Cytotoxic fraction from Artemisia sacrorum Ledeb. against three human cancer cell lines and separation and identification of its compounds

Natural Product Research

Volumn 26, Issue 16, 2012, Pages 1483-1491

  Piao, Guang Chun ^a   Li, Yi Xian ^a   Yuan, Hai Dan ^a,b   Jin, Guang Zhu ^a  

^a YANBIAN UNIVERSITY   (China)

^b Kyung Hee University   (South Korea)

Author keywords

acacetin; anti cancer cytotoxicity; Artemisia sacrorum Ledeb.; genkwanin; isoscopoletin; scopoletin

Indexed keywords

ACACETIN; ALCOHOL; ARTEMISIA SACRORUM EXTRACT; DICHLOROMETHANE; GENKWANIN; ISOSCOPOLETIN; PLANT EXTRACT; RESIN; SCOPOLETIN; SOLVENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTEMISIA; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEK293; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; ARTEMISIA; FLAVONES; HEP G2 CELLS; HT29 CELLS; HUMANS; MCF-7 CELLS; SCOPOLETIN;

EID: 84865164389     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2011.565473     Document Type: Article

References (30)

1. Bang, M.H., Han, M.W., Song, M.C., Cho, J.G., Chung, H.G., Jeong, T.S., , Baek, N.I. (2008). A cytotoxic and apoptosis-inducing sesquiterpenoid isolated from the aerial parts of Artemisia princeps PAMPANINI (Sajabalssuk). Chemical and Pharmaceutical Bulletin, 56, 1168-1172.
2. Cui, S.N., Song, J.F., Piao, J.Z., Wen, M.L., Piao, M.J., Piao, L.X., , Lu, D.Z. (Eds) (1995). Medicine of Korean nationality in China. China: Yanbian People's Publishing House, pp. 8-9.
3. Ding, L., Liu, G.A., He, L., & Wang, H.Q. (2005). Studies on the flavonoid constituents in herb of Eremosparton songoricum. China Journal of Chinese Materia Medica, 30, 126-128. (Pubitemid 44366797)
4. Duan, C.H., Shi, B.J., Wu, L.H., Chou, G.X., & Wang, Z.T. (2007). Studies on chemical constituents of Gentiana waltoniiBurkill. China Journal of Natural Medicine, 6, 417-419.
5. Fan, L.Y., Zhang, S.H., Li, J.M., Sun, W., & Ren, J. (2007). Research advances on chemical constituents and pharmacological activities of Artemisia sacrorum Ledeb. Lishizhen Medicine and Materia Medica Research, 18, 1779-1780.
6. Firestone, G.L., & Sundar, S.N. (2009). Anticancer activities of artemisinin and its bioactive derivatives. Expert Review in Molecular Medicine, 11, e32.
7. Hsua, Y.L., Kuob, P.L., Liuc, C.F., & Lina, C.C. (2004). Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells. Cancer Letters, 212, 53-60.
8. Jeong, M.A., Lee, K.W., Yoon, D.Y., & Lee, H.J. (2007). Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and-2 in cultured human mammary epithelial cells. Annals of the New York Academy of Sciences, 1095, 458-466.
9. Jilin Bureau of Public Health, Changchun, China (Eds) (1977). Jilin province drug standards, 251.
10. Jones, W.P., Lobo-Echeverri, T., Mi, Q., Chai, H.B., Soejarto, D.D., Cordell, G.A., , Kinghorn, A.D. (2007). Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida. Journal of Natural Products, 70, 372-377. (Pubitemid 46595742)
11. Kim, Y.S., Bahn, K.N., Hah, C.K., Gang, H.I., & Ha, Y.L. (2008). Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaris. Journal of Food Science, 73, T16-20.
12. Kometani, T., Yoshino, I., Miura, N., Okazaki, H., Ohba, T, Takenaka, T., , Maehara, Y. (2009). Benzo[a]pyrene promotes proliferation of human lung cancer cells by accelerating the epidermal growth factor receptor signaling pathway. Cancer Letters, 278, 27-33.
13. Li, Z.P., Gao, S., Hao, C.S., & Fan, G.M. (2000). Studies on chemical constituents from the flower of Albizzia julibrissin Durazz (article in Chinese). China Journal of Chinese Materia Medica, 25, 103-104.
14. Li, B., Zhang, D.M., & Luo, Y.M. (2006). Chemical constituents from roots of Ficus hirta. China Journal of Chinese Materia Medica, 31, 113-115.
15. Liu, X.L., Sun, J.Y., Li, H.Y., Zhang, L., & Qian, B.C. (2000). Extraction and isolation of active component for inhibiting PC3 cell proliferation in vitro from the fruit of Lycium barbarum L. China Journal of Chinese Materia Medica, 25, 481-483.
16. Luo, Y.J., Xiao, X.F., & Wang, Z.L. (2009). Studies on chemical constituents of Stenoloma chusana (L)Ching. China Journal of Chemical Research and Application, 21, 97-99.
17. Manuele, M.G., Ferraro, G., Barreiro Arcos, M.L., Ló pez, P., Cremaschi, G., & Anesini, C. (2006). Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes. Life Sciences, 79, 2043-2048. (Pubitemid 44528585)
18. McGovern, P.E., Christofidou-Solomidou, M., Wang, W., Dukes, F., Davidson, T., & El-Deiry, W.S. (2010). Anticancer activity of botanical compounds in ancient fermented beverages (review). International Journal of Oncology, 37, 5-14.
19. Pan, M.H., Lai, C.S., Hsu, P.C., & Wang, Y.J. (2005). Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species. Journal of Agricultural and Food Chemistry, 53, 620-630.
20. Pan, M.H., Lai, C.S., Wang, Y.J., & Ho, C.T. (2006). Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochemical Pharmacology, 72, 1293-1303.
21. Piao, G.C., & Quan, Y.C. (2007). Protective effects of extracts of Artemisia sacrorum Ledeb. on acute hepatic injury in mice. Lishizhen Medicine and Materia Medica Research, 18, 1646-1647.
22. Shen, K.H., Hung, S.H., Yin, L.T., Huang, C.S., Chao, C.H., Liu, C.L., & Shih, Y.W. (2010). Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway. Molecular and Cellular Biochemistry, 333, 279-291.
23. Stavri, M., Ford, C.H., Bucar, F., Streit, B., Hall, M.L., Williamson, R.T., , Gibbons, S. (2005). Bioactive constituents of Artemisia monosperma. Phytochemistry, 66, 233-239. (Pubitemid 40126424)
24. Tan, R.X., Zheng, W.F., & Tang, H.Q. (1998). Biologically active substances from the genus Artemisia. Planta Medica, 64, 295-302. (Pubitemid 28234263)
25. Wen, J., Shi, H., Xu, Z., Chang, H., Jia, C., Zan, K., , Tu, P. (2010). Dimeric guaianolides and sesquiterpenoids from Artemisia anomala. Journal of Natural Products, 73, 67-70.
26. Yan, Z.K., & Li, W.L. (Eds) (1997). Color atlas of medicinal plants in Changbaishan mountain in China. Beijing, China: People's Health Publishing House, p. 415.
27. Yuan, H.D., Jin, G.Z., & Piao, G.C. (2009). Protective effects of the active part of Artemisia sacrorum Ledeb. against acetaminophen-induced liver injury in mice. Biological and Pharmaceutical Bulletin, 32, 1683-1688.
28. Yuan, H.D., Jin, G.Z., & Piao, G.C. (2010). Hepatoprotective effects of an active part from Artemisia sacrorum Ledeb. against acetaminophen-induced toxicity in mice. Journal of Ethnopharmacology, 127, 528-533.
29. Zhang, D.Z. (2006). Studies on new susquiterpenes in Artemisia sacrorum Ledeb. Guangdong Trace Elements Science, 13, 59-63.
30. Zhang, W., Zhang, W.D., Li, T.Z., Zhang, C., Liu, R.H., Zhou, Y., & Su, J. (2005). Studies on the chemical constituents in roots of Daphne odora var. atrocaulis. China Journal of Chinese Materia Medica, 30, 513-515. (Pubitemid 44724679)