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Volumn 59, Issue 117, 2012, Pages 1529-1536

Bear bile inhibits the immunosuppression activity of hepatic stellate cells in vivo

Author keywords

Bear bile; Chronic liver disease; Hepatic stellate cells; Immune; Inhibition

Indexed keywords

BEAR BILE; CHINESE DRUG; CYTOKINE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

EID: 84865180829     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: 10.5754/hge10637     Document Type: Article
Times cited : (2)

References (31)
  • 2
    • 58149380828 scopus 로고    scopus 로고
    • Comprehensive analysis of the alpha-fetoprotein-specific CD8+ T-cell responses in patients with hepatocellular carcinoma
    • Thimme R, Neagu M, Boettler T, et al.: Comprehensive analysis of the alpha-fetoprotein-specific CD8+ T-cell responses in patients with hepatocellular carcinoma. Hepatology 2008; 48:1821-1833.
    • (2008) Hepatology , vol.48 , pp. 1821-1833
    • Thimme, R.1    Neagu, M.2    Boettler, T.3
  • 3
    • 79960763606 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy for hepatocellular carcinoma
    • Nakamoto Y, Kaneko S: Dendritic cell-based immunotherapy for hepatocellular carcinoma. Can To Kagaku Ryoho 2010; 37:413-416.
    • (2010) Can to Kagaku Ryoho , vol.37 , pp. 413-416
    • Nakamoto, Y.1    Kaneko, S.2
  • 4
    • 0036378352 scopus 로고    scopus 로고
    • Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells
    • Ladhams A, Schmidt C, Sing G, et al.: Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells. J Gastroenterol Hepatol 2002; 17:889-896.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 889-896
    • Ladhams, A.1    Schmidt, C.2    Sing, G.3
  • 5
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial
    • Takayama T, Sekine T, Makuuchi M, et al.: Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet 2000; 356:802-807.
    • (2000) Lancet , vol.356 , pp. 802-807
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3
  • 6
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W: Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 2005; 5:263-274.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 7
    • 0034031683 scopus 로고    scopus 로고
    • Local control of the immune response in the liver
    • Knolle PA, Gerken G: Local control of the immune response in the liver. Immunol Rev 2000; 174:21-34.
    • (2000) Immunol Rev , vol.174 , pp. 21-34
    • Knolle, P.A.1    Gerken, G.2
  • 8
    • 10644293881 scopus 로고    scopus 로고
    • Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice
    • Yu MC, Chen CH, Liang X, et al.: Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice. Hepatology 2004; 40:1312-1321.
    • (2004) Hepatology , vol.40 , pp. 1312-1321
    • Yu, M.C.1    Chen, C.H.2    Liang, X.3
  • 9
    • 59349089518 scopus 로고    scopus 로고
    • Bear bile: Dilemma of traditional medicinal use and animal protection
    • Feng Y, Siu K, Wang N, et al.: Bear bile: dilemma of traditional medicinal use and animal protection. J Ethnobiol Ethnomed 2009; 5:2.
    • (2009) J Ethnobiol Ethnomed , vol.5 , pp. 2
    • Feng, Y.1    Siu, K.2    Wang, N.3
  • 10
    • 30744461583 scopus 로고    scopus 로고
    • Inhibitory effects of bear bile powder on dimethylnitrosamine-induced liver fibrosis in rats
    • In Chinese with English abstract
    • Quan MJ, Jin RS, Piao L, Piao DM: Inhibitory effects of bear bile powder on dimethylnitrosamine-induced liver fibrosis in rats. World Chin J Digestol 2005; 13:2487-2490 (In Chinese with English abstract).
    • (2005) World Chin J Digestol , vol.13 , pp. 2487-2490
    • Quan, M.J.1    Jin, R.S.2    Piao, L.3    Piao, D.M.4
  • 11
    • 4644349674 scopus 로고    scopus 로고
    • Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease
    • Steiling H, Muhlbauer M, Bataille F, et al.: Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease. Am J Pathol 2004; 165:1233-1241.
    • (2004) Am J Pathol , vol.165 , pp. 1233-1241
    • Steiling, H.1    Muhlbauer, M.2    Bataille, F.3
  • 12
    • 77953006325 scopus 로고    scopus 로고
    • A critical role of TRAIL expressed on cotransplanted hepatic stellate cells in prevention of islet allograft rejection
    • Yang HR, Hsieh CC, Wang L, et al.: A critical role of TRAIL expressed on cotransplanted hepatic stellate cells in prevention of islet allograft rejection. Microsurgery 2010; 30(4):332-337.
    • (2010) Microsurgery , vol.30 , Issue.4 , pp. 332-337
    • Yang, H.R.1    Hsieh, C.C.2    Wang, L.3
  • 13
    • 39549101769 scopus 로고    scopus 로고
    • Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies
    • Ohta S, Ueda Y, Yaguchi M, et al.: Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies. Immunology 2008; 123:566-574.
    • (2008) Immunology , vol.123 , pp. 566-574
    • Ohta, S.1    Ueda, Y.2    Yaguchi, M.3
  • 14
    • 0022635431 scopus 로고
    • Periductal fibrosis and lipocytes fat-storing cells or Ito cells during biliary atresia in the lamprey
    • Yamamoto K, Sargent PA, Fisher MM, Youson JH: Periductal fibrosis and lipocytes fat-storing cells or Ito cells during biliary atresia in the lamprey. Hepatology 1986; 6:54-59.
    • (1986) Hepatology , vol.6 , pp. 54-59
    • Yamamoto, K.1    Sargent, P.A.2    Fisher, M.M.3    Youson, J.H.4
  • 16
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W: Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006; 6:295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 17
    • 12044260143 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL: Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993; 328:1828-1835.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 18
    • 0029665279 scopus 로고    scopus 로고
    • Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells
    • Hellerbrand, Wang SC, Tsukamoto H, Brenner DA, Rippe RA: Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Hepatology 1996; 24:670-676.
    • (1996) Hepatology , vol.24 , pp. 670-676
    • Hellerbrand1    Wang, S.C.2    Tsukamoto, H.3    Brenner, D.A.4    Rippe, R.A.5
  • 19
    • 34250174821 scopus 로고    scopus 로고
    • ICAM-1 expressed on hepatic stellate cells plays an important role in immune regulation
    • Yin Z, Jiang G, Fung JJ, Lu L, Qian S: ICAM-1 expressed on hepatic stellate cells plays an important role in immune regulation. Microsurgery 2007; 27:328-332.
    • (2007) Microsurgery , vol.27 , pp. 328-332
    • Yin, Z.1    Jiang, G.2    Fung, J.J.3    Lu, L.4    Qian, S.5
  • 20
    • 33745402810 scopus 로고    scopus 로고
    • Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86
    • Manzotti CN, Liu MK, Burke F, Dussably L, Zheng Y, Sanson DM: Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86. Eur J Immunol 2006; 36:1413-1422.
    • (2006) Eur J Immunol , vol.36 , pp. 1413-1422
    • Manzotti, C.N.1    Liu, M.K.2    Burke, F.3    Dussably, L.4    Zheng, Y.5    Sanson, D.M.6
  • 21
    • 34547794178 scopus 로고    scopus 로고
    • PD-1 and PD-1 ligands: From discovery to clinical application
    • Okazaki T, Honjo T: PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol 2007; 19:813-824.
    • (2007) Int Immunol , vol.19 , pp. 813-824
    • Okazaki, T.1    Honjo, T.2
  • 23
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H, Strome SE, Salomao DR, et al.: Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8:793-800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 24
    • 67449094451 scopus 로고    scopus 로고
    • Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma
    • Amann T, Bataille F, Spruss T, et al.: Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma. Cancer Sci 2009; 100:646-653.
    • (2009) Cancer Sci , vol.100 , pp. 646-653
    • Amann, T.1    Bataille, F.2    Spruss, T.3
  • 25
    • 0034955574 scopus 로고    scopus 로고
    • Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas
    • Theret N, Musso O, Turlin B, et al.: Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas. Hepatology 2001; 34:82-88.
    • (2001) Hepatology , vol.34 , pp. 82-88
    • Theret, N.1    Musso, O.2    Turlin, B.3
  • 26
    • 0030587071 scopus 로고    scopus 로고
    • I-309/T-cell activation gene-3 chemokine protects murine T-cell lymphomas against dexamethasone-induced apoptosis
    • Van Snick J, Houssiau F, Proost P, Van Damme J, Renauld JC: I-309/T-cell activation gene-3 chemokine protects murine T-cell lymphomas against dexamethasone-induced apoptosis. J Immunol 1996; 157:2570-2576.
    • (1996) J Immunol , vol.157 , pp. 2570-2576
    • Van Snick, J.1    Houssiau, F.2    Proost, P.3    Van Damme, J.4    Renauld, J.C.5
  • 27
    • 0030717692 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
    • Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP: Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 1997; 74:111-122.
    • (1997) Eur J Cell Biol , vol.74 , pp. 111-122
    • Gomez, D.E.1    Alonso, D.F.2    Yoshiji, H.3    Thorgeirsson, U.P.4
  • 28
    • 0028886516 scopus 로고
    • Over-expression of tissue inhibitor of matrix metalloproteinases TIMP1 and T1MP2 suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma
    • Kawamata H, Kawai K, Kameyama S, et al.: Over-expression of tissue inhibitor of matrix metalloproteinases TIMP1 and T1MP2 suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma. Int J Cancer 1995; 63:680-687.
    • (1995) Int J Cancer , vol.63 , pp. 680-687
    • Kawamata, H.1    Kawai, K.2    Kameyama, S.3
  • 29
    • 57149107119 scopus 로고    scopus 로고
    • The effects of IL-6 on CD4 T-cell responses
    • Dienz O, Rincon M: The effects of IL-6 on CD4 T-cell responses. Clin Immunol 2009; 130:27-33.
    • (2009) Clin Immunol , vol.130 , pp. 27-33
    • Dienz, O.1    Rincon, M.2
  • 30
    • 68549136586 scopus 로고    scopus 로고
    • Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients
    • Zhou J, Ding T, Pan W, Zhu LY, Li L, Zheng L: Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients. Int J Cancer 2009; 125:1640-1648.
    • (2009) Int J Cancer , vol.125 , pp. 1640-1648
    • Zhou, J.1    Ding, T.2    Pan, W.3    Zhu, L.Y.4    Li, L.5    Zheng, L.6
  • 31
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • Ghirtnghelli F, Menard C, Puig PE, et al.: Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 2007; 56:641-648.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 641-648
    • Ghirtnghelli, F.1    Menard, C.2    Puig, P.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.