Important role of Maillard reaction in the protective effect of heat-processed ginsenoside Re-serine mixture against cisplatin-induced nephrotoxicity in LLC-PK1 cells

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5475-5479

  Lee, Ji Hwan ^a   Lee, Woojung ^a   Lee, Seungyong ^a   Jung, Yujung ^a   Park, Soon Hye ^a   Choi, Pilju ^a   Kim, Su Nam ^a   Ham, Jungyeob ^a   Kang, Ki Sung ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

Ginsenoside Re; Heat processing; Maillard reaction; Nephrotoxicity; Oxidative stress

Indexed keywords

ANTIOXIDANT; CARBON; CISPLATIN; GINSENOSIDE RE; GINSENOSIDE RG 2; GINSENOSIDE RG 6; GLUCOSE; SAPONIN; SERINE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; DRUG INDUCED DISEASE; DRUG STRUCTURE; GLYCATION; HEATING; NEPHROTOXICITY; OXIDATIVE STRESS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; CISPLATIN; CYTOPROTECTION; CYTOTOXINS; GINSENOSIDES; HOT TEMPERATURE; KIDNEY; LLC-PK1 CELLS; MAILLARD REACTION; OXIDATIVE STRESS; PANAX; SERINE; SWINE;

EID: 84865140553     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.018     Document Type: Article

References (17)

1. X.M. Chen, and D.D. Kitts Mol. Cell Biochem. 364 2012 147
2. Y.J. Lee, H.Y. Kim, K.S. Kang, J.G. Lee, T. Yokozawa, and J.H. Park Bioorg. Med. Chem. Lett. 18 2008 4515
3. Y. Cai, Q. Luo, M. Sun, and H. Corke Life Sci. 74 2004 2157
4. F.J. Morales, and S. Jiménez-Pérez Food Chem. 72 2001 119
5. K. Yanagimoto, H. Ochi, K.G. Lee, and T. Shibamoto J. Agric. Food Chem. 52 2004 592
6. K.S. Kang, H.Y. Kim, J.S. Pyo, and T. Yokozawa Biol. Pharm. Bull. 29 2006 750
7. T.S. Samaras, P.A. Camburn, S.X. Chandra, M.H. Gordon, and J.M. Ames J. Agric. Food Chem. 53 2005 8068
8. T. Hatano, R. Edamatsu, M. Hiramatsu, A. Mori, Y. Fujita, T. Yasuhara, T. Yoshida, and T. Okuda Chem. Pharm. Bull. 2016 1989 37
9. Q.Y. Zhu, R.M. Hackman, J.L. Ensunsa, R.R. Holt, and C.L. Keen J. Agric. Food Chem. 50 2002 6929
10. T. Yokozawa, E.J. Cho, Y. Hara, and K. Kitani J. Agric. Food Chem. 48 2000 5068
11. J.T. Hartmann, L.M. Fels, S. Knop, H. Stolt, L. Kanz, and C. Bokemeyer Invest. New Drugs 18 2000 281
12. R.P. Miller, R.K. Tadagavadi, G. Ramesh, and W.B. Reeves Toxins 2 2010 2490
13. D. Wang, and S. Lippard J. Nat. Rev. Drug Discov. 4 2005 307
14. K.J. Kelly, S.M. Meehan, R.B. Colvin, W.W. Williams, and J.V. Bonventre Kidney Int. 56 1999 922
15. J. Deng, Y. Kohda, H. Chiao, Y. Wang, X. Hu, S. Hewitt, T. Miyaja, P. McLeroy, B. Nibhanupudy, S. Li, and R. Star Kidney Int. 60 2001 2118
16. G. Ramesh, and W.B. Reeves Kidney Int. 65 2004 490
17. G. Ramesh, and W.B. Reeves Am. J. Physiol. Renal Physiol. 289 2005 F166