High levels of glucose induce "metabolic memory" in cardiomyocyte via epigenetic histone H3 lysine 9 methylation

Molecular Biology Reports

Volumn 39, Issue 9, 2012, Pages 8891-8898

  Yu, Xi Yong ^a   Geng, Yong Jian ^b   Liang, Jia Liang ^a   Zhang, Saidan ^c   Lei, He Ping ^a   Zhong, Shi Long ^a   Lin, Qiu Xiong ^a   Shan, Zhi Xin ^a   Lin, Shu Guang ^a   Li, Yangxin ^b  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b UNIVERSITY OF TEXAS   (United States)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; Chromatin remodeling; Epigenetic regulation; Inflammation; Metabolic memory

Indexed keywords

CYTOCHROME C; GLUCOSE; HISTONE H3; INTERLEUKIN 6; LYSINE; MANNITOL; MESSENGER RNA; METHYLTRANSFERASE; METHYLTRANSFERASE SUV39H1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LEVEL; CHROMATIN IMMUNOPRECIPITATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPIGENETICS; HEART MUSCLE CELL; HISTONE METHYLATION; IMMUNOBLOTTING; INFLAMMATION; LYSINE METHYLATION; METABOLIC MEMORY; METABOLIC PARAMETERS; METHYLATION; NONHUMAN; OSMOLARITY; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION;

CELL LINE; CELLS, CULTURED; CYTOKINES; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; GLUCOSE; HISTONES; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LYSINE; METHYLATION; MYOCYTES, CARDIAC; PROMOTER REGIONS, GENETIC;

EID: 84865130642     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1756-z     Document Type: Article

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