Tiron protects against UVB-induced senescence-like characteristics in human dermal fibroblasts by the inhibition of superoxide anion production and glutathione depletion

Australasian Journal of Dermatology

Volumn 53, Issue 3, 2012, Pages 172-180

  Fang, Yong ^a   Hu, Xiao Hui ^a   Jia, Zhi Gang ^a   Xu, Mang Hua ^a   Guo, Zhu Ying ^a   Gao, Feng Hou ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

fibroblast; reactive oxygen species; senescence; Tiron; ultraviolet irradiation

Indexed keywords

BETA GALACTOSIDASE; GLUTATHIONE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; PROTEIN P16; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; SOMATOMEDIN C; SUPEROXIDE; SUPEROXIDE DISMUTASE; TIRON;

ARTICLE; CELL AGING; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; DOWN REGULATION; ENZYME ACTIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; PHOTOAGING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; ULTRAVIOLET B RADIATION; WESTERN BLOTTING;

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT; ANTIOXIDANTS; APOPTOSIS; CELL AGING; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FIBROBLASTS; GLUTATHIONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-MYC; RETINOBLASTOMA PROTEIN; SUPEROXIDE DISMUTASE; SUPEROXIDES; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 84865142044     PISSN: 00048380     EISSN: 14400960     Source Type: Journal    
DOI: 10.1111/j.1440-0960.2012.00912.x     Document Type: Article

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