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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5392-5395

2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors

(16) Hua, Zihao a Huang, Xin a Bregman, Howard a Chakka, Nagasree a Dimauro, Erin F a Doherty, Elizabeth M a Goldstein, Jon a Gunaydin, Hakan a Huang, Hongbing a Mercede, Stephanie a Newcomb, John a Patel, Vinod F a Turci, Susan M a Yan, Jie a Wilson, Cindy a Martin, Matthew W a

a AMGEN INC (United States)

Author keywords

Catenin; Casein kinase 1; GSK3 ; Wnt pathway

Indexed keywords

2 PHENYLAMINO 6 CYANO 1H BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; CASEIN KINASE IGAMMA INHIBITOR; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CRYSTAL STRUCTURE; DRUG BINDING; DRUG CLEARANCE; DRUG HALF LIFE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; HYDROPHOBICITY; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY;

ANIMALS; BENZIMIDAZOLES; BETA CATENIN; BINDING SITES; CASEIN KINASE I; HUMANS; MICE; MODELS, MOLECULAR; PROTEIN ISOFORMS; PROTEIN KINASE INHIBITORS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865125787 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.07.046 Document Type: Article

Times cited : (22)

References (20)

1
- 13844294211
- U. Knippschild, A. Gocht, S. Wolff, N. Huber, J. Lohler, and M. Stoter Cell. Signalling 17 2005 675
- (2005) Cell. Signalling , vol.17 , pp. 675
- Knippschild, U.¹ Gocht, A.² Wolff, S.³ Huber, N.⁴ Lohler, J.⁵ Stoter, M.⁶

2
- 0037155691
- C. Liu, Y. Li, M. Semenov, C. Han, G.H. Baeg, Y. Tan, Z. Zhang, X. Lin, and X. He Cell 108 2002 837
- (2002) Cell , vol.108 , pp. 837
- Liu, C.¹ Li, Y.² Semenov, M.³ Han, C.⁴ Baeg, G.H.⁵ Tan, Y.⁶ Zhang, Z.⁷ Lin, X.⁸ He, X.⁹

3
- 0033598401
- J.M. Peters, R.M. McKay, J.P. McKay, and J.M. Graff Nature 401 1999 345
- (1999) Nature , vol.401 , pp. 345
- Peters, J.M.¹ McKay, R.M.² McKay, J.P.³ Graff, J.M.⁴

4
- 0033607057
- C. Sakanaka, P. Leong, L. Xu, S.D. Harrison, and L.T. Williams Proc. Natl. Acad. Sci. U.S.A. 96 1999 12548
- (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 12548
- Sakanaka, C.¹ Leong, P.² Xu, L.³ Harrison, S.D.⁴ Williams, L.T.⁵

5
- 1842424730
- W. Swiatek, I.C. Tsai, L. Klimowski, A. Pepler, J. Barnette, H.J. Yost, and D.M. Virshup J. Biol. Chem. 279 2004 13011
- (2004) J. Biol. Chem. , vol.279 , pp. 13011
- Swiatek, W.¹ Tsai, I.C.² Klimowski, L.³ Pepler, A.⁴ Barnette, J.⁵ Yost, H.J.⁶ Virshup, D.M.⁷

6
- 44149108488
- C. Brockschmidt, H. Hirner, N. Huber, T. Eismann, A. Hillenbrand, G. Giamas, B. Radunsky, O. Ammerpohl, B. Bohm, D. Henne-Bruns, H. Kalthoff, F. Leithauser, A. Trauzold, and U. Knippschild Gut. 57 2008 799
- (2008) Gut. , vol.57 , pp. 799
- Brockschmidt, C.¹ Hirner, H.² Huber, N.³ Eismann, T.⁴ Hillenbrand, A.⁵ Giamas, G.⁶ Radunsky, B.⁷ Ammerpohl, O.⁸ Bohm, B.⁹ Henne-Bruns, D.¹⁰ Kalthoff, H.¹¹ Leithauser, F.¹² Trauzold, A.¹³ Knippschild, U.¹⁴

7
- 77749258756
- S.Y. Kim, I.F. Dunn, R. Firestein, P. Gupta, L. Wardwell, K. Repich, A.C. Schinzel, B. Wittner, S.J. Silver, D.E. Root, J.S. Boehm, S. Ramaswamy, E.S. Lander, and W.C. Hahn PLoS One 5 2010 e8979
- (2010) PLoS One , vol.5 , pp. 8979
- Kim, S.Y.¹ Dunn, I.F.² Firestein, R.³ Gupta, P.⁴ Wardwell, L.⁵ Repich, K.⁶ Schinzel, A.C.⁷ Wittner, B.⁸ Silver, S.J.⁹ Root, D.E.¹⁰ Boehm, J.S.¹¹ Ramaswamy, S.¹² Lander, E.S.¹³ Hahn, W.C.¹⁴

8
- 28644444440
- G. Davidson, W. Wu, J. Shen, J. Bilic, U. Fenger, P. Stannek, A. Glinka, and C. Niehrs Nature 438 2005 867
- (2005) Nature , vol.438 , pp. 867
- Davidson, G.¹ Wu, W.² Shen, J.³ Bilic, J.⁴ Fenger, U.⁵ Stannek, P.⁶ Glinka, A.⁷ Niehrs, C.⁸

9
- 57649116365
- X. Guo, D.S. Waddell, W. Wang, Z. Wang, N.T. Liberati, S. Yong, X. Liu, and X.F. Wang Oncogene 27 2008 7235
- (2008) Oncogene , vol.27 , pp. 7235
- Guo, X.¹ Waddell, D.S.² Wang, W.³ Wang, Z.⁴ Liberati, N.T.⁵ Yong, S.⁶ Liu, X.⁷ Wang, X.F.⁸

10
- 77958171338
- C.A. Thorne, A.J. Hanson, J. Schneider, E. Tahinci, D. Orton, C.S. Cselenyi, K.K. Jernigan, K.C. Meyers, B.I. Hang, A.G. Waterson, K. Kim, B. Melancon, V.P. Ghidu, G.A. Sulikowski, B. LaFleur, A. Salic, L.A. Lee, D.M. Miller, and E. Lee Nat. Chem. Biol. 6 2010 829
- (2010) Nat. Chem. Biol. , vol.6 , pp. 829
- Thorne, C.A.¹ Hanson, A.J.² Schneider, J.³ Tahinci, E.⁴ Orton, D.⁵ Cselenyi, C.S.⁶ Jernigan, K.K.⁷ Meyers, K.C.⁸ Hang, B.I.⁹ Waterson, A.G.¹⁰ Kim, K.¹¹ Melancon, B.¹² Ghidu, V.P.¹³ Sulikowski, G.A.¹⁴ Lafleur, B.¹⁵ Salic, A.¹⁶ Lee, L.A.¹⁷ Miller, D.M.¹⁸ Lee, E.¹⁹

11
- 79957908556
- J.K. Cheong, T.H. Nguyen, H. Wang, P. Tan, P.M. Voorhoeve, S.H. Lee, and D.M. Virshup Oncogene 30 2011 2558
- (2011) Oncogene , vol.30 , pp. 2558
- Cheong, J.K.¹ Nguyen, T.H.² Wang, H.³ Tan, P.⁴ Voorhoeve, P.M.⁵ Lee, S.H.⁶ Virshup, D.M.⁷

12
- 84872672013
- Kinase binding assay, POC =% of control
- Kinase binding assay, POC =% of control.

13
- 65449133183
- F. Takahashi-Yanaga, and T. Sasaguri J. Pharm. Sci. 109 2009 179
- (2009) J. Pharm. Sci. , vol.109 , pp. 179
- Takahashi-Yanaga, F.¹ Sasaguri, T.²

14
- 1942453243
- A.L. Hopkins, C.R. Groom, and A. Alex Drug Discovery Today 9 2004 430
- (2004) Drug Discovery Today , vol.9 , pp. 430
- Hopkins, A.L.¹ Groom, C.R.² Alex, A.³

15
- 35748934487
- P.D. Lesson, and B. Springthorpe Nat. Rev. Drug Disc. 6 2007 881
- (2007) Nat. Rev. Drug Disc. , vol.6 , pp. 881
- Lesson, P.D.¹ Springthorpe, B.²

16
- 67649962669
- T. Ryckmans, M.P. Edwards, V.A. Horne, A.M. Correia, D.R. Owen, L.R. Thompson, I. Tran, M.F. Tutt, and T. Young Bioorg. Med. Chem. Lett. 19 2009 4406
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 4406
- Ryckmans, T.¹ Edwards, M.P.² Horne, V.A.³ Correia, A.M.⁴ Owen, D.R.⁵ Thompson, L.R.⁶ Tran, I.⁷ Tutt, M.F.⁸ Young, T.⁹

17
- 80052806086
- J.J. Cui, M. Tran-Dube, H. Shen, M. Nambu, P.-P. Kung, M. Pairish, L. Jia, J. Meng, L. Funk, I. Botrous, M. McTigue, N. Grodsky, K. Ryan, E. Padrique, G. Alton, S. Timofeevski, S. Yamazaki, Q. Li, H. Zou, J. Christensen, B. Mroczkowski, S. Bender, R.S. Kania, and M.P. Edwards J. Med. Chem. 54 2011 6342
- (2011) J. Med. Chem. , vol.54 , pp. 6342
- Cui, J.J.¹ Tran-Dube, M.² Shen, H.³ Nambu, M.⁴ Kung, P.-P.⁵ Pairish, M.⁶ Jia, L.⁷ Meng, J.⁸ Funk, L.⁹ Botrous, I.¹⁰ McTigue, M.¹¹ Grodsky, N.¹² Ryan, K.¹³ Padrique, E.¹⁴ Alton, G.¹⁵ Timofeevski, S.¹⁶ Yamazaki, S.¹⁷ Li, Q.¹⁸ Zou, H.¹⁹ Christensen, J.²⁰ more..

18
- 36148929378
- R.D. Carpenter, M. Andrei, E.Y. Lau, F.C. Lightstone, R. Liu, K.S. Lam, and M.J. Kurth J. Med. Chem. 50 2007 5863
- (2007) J. Med. Chem. , vol.50 , pp. 5863
- Carpenter, R.D.¹ Andrei, M.² Lau, E.Y.³ Lightstone, F.C.⁴ Liu, R.⁵ Lam, K.S.⁶ Kurth, M.J.⁷

19
- 33745136758
- V.I. Ognyanov, C. Balan, A.W. Bannon, Y. Bo, C. Dominguez, C. Fotsch, V.K. Gore, L. Klionsky, V.V. Ma, Y -X. Qian, R. Tamir, X. Wang, N. Xi, S. Xu, D. Zhu, N.R. Gavva, J.J.S. Treanor, and M.H. Norman J. Med. Chem. 49 2006 3719
- (2006) J. Med. Chem. , vol.49 , pp. 3719
- Ognyanov, V.I.¹ Balan, C.² Bannon, A.W.³ Bo, Y.⁴ Dominguez, C.⁵ Fotsch, C.⁶ Gore, V.K.⁷ Klionsky, L.⁸ Ma, V.V.⁹ Qian, Y.-X.¹⁰ Tamir, R.¹¹ Wang, X.¹² Xi, N.¹³ Xu, S.¹⁴ Zhu, D.¹⁵ Gavva, N.R.¹⁶ Treanor, J.J.S.¹⁷ Norman, M.H.¹⁸

20
- 84865108727
- PCT. Int. Appl. WO2010132598
- Bode, C.; Boezio, A.; Cheng, A. C.; Choquette, D.; Coats, J. R.; Copeland, K. W.; Huang, H.; La, D.; Lewis, R.; Liao, H.; Potashman, M.; Stellwagen, J.; Yi, S.; Norman, M.; Stec, M.; Peterson, E. A.; Graceffa, R. PCT. Int. Appl. WO2010132598, 2010.
- (2010)
- Bode, C.¹ Boezio, A.² Cheng, A.C.³ Choquette, D.⁴ Coats, J.R.⁵ Copeland, K.W.⁶ Huang, H.⁷ La, D.⁸ Lewis, R.⁹ Liao, H.¹⁰ Potashman, M.¹¹ Stellwagen, J.¹² Yi, S.¹³ Norman, M.¹⁴ Stec, M.¹⁵ Peterson, E.A.¹⁶ Graceffa, R.¹⁷

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