메뉴 건너뛰기




Volumn 17, Issue 3, 2012, Pages 324-333

Pioglitazone attenuates cardiac fibrosis and hypertrophy in a rat model of diabetic nephropathy

Author keywords

cardiac fibrosis; cardiac hypertrophy; diabetic nephropathy; pioglitazone; transforming growth factor 1

Indexed keywords

COLLAGEN FIBER; CREATINE KINASE MB; GELATINASE A; PIOGLITAZONE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84865112302     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248411431581     Document Type: Article
Times cited : (15)

References (44)
  • 1
    • 33947492733 scopus 로고    scopus 로고
    • Cardiovascular disease in diabetic nephropathy patients: Cell adhesion molecules as potential markers?
    • Wu T, McGrath KC, Death AK. Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers?. Vasc Health Risk Manag. 2005 ; 1 (4). 309-316
    • (2005) Vasc Health Risk Manag , vol.1 , Issue.4 , pp. 309-316
    • Wu, T.1    McGrath, K.C.2    Death, A.K.3
  • 2
    • 70350566099 scopus 로고    scopus 로고
    • Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function
    • Falcao-Pires I, Goncalves N, Moura C, et al. Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function. Am J Hypertens. 2009 ; 22 (11). 1190-1198
    • (2009) Am J Hypertens , vol.22 , Issue.11 , pp. 1190-1198
    • Falcao-Pires, I.1    Goncalves, N.2    Moura, C.3
  • 4
    • 35748974863 scopus 로고    scopus 로고
    • Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function
    • DOI 10.1152/physrev.00012.2007
    • Spinale FG. Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol Rev. 2007 ; 87 (4). 1285-1342 (Pubitemid 350041472)
    • (2007) Physiological Reviews , vol.87 , Issue.4 , pp. 1285-1342
    • Spinale, F.G.1
  • 5
    • 37349082926 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease
    • DOI 10.1016/j.bcp.2007.07.004, PII S000629520700425X
    • Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol. 2008 ; 75 (2). 346-359 (Pubitemid 350298459)
    • (2008) Biochemical Pharmacology , vol.75 , Issue.2 , pp. 346-359
    • Raffetto, J.D.1    Khalil, R.A.2
  • 6
    • 27244459614 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Their biological functions and clinical implications
    • Hijova E. Matrix metalloproteinases: their biological functions and clinical implications. Bratisl Lek Listy. 2005 ; 106 (3). 127-132
    • (2005) Bratisl Lek Listy , vol.106 , Issue.3 , pp. 127-132
    • Hijova, E.1
  • 8
    • 32644448320 scopus 로고    scopus 로고
    • The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy
    • DOI 10.1016/j.jacc.2005.09.050, PII S0735109705027476
    • Asbun J, Villarreal FJ. The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy. J Am Coll Cardiol. 2006 ; 47 (4). 693-700 (Pubitemid 43243087)
    • (2006) Journal of the American College of Cardiology , vol.47 , Issue.4 , pp. 693-700
    • Asbun, J.1    Villarreal, F.J.2
  • 9
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Jarvinen H. Thiazolidinediones. N Engl J Med. 2004 ; 351 (11). 1106-1118
    • (2004) N Engl J Med , vol.351 , Issue.11 , pp. 1106-1118
    • Yki-Jarvinen, H.1
  • 10
    • 33845447260 scopus 로고    scopus 로고
    • Cardiovascular disease prevention in patients with type 2 diabetes: The role of oral anti-diabetic agents
    • DOI 10.3132/dvdr.2006.023
    • Ajjan RA, Grant PJ. Cardiovascular disease prevention in patients with type 2 diabetes: the role of oral anti-diabetic agents. Diab Vasc Dis Res. 2006 ; 3 (3). 147-158 (Pubitemid 44902480)
    • (2006) Diabetes and Vascular Disease Research , vol.3 , Issue.3 , pp. 147-158
    • Ajjan, R.A.1    Grant, P.J.2
  • 11
    • 67449103220 scopus 로고    scopus 로고
    • Redefining the role of thiazolidinediones in the management of type 2 diabetes
    • Barnett AH. Redefining the role of thiazolidinediones in the management of type 2 diabetes. Vasc Health Risk Manag. 2009 ; 5 (1). 141-151
    • (2009) Vasc Health Risk Manag , vol.5 , Issue.1 , pp. 141-151
    • Barnett, A.H.1
  • 13
    • 41549083695 scopus 로고    scopus 로고
    • Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension
    • DOI 10.1291/hypres.31.325
    • Polizio AH, Balestrasse KB, Yannarelli GG, et al. Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension. Hypertens Res. 2008 ; 31 (2). 325-334 (Pubitemid 351461113)
    • (2008) Hypertension Research , vol.31 , Issue.2 , pp. 325-334
    • Polizio, A.H.1    Balestrasse, K.B.2    Yannarelli, G.G.3    Noriega, G.O.4    Gorzalczany, S.5    Taira, C.6    Tomaro, M.L.7
  • 14
    • 0014478342 scopus 로고
    • Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen
    • Trinder P. Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J Clin Pathol. 1969 ; 22 (2). 158-161
    • (1969) J Clin Pathol , vol.22 , Issue.2 , pp. 158-161
    • Trinder, P.1
  • 15
    • 0018581679 scopus 로고
    • Creatine kinase B-subunit activity in serum after immumoinhibition of M-subunit activity
    • Gerhardt W, Waldenstrom J. Creatine kinase B-subunit activity in serum after immunoinhibition of M-subunit activity. Clin Chem. 1979 ; 25 (7). 1274-1280 (Pubitemid 9253240)
    • (1979) Clinical Chemistry , vol.25 , Issue.7 , pp. 1274-1280
    • Gerhardt, W.1    Waldenstrom, J.2
  • 16
    • 0014258678 scopus 로고
    • Estimation of creatinine by the Jaffe reaction. A comparison of three methods
    • Husdan H, Rapoport A.. Estimation of creatinine by the Jaffe reaction. A comparison of three methods. Clin Chem. 1968 ; 14 (3). 222-238
    • (1968) Clin Chem , vol.14 , Issue.3 , pp. 222-238
    • Husdan, H.1    Rapoport, A.2
  • 17
    • 41549106626 scopus 로고    scopus 로고
    • Pioglitazone, a thiazolidinedione derivative, attenuates left ventricular hypertrophy and fibrosis in salt-sensitive hypertension
    • DOI 10.1291/hypres.31.353
    • Nakamoto M, Ohya Y, Shinzato T, et al. Pioglitazone, a thiazolidinedione derivative, attenuates left ventricular hypertrophy and fibrosis in salt-sensitive hypertension. Hypertens Res. 2008 ; 31 (2). 353-361 (Pubitemid 351461116)
    • (2008) Hypertension Research , vol.31 , Issue.2 , pp. 353-361
    • Nakamoto, M.1    Ohya, Y.2    Shinzato, T.3    Mano, R.4    Yamazato, M.5    Sakima, A.6    Takishita, S.7
  • 18
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979 ; 95 (2). 351-358 (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 19
    • 53149108960 scopus 로고    scopus 로고
    • Cardiovascular disease in patients with diabetic nephropathy
    • Aso Y. Cardiovascular disease in patients with diabetic nephropathy. Curr Mol Med. 2008 ; 8 (6). 533-543
    • (2008) Curr Mol Med , vol.8 , Issue.6 , pp. 533-543
    • Aso, Y.1
  • 20
    • 43249101701 scopus 로고    scopus 로고
    • Advanced glycation and ROS: A link between diabetes and heart failure
    • Rojas A, Mercadal E, Figueroa H, Morales MA. Advanced glycation and ROS: a link between diabetes and heart failure. Curr Vasc Pharmacol. 2008 ; 6 (1). 44-51
    • (2008) Curr Vasc Pharmacol , vol.6 , Issue.1 , pp. 44-51
    • Rojas, A.1    Mercadal, E.2    Figueroa, H.3    Morales, M.A.4
  • 22
    • 69249106093 scopus 로고    scopus 로고
    • Cardioprotective effect of vitamin E: Rescues of diabetes-induced cardiac malfunction, oxidative stress, and apoptosis in rat
    • Shirpoor A, Salami S, Khadem-Ansari MH, et al. Cardioprotective effect of vitamin E: rescues of diabetes-induced cardiac malfunction, oxidative stress, and apoptosis in rat. J Diabetes Complications. 2009 ; 23 (5). 310-316
    • (2009) J Diabetes Complications , vol.23 , Issue.5 , pp. 310-316
    • Shirpoor, A.1    Salami, S.2    Khadem-Ansari, M.H.3
  • 23
    • 70350700901 scopus 로고    scopus 로고
    • Oxidative stress, diabetes, and diabetic complications
    • Wei W, Liu Q, Tan Y, Liu L, Li X, Cai L. Oxidative stress, diabetes, and diabetic complications. Hemoglobin. 2009 ; 33 (5). 370-377
    • (2009) Hemoglobin , vol.33 , Issue.5 , pp. 370-377
    • Wei, W.1    Liu, Q.2    Tan, Y.3    Liu, L.4    Li, X.5    Cai, L.6
  • 24
    • 41749123049 scopus 로고    scopus 로고
    • Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: Role in extracellular matrix production
    • Singh VP, Baker KM, Kumar R. Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production. Am J Physiol Heart Circ Physiol. 2008 ; 294 (4). H1675 - H1684
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , Issue.4
    • Singh, V.P.1    Baker, K.M.2    Kumar, R.3
  • 25
    • 37549058838 scopus 로고    scopus 로고
    • Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats
    • Aragno M, Mastrocola R, Alloatti G, et al. Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats. Endocrinology. 2008 ; 149 (1). 380-388
    • (2008) Endocrinology , vol.149 , Issue.1 , pp. 380-388
    • Aragno, M.1    Mastrocola, R.2    Alloatti, G.3
  • 26
    • 0034162004 scopus 로고    scopus 로고
    • Cardiac remodeling-concepts and clinical implications: A consensus paper from an International Forum on Cardiac Remodeling
    • DOI 10.1016/S0735-1097(99)00630-0, PII S0735109799006300
    • Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling. J Am Coll Cardiol. 2000 ; 35 (3). 569-582 (Pubitemid 30167013)
    • (2000) Journal of the American College of Cardiology , vol.35 , Issue.3 , pp. 569-582
    • Cohn, J.N.1    Ferrari, R.2    Sharpe, N.3
  • 27
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: At the heart of myocardial remodeling
    • Porter KE, Turner NA. Cardiac fibroblasts: at the heart of myocardial remodeling. Pharmacol Ther. 2009 ; 123 (2). 255-278
    • (2009) Pharmacol Ther , vol.123 , Issue.2 , pp. 255-278
    • Porter, K.E.1    Turner, N.A.2
  • 28
    • 0036166524 scopus 로고    scopus 로고
    • Physiologic and pathologic myocardial hypertrophy - Physiologic and pathologic regression of hypertrophy?
    • DOI 10.1054/mehy.2001.1399
    • Simko F. Physiologic and pathologic myocardial hypertrophy-physiologic and pathologic regression of hypertrophy?. Med Hypotheses. 2002 ; 58 (1). 11-14 (Pubitemid 34136721)
    • (2002) Medical Hypotheses , vol.58 , Issue.1 , pp. 11-14
    • Simko, F.1
  • 29
    • 58149328554 scopus 로고    scopus 로고
    • Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis
    • Singh VP, Le B, Khode R, Baker KM, Kumar R. Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes. 2008 ; 57 (12). 3297-3306
    • (2008) Diabetes , vol.57 , Issue.12 , pp. 3297-3306
    • Singh, V.P.1    Le, B.2    Khode, R.3    Baker, K.M.4    Kumar, R.5
  • 30
    • 34547892633 scopus 로고    scopus 로고
    • Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts
    • Wang B, Omar A, Angelovska T, et al. Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts. Am J Physiol Heart Circ Physiol. 2007 ; 293 (2). H1282 - H1290
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , Issue.2
    • Wang, B.1    Omar, A.2    Angelovska, T.3
  • 31
    • 46149083476 scopus 로고    scopus 로고
    • Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy
    • Van Linthout S, Seeland U, Riad A, et al. Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy. Basic Res Cardiol. 2008 ; 103 (4). 319-327
    • (2008) Basic Res Cardiol , vol.103 , Issue.4 , pp. 319-327
    • Van Linthout, S.1    Seeland, U.2    Riad, A.3
  • 32
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • DOI 10.1161/01.RES.0000070112.80711.3D
    • Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res. 2003 ; 92 (8). 827-839 (Pubitemid 36542523)
    • (2003) Circulation Research , vol.92 , Issue.8 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 33
    • 12344305994 scopus 로고    scopus 로고
    • Heterogeneous effects of tissue inhibitors of matrix metalloproteinases on cardiac fibroblasts
    • Lovelock JD, Baker AH, Gao F, et al. Heterogeneous effects of tissue inhibitors of matrix metalloproteinases on cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 2005 ; 288 (2). H461 - H468
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , Issue.2
    • Lovelock, J.D.1    Baker, A.H.2    Gao, F.3
  • 34
    • 35348881447 scopus 로고    scopus 로고
    • The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats
    • DOI 10.2143/AC.62.5.2023412
    • Li Q, Sun SZ, Wang Y, Tian YJ, Liu MH. The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats. Acta Cardiol. 2007 ; 62 (5). 485-491 (Pubitemid 47582641)
    • (2007) Acta Cardiologica , vol.62 , Issue.5 , pp. 485-491
    • Li, Q.1    Sun, S.-Z.2    Wang, Y.3    Tian, Y.-J.4    Liu, M.-H.5
  • 35
    • 33846069095 scopus 로고    scopus 로고
    • Thiazolidinediones for the treatment of type 2 diabetes
    • DOI 10.1016/j.ejim.2006.09.007, PII S0953620506002573
    • Elte JW, Blickle JF. Thiazolidinediones for the treatment of type 2 diabetes. Eur J Intern Med. 2007 ; 18 (1). 18-25 (Pubitemid 46072729)
    • (2007) European Journal of Internal Medicine , vol.18 , Issue.1 , pp. 18-25
    • Elte, J.W.F.1    Blickle, J.F.2
  • 36
    • 33748983516 scopus 로고    scopus 로고
    • The direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta
    • DOI 10.1016/j.ejphar.2006.08.036, PII S0014299906008843
    • Toba H, Miki S, Shimizu T, et al. The direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta. Eur J Pharmacol. 2006 ; 549 (1-3). 124-132 (Pubitemid 44441265)
    • (2006) European Journal of Pharmacology , vol.549 , Issue.1-3 , pp. 124-132
    • Toba, H.1    Miki, S.2    Shimizu, T.3    Yoshimura, A.4    Inoue, R.5    Sawai, N.6    Tsukamoto, R.7    Murakami, M.8    Morita, Y.9    Nakayama, Y.10    Kobara, M.11    Nakata, T.12
  • 37
    • 14644393603 scopus 로고    scopus 로고
    • Effects of pioglitazone on hyperglycemia-induced alterations in antioxidative system in tissues of alloxan-treated diabetic animals
    • DOI 10.1016/j.etp.2004.12.002
    • Gumieniczek A. Effects of pioglitazone on hyperglycemia-induced alterations in antioxidative system in tissues of alloxan-treated diabetic animals. Exp Toxicol Pathol. 2005 ; 56 (4-5). 321-326 (Pubitemid 40312757)
    • (2005) Experimental and Toxicologic Pathology , vol.56 , Issue.4-5 , pp. 321-326
    • Gumieniczek, A.1
  • 39
    • 75149120650 scopus 로고    scopus 로고
    • Potentiation by candesartan of protective effects of pioglitazone against type 2 diabetic cardiovascular and renal complications in obese mice
    • Fukuda M, Nakamura T, Kataoka K, et al. Potentiation by candesartan of protective effects of pioglitazone against type 2 diabetic cardiovascular and renal complications in obese mice. J Hypertens. 2010 ; 28 (2). 340-352
    • (2010) J Hypertens , vol.28 , Issue.2 , pp. 340-352
    • Fukuda, M.1    Nakamura, T.2    Kataoka, K.3
  • 40
    • 7244229584 scopus 로고    scopus 로고
    • Angiotensin II regulation of collagen type I expression in cardiac fibroblasts: Modulation by PPAR-γ ligand pioglitazone
    • DOI 10.1161/01.HYP.0000144400.49062.6b
    • Chen K, Chen J, Li D, Zhang X, Mehta JL. Angiotensin II regulation of collagen type I expression in cardiac fibroblasts: modulation by PPAR-gamma ligand pioglitazone. Hypertension. 2004 ; 44 (5). 655-661 (Pubitemid 39435235)
    • (2004) Hypertension , vol.44 , Issue.5 , pp. 655-661
    • Chen, K.1    Chen, J.2    Li, D.3    Zhang, X.4    Mehta, J.L.5
  • 41
    • 24044476859 scopus 로고    scopus 로고
    • Cardiomyocyte-specffic knockout and agonist of peroxisome proliferator-activated receptor-γ both induce cardiac hypertrophy in mice
    • DOI 10.1161/01.RES.0000179226.34112.6d
    • Duan SZ, Ivashchenko CY, Russell MW, Milstone DS, Mortensen RM. Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice. Circ Res. 2005 ; 97 (4). 372-379 (Pubitemid 41216142)
    • (2005) Circulation Research , vol.97 , Issue.4 , pp. 372-379
    • Duan, S.Z.1    Ivashchenko, C.Y.2    Russell, M.W.3    Milstone, D.S.4    Mortensen, R.M.5
  • 42
    • 0037058874 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor-γ agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • DOI 10.1161/01.CIR.0000039346.31538.2C
    • Shiomi T, Tsutsui H, Hayashidani S, et al. Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation. 2002 ; 106 (24). 3126-3132 (Pubitemid 35440299)
    • (2002) Circulation , vol.106 , Issue.24 , pp. 3126-3132
    • Shiomi, T.1    Tsutsui, H.2    Hayashidani, S.3    Suematsu, N.4    Ikeuchi, M.5    Wen, J.6    Ishibashi, M.7    Kubota, T.8    Egashira, K.9    Takeshita, A.10
  • 43
    • 33645280925 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: The search for a unifying hypothesis
    • Poornima IG, Parikh P, Shannon RP. Diabetic cardiomyopathy: the search for a unifying hypothesis. Circ Res. 2006 ; 98 (5). 596-605
    • (2006) Circ Res , vol.98 , Issue.5 , pp. 596-605
    • Poornima, I.G.1    Parikh, P.2    Shannon, R.P.3
  • 44
    • 77957606875 scopus 로고    scopus 로고
    • Effects of metformin on rosiglitazone-induced cardiac hypertrophy in mice
    • Lee HH, Yeh CH, Chen YT, et al. Effects of metformin on rosiglitazone-induced cardiac hypertrophy in mice. Biol Pharm Bull. 2010 ; 33 (9). 1506-1510
    • (2010) Biol Pharm Bull , vol.33 , Issue.9 , pp. 1506-1510
    • Lee, H.H.1    Yeh, C.H.2    Chen, Y.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.