Argan oil nanoemulsions as new hydrophobic drug-loaded delivery system for transdermal application

Journal of Biomedical Nanotechnology

Volumn 8, Issue 5, 2012, Pages 843-848

  Lococo, D ^a,b   Mora Huertas, C E ^a,b   Fessi, H ^a,b   Zaanoun, I ^c   Elaissari, A ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

^c Universiapolis   (Morocco)

Author keywords

Argan oil; Diclofenac; Encapsulation; Nanoemulsion; Niosome; Sorbitan ester; Transdermal

Indexed keywords

ARGAN OIL; DICLOFENAC; NANOEMULSION; NIOSOME; TRANSDERMAL;

DISPERSIONS; ESTERIFICATION; ESTERS; HYDROPHOBICITY; ZETA POTENTIAL;

ENCAPSULATION;

ARGAN OIL; DICLOFENAC; DRUG CARRIER; NIOSOME; UNCLASSIFIED DRUG;

ARTICLE; DISPERSION; DRUG FORMULATION; DRUG STABILITY; ENCAPSULATION; NANOEMULSION; PARTICLE SIZE; PHYSICAL CHEMISTRY; ZETA POTENTIAL;

ADMINISTRATION, CUTANEOUS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DELAYED-ACTION PREPARATIONS; DICLOFENAC; DIFFUSION; EMULSIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NANOCAPSULES; PLANT OILS;

EID: 84865140373     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1445     Document Type: Article

References (21)

1. B. W. Barry, Novel mechanisms and devices to enable successful transdermal drug delivery. Eur. J. Pharm. Sci. 14, 101 (2001).
2. P. L. Honeywell-Nguyen and J. A. Bouwstra, Vesicles as a tool for transdermal and dermal delivery. Drug Discov. Today 2, 67 (2005).
3. M. Foldvari, Non-invasive administration of drugs through the skin: Challenges in delivery system design. PSTT 3, 417 (2000).
4. A. Naik, Y. N. Kalia, and R. H. Guy, Transdermal drug delivery: Overcoming the skin's barrier function. PSTT 3, 318 (2000).
5. I. F. Uchegbu and S. P. Vyas, Non-ionic surfactant based vesicles (niosomes) in drug delivery. Int. J. Pharm. 172, 33 (1998).
6. D. Paolino, D. Cosco, R. Muzzalupo, E. Trapasso, N. Picci, and M. Fresta, Innovative bola-surfactant niosomes as topical delivery systems of 5-fluorouracil for the treatment of skin cancer. Int. J. Pharm. 353, 233 (2008).
7. G. Cevc and U. Vierl, Nanotechnology and the transdermal route A state of the art review and critical appraisal. J. Control. Rel. 141, 277 (2010).
8. F. Shakeel and W. Ramadan, Transdermal delivery of anticancer drug caffeine from water-in-oil nanoemulsions. Colloid Surface B 75, 356 (2010).
9. M. Kong, X. G. Chen, D. K. Kweon, and H. J. Park, Investigations on skin permeation of hyaluronic acid based nanoemulsion as transdermal carrier. Carbohyd. Polym. 86, 837 (2011).
10. K. S. Chandraprakash, N. Udupa, P. Umadevi, and G. K. Pillai, Pharmacokinetic evaluation of surfactant vesicle-entrapped methotrexate in tumor-bearing mice. Int. J. Pharm. 61, R1 (1990).
11. G. N. Devaraj, S. R. Parakh, R. Devraj, S. S. Apte, B. R. Rao, and D. Rambhau, Release studies on niosomes containing fatty alcohols as bilayer stabilizers instead of cholesterol. J. Colloid Interface Sci. 251, 360 (2002).
12. J. D. Yadav, P. R. Kulkarni, K. A. Vaidya, and G. T. Shelke, Niosomes: A review. J. Pharm. Res. 4, 632 (2011).
13. T. Tadros, P. Izquierdo, J. Esquena, and C. Solans, Formation and stability of nano-emulsions. Adv. Colloid Interface Sci. 108-109, 303 (2004).
14. B. Matthäus, D. Guillaume, S. Gharby, A. Haddad, H. Harhar, and Z. Charrouf, Effect of processing on the quality of edible argan oil. Food Chem. 120, 426 (2010).
15. M. Cherki, H. Berrougui, A. Drissi, A. Adlouni, and A. Khalil, Argan oil: Which benefits on cardiovascular diseases? Pharmacol. Res. 54, 1 (2006).
16. T. Yoshioka, B. Sternberg, and A. T. Florence, Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60 and 80) and a sorbitan triester (Span 85). Int. J. Pharm. 105, 1 (1994).
17. R. C. Rowe, P. J. Sheskey, and S. C. Owen (eds.), Handbook of Pharmaceutical Excipients, Pharmaceutical Press, Great Britain (2006).
18. G. Cevc, Lipid vesicles and other colloids as drug carriers on the skin. Adv. Drug Deliver. Rev. 56, 675 (2004).
19. C. E. Mora, O. Garrigues, H. Fessi, and A. Elaissari, Nanocapsules prepared via nanoprecipitation and emulsification-diffusion methods: Comparative study. Eur. J. Pharm. Biopharm. 80, 235 (2012).
20. M. El-Mahrab, V. Rosilio, M. A. Bolzinger, P. Chaminade, and J. L. Grossiord, Assessment of oil polarity: Comparison of evaluation methods. Int. J. Pharm. 348, 89 (2008).
21. A. Llinàs, J. C. Burley, K. J. Box, R. C. Glen, and J. M. Goodman, Diclofenac solubility: Independent determination of the intrinsic solubility of three crystal forms. J. Med. Chem. 50, 979 (2007).