Stem cell gene Girdin: A potential early liver metastasis predictor of colorectal cancer

Molecular Biology Reports

Volumn 39, Issue 9, 2012, Pages 8717-8722

  Liu, Chen ^a   Xue, Hongpeng ^b   Lu, Yixia ^b   Chi, Baorong ^a  

^a JILIN UNIVERSITY   (China)

^b HEILONGJIANG PROVINCIAL HOSPITAL   (China)

Author keywords

Colorectal cancer; Girdin protein; Metastasis; Survival

Indexed keywords

ONCOPROTEIN; PROTEIN GIRDIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER INVASION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; DISTANT METASTASIS; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GIRDIN GENE; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE; PREDICTION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SURVIVAL RATE; TUMOR CELL;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MICROFILAMENT PROTEINS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; STEM CELLS; TUMOR MARKERS, BIOLOGICAL; VESICULAR TRANSPORT PROTEINS;

EID: 84865130610     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1731-8     Document Type: Article

References (16)

1. Center MM, Jemal A, Smith RA, Ward E (2009) Worldwide variations in colorectal cancer. CA Cancer J Clin 59:366-378
2. Merrill RM, Anderson AE (2011) Risk-adjusted colon and rectal cancer incidence rates in the United States. Dis Colon Rectum 54(10):1301-1306
3. Drury LJ, Ziarek JJ, Gravel S, Veldkamp CT, Takekoshi T, Hwang ST, Heveker N, Volkman BF, Dwinell MB (2011) Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proc Natl Acad Sci USA 108(43):17655-17660
4. Serra V, Scaltriti M, Prudkin L, Eichhorn PJ, Ibrahim YH, Chandarlapaty S, Markman B, Rodriguez O, Guzman M, Rodriguez S, Gili M, Russillo M, Parra JL, Singh S, Arribas J, Rosen N, Baselga J (2011) PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer. Oncogene 30(22):2547-2557
5. Heckmann D, Laufs S, Maier P, Zucknick M, Giordano FA, Veldwijk MR, Eckstein V, Wenz F, Zeller WJ, Fruehauf S, Allgayer HA (2011) Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion. Onkologie 34(10):502-508
6. Jiang P, Enomoto A, Jijiwa M, Kato T, Hasegawa T, Ishida M, Sato T, Asai N, Murakumo Y, Takahashi M (2008) An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer Res 68(5):1310-1318 (Pubitemid 351346837)
7. Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P (2011) Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer. FASEB J 25(2):590-599
8. Ling Y, Jiang P, Cui SP, Ren YL, Zhu SN, Yang JP, Du J, Zhang Y, Liu JY, Zhang B (2011) Clinical implications for girdin protein expression in breast cancer. Cancer Invest 29(6):405-410
9. Liu C, Zhang Y, Xu H, Zhang R, Li H, Lu P, Jin F (2011) Girdin protein: a new potential distant metastasis predictor of breast cancer. Med Oncol. doi: 10.1007/s12032-011-0087-6
10. Konishi K, Watanabe Y, Shen L, Guo Y, Castoro RJ, Kondo K, Chung W, Ahmed S, Jelinek J, Boumber YA, Estecio MR, Maegawa S, Kondo Y, Itoh F, Imawari M, Hamilton SR, Issa JP (2011) DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One 6(11):e27889
11. Boonsirikamchai P, Asran MA, Maru DM, Vauthey JN, Kaur H, Kopetz S, Loyer EM (2011) CT findings of response and recurrence, independent of change in tumor size, in colorectal liver metastasis treated with bevacizumab. AJR Am J Roentgenol 197(6):W1060-W1066
12. Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, Huo L, Cheng X, Chen YJ, Li CW, Jeng LB, Hsu JL, Li LY, Tan A, Curley SA, Ellis LM, Dubois RN (2011) Hung MC.APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. J Clin Invest 121(11):4526-4536
13. Enomoto A, Ping J, Takahashi M (2006) Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways. Ann N Y Acad Sci 1086:169-184 (Pubitemid 47084384)
14. Weng L, Enomoto A, Ishida-Takagishi M, Asai N, Takahashi M (2010) Girding for migratory cues: roles of the Akt substrate Girdin in cancer progression and angiogenesis. Cancer Sci 101(4):836-842
15. Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, Ohka F, Motomura K, Kondo Y, Miyata T, Takahashi M, Wakabayashi T (2012) Girdin maintains the stemness of glioblastoma stem cells. Oncogene 31:2715-2724
16. Ghosh P, Garcia-Marcos M, Farquhar MG (2011) GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression. Cell Adhes Migr 5(3):237-248