Increased d-dimer levels predict cardiovascular mortality in patients with systolic heart failure

Journal of Thrombosis and Thrombolysis

Volumn 33, Issue 4, 2012, Pages 322-328

  Zorlu, Ali ^a   Yilmaz, Mehmet Birhan ^a   Yucel, Hasan ^a   Bektasoglu, Gokhan ^a   Ege, Meltem Refiker ^b   Tandogan, Izzet ^a  

^a CUMHURIYET UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b Yalova Devlet Hastanesi   (Turkey)

Author keywords

Cardiovascular mortality; D dimer; Heart failure; Risk stratification

Indexed keywords

CREATININE; D DIMER; FIBRIN DEGRADATION PRODUCT; FIBRIN FRAGMENT D;

AGE; AGED; ARTICLE; CARDIOVASCULAR MORTALITY; CAUSE OF DEATH; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; FEMALE; HEART ATRIUM FIBRILLATION; HEART EJECTION FRACTION; HEART LEFT ATRIUM; HEART LEFT VENTRICLE SIZE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; REFERENCE VALUE; RISK ASSESSMENT; SURVIVAL RATE; SYSTOLIC HEART FAILURE; BLOOD; CLINICAL TRIAL; FOLLOW UP; HEART STROKE VOLUME; METABOLISM; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; RISK FACTOR;

AGED; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FOLLOW-UP STUDIES; HEART FAILURE, SYSTOLIC; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; STROKE VOLUME; SURVIVAL RATE;

EID: 84865108006     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-011-0635-0     Document Type: Article

References (26)

1. Goldberg RJ, Ciampa J, Lessard D, Meyer TE, Spencer FA (2007) Long-term survival after heart failure: a contemporary population-based perspective. Arch Intern Med 167(5):490-496
2. Gheorghiade M, Pang PS (2009) Acute heart failure syndromes. J Am Coll Cardiol 53(7):557-573
3. Zoghi M, Duygu H, Gungor H, Nalbantgil S, Yilmaz GM, Tuluce K et al (2008) The determination of the factors impacting on inhospital mortality in patients with acute heart failure in a tertiary referral center. Anadolu Kardiyol Derg 8(4):255-259
4. O'Connor CM, Hasselblad V, Mehta RH, Tasissa G, Califf RM, Fiuzat M et al (2010) Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score. J Am Coll Cardiol 55(9):872-878
5. Darze ES, Latado AL, Guimaraes AG, Guedes RA, Santos AB, de Moura SS et al (2007) Acute pulmonary embolism is an independent predictor of adverse events in severe decompensated heart failure patients. Chest 131(6):1838-1843
6. Ng TM, Tsai F, Khatri N, Barakat MN, Elkayam U (2010) Venous thromboembolism in hospitalized patients with heart failure: incidence, prognosis, and prevention. Circ Heart Fail 3(1):165-173
7. Qasim A, Duggan M, O'Connell N, O'Driscoll A (2009) Clinical conditions and patient factors significantly influence diagnostic utility of D-dimer in venous thromboembolism. Blood Coagul Fibrinolysis 20(4):244-247
8. Sohne M, Kruip MJ, Nijkeuter M, Tick L, Kwakkel H, Halkes SJ et al (2006) Accuracy of clinical decision rule, D-dimer and spiral computed tomography in patients with malignancy, previous venous thromboembolism, COPD or heart failure and in older patients with suspected pulmonary embolism. J Thromb Haemost 4(5):1042-1046
9. Tan M, Huisman MV (2010) Point-of-care D-dimer tests can contribute to patient management in outpatients with suspected venous thromboembolism, particularly those at low risk. Evid Based Med 15(1):28
10. Nieminen MS, Bohm M, Cowie MR, Drexler H, Filippatos GS, Jondeau G et al (2005) Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology. Eur Heart J 26(4):384-416
11. Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA et al (2008) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 29(19): 2388-2442
12. Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galié N, Pruszczyk P et al (2008) Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 29(18): 2276-2315
13. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA et al (2006) Recommendations for chamber quantification. Eur J Echocardiogr 7(2):79-108
14. Koracevic GP (2009) Pragmatic classification of the causes of high D-dimer. Am J Emerg Med 27(8):1016, e1015-1016, e1017
15. Cosmi B, Legnani C, Iorio A, Pengo V, Ghirarduzzi A, Testa S et al (2010) Residual venous obstruction, alone and in combination with D-dimer, as a risk factor for recurrence after anticoagulation withdrawal following a first idiopathic deep vein thrombosis in the prolong study. Eur J Vasc Endovasc Surg 39(3): 356-365
16. Morange PE, Bickel C, Nicaud V, Schnabel R, Rupprecht HJ, Peetz D et al (2006) Haemostatic factors and the risk of cardiovascular death in patients with coronary artery disease: the AtheroGene study. Arterioscler Thromb Vasc Biol 26(12):2793-2799
17. Oke M, Koppensteiner R, Schillinger M, Haumer M, Minar E, Wiesbauer F et al (2010) D-dimer testing in the diagnosis of transfemoral pseudoaneurysm after percutaneous transluminal procedures. J Vasc Surg 52(2):383-387
18. Tarnow I, Falk T, Tidholm A, Martinussen T, Jensen AL, Olsen LH et al (2007) Hemostatic biomarkers in dogs with chronic congestive heart failure. J Vet Intern Med 21(3):451-457
19. Jug B, Vene N, Salobir BG, Sebestjen M, Sabovic M, Keber I (2009) Prognostic impact of haemostatic derangements in chronic heart failure. Thromb Haemost 102(2):314-320
20. Alehagen U, Dahlstrom U, Lindahl TL (2004) Elevated D-dimer level is an independent risk factor for cardiovascular death in outpatients with symptoms compatible with heart failure. Thromb Haemost 92(6):1250-1258
21. Pullicino PM, Halperin JL, Thompson JL (2000) Stroke in patients with heart failure and reduced left ventricular ejection fraction. Neurology 54(2):288-294
22. Siachos T, Vanbakel A, Feldman DS, Uber W, Simpson KN, Pereira NL (2005) Silent strokes in patients with heart failure. J Card Fail 11(7):485-489
23. Dotsenko O, Kakkar VV (2007) Antithrombotic therapy in patients with chronic heart failure: rationale, clinical evidence and practical implications. J Thromb Haemost 5(2):224-231
24. Yusuf S, Pepine CJ, Garces C, Pouleur H, Salem D, Kostis J et al (1992) Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions. Lancet 340(8829): 1173-1178
25. Bittencourt and colleagues (2005) Abstract from third international symposium on intensive care and emergency medicine for Latin America Sao Paulo, Brazil. June 22-25 Critical Care 9 (Suppl 2):P29)
26. Marcucci R, Gori AM, Giannotti F, Baldi M, Verdiani V, Del Pace S et al (2006) Markers of hypercoagulability and inflammation predict mortality in patients with heart failure. J Thromb Haemost 4(5):1017-1022