HS. Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy. Eur J Pharmacol. 2004 Oct;500(1/3):281-287.
    • (2004) Eur J Pharmacol , vol.500 , Issue.1-3 , pp. 281-287
    • Schousboe, A.1    Larsson, O.M.2    Sarup, A.3    White, H.S.4
  • 32
    • 26244461268 scopus 로고    scopus 로고
    • Effect of hyperosmotic conditions on the expression of the betaine-GABA-transporter (BGT-1) in cultured mouse astrocytes
    • Jun-Jul
    • Olsen M, Sarup A, Larsson OM, Schousboe A. Effect of hyperosmotic conditions on the expression of the betaine-GABA-transporter (BGT-1) in cultured mouse astrocytes. Neurochem Res. 2005 Jun-Jul;30(6/7):855-865.
    • (2005) Neurochem Res , vol.30 , Issue.6-7 , pp. 855-865
    • Olsen, M.1    Sarup, A.2    Larsson, O.M.3    Schousboe, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.