Clinical conditions and patient factors significantly influence diagnostic utility of D-dimer in venous thromboembolism

Blood Coagulation and Fibrinolysis

Volumn 20, Issue 4, 2009, Pages 244-247

  Qasim, Asghar ^a,b   Duggan, Mary ^a   O'Connell, Niamh ^a   O'Driscoll, Anne ^a  

^a Naas General Hospital   (Ireland)

^b ADELAIDE AND MEATH HOSPITAL   (Ireland)

Author keywords

Abnormal chest radiography; Age; Compression ultrasonography; D dimer; Deep venous thrombosis; High resolution computerized tomography; Immunoturbidometry; Neoplasia; Pulmonary angiography; Pulmonary embolism

Indexed keywords

D DIMER;

ADULT; ARTICLE; BLOOD SAMPLING; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; DIAGNOSTIC VALUE; ECHOGRAPHY; EMERGENCY WARD; FALSE POSITIVE RESULT; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; KIDNEY FAILURE; KIDNEY FUNCTION; LUNG ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; THORAX RADIOGRAPHY; VENOUS THROMBOEMBOLISM;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANGIOGRAPHY; EMERGENCY SERVICE, HOSPITAL; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; KIDNEY DISEASES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; ULTRASONOGRAPHY; VENOUS THROMBOEMBOLISM;

EID: 67649549980     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328325600f     Document Type: Article

References (23)

1. Kline JA, Johns KL, Colucciello SA, Israel EG. New diagnostic tests for pulmonary embolism. Ann Emerg Me. 2000; 35:168-180.
2. Elhabyan A, Broce M, Rosencrance JG, Lucas BD, Nakker S, Reyes BJ. The quantitative immunoturbidimetric D-dimer method to rule out venous thromboembolism (VTE). W V Med. 2007; 103:22-25.
3. Crowther MA, Cook DJ, Griffith LE. Neither baseline tests of molecular hypercoagulability nor D-dimer levels predict deep venous thrombosis in critically ill medical-surgical patients. Intensive Care Me. 2005; 31:48- 55.
4. Farrell S, Hayes T, Shaw M. A negative SimphRED D-dimer assay result does not exclude the diagnosis of deep vein thrombosis or pulmonary embolus in emergency department patients. Ann Emerg Me. 2000; 35:121-125.
5. Qaseem A, Snow V, Barry P. Current diagnosis of venous thromboembolism in primary care: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians. Ann Fam Me. 2007; 5:57-62.
6. British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development Group. British Thoracic Guidelines for the management of suspected acute pulmonary embolism. Thora. 2003; 58:470-483.
7. Wells PS, Anderson DR, Bormanis J. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lance. 1997; 350:1795-1798.
8. Stein PD, Hull RD, Patel KC. D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. Ann Intern Me. 2004; 140:589-602.
9. Prologo JD, Glauser J. Variable diagnostic approach to suspected pulmonary embolism in the ED of a major academic tertiary care center. Am J Emerg Me. 2002; 20:5-9.
10. Lemb M, Pohlobeln H. Pulmonary thromboembolism: a retrospective study on the examination of 991 patients by ventilation/perfusion SPECT using Technigas. Nucl Me. 2001; 40:179-186.
11. Itti E, Neuyen S, Robin F, Desarnaud S, Rosso J, Harf A, Meignan M. Distribution of ventilation/perfusion ratios in pulmonary embolism: an adjunct to the interpretation of ventilation/perfusion lung scans. J Nucl Me. 2002;43:1596-1602.
12. Berghout A, Oudkerk M, Hicks SG, Teng TH, Pillay M, Buller HR. Active implementation of a consensus strategy improves diagnosis and management in suspected pulmonary embolism. QJ. 2000; 93:335-340.
13. Stein PD, Athanasoulis C, Alavi A. Complications and validity of pulmonary angiography in acute pulmonary embolism. Circulatio. 1992; 85:462- 468.
14. Van Beek EJ, Brouwers EM, Song B, Bongaerts AH, Qudkerk M. Lung scintigraphy and lelical computed tomography for the diagnosis of pulmonary embolism: a meta-analysis. Clin Appl Thromb Hem. 2001; 7:87-92.
15. Hartmann I, Hagen P, Melissant C, Postmus PE, Prins MH. Diagnosing acute pulmonary embolism: effect of chronic obstructive pulmonary disease on the performance of D-dimer testing, ventilation/perfusion scintigraphy, spiral computed tomographic angiography, and conventional angiography. ANTELOPE Study Group. Advances in New Technologies Evaluating the Localization of Pulmonary Embolism. Am J Respir Crit Care Me. 2000; 162:2232-2237.
16. Wilson HT, Meagher TM, Williams SJ. Combined helical computed tomographic pulmonary angiography and lung perfusion scintigraphy for investigating acute pulmonary embolim. Clin Radio. 2002; 57:33-36.
17. Rosen MP, Sands DZ, Morris J, Drake W, Davis RB. Does a physician's ability to accurately assess the likelihood of pulmonary embolism increase with training? Acad Me. 2000; 75:1199-1205.
18. lio A, Rutherford WE, Wochner RD, Spilberg I, Sherman LA. The roles of renal catabolism and uremia in modifying the clearance of fibrinogen and its degradative fragments D and E. Lab Clin Me. 1976 87:934-946.
19. Lane DA, Ireland H, Kinght I, Wolff S, Kyle P, Curtis JR. The significance of fibrinogen derivatives in plasma in human renal failure. Br J Haemato. 1984; 56:251-260.
20. George MP, Faint RW, Rylance PB, Ireland H, Lane DA, Neild GH. Plasma D dimer: a useful marker of fibrin breakdown in renal failure. Thromb Haemos. 1989; 61:522-525.
21. Castro DJ, Perez-Rodriguez E, Montaner L, Flores J, Nuevo DG. Diagnostic value of D-dimer in pulmonary embolism and pneumnia. Circulatio. 2001; 68:371 -375.
22. Sechi LA, Zingaro L, Catena C, De Marchi S. Increased fibrinogen levels and hemostatic abnormalities in patients with arteriolar nephrosclerosis: association with cardiovascular events. Thromb Haemos. 2000; 84:565- 570.
23. Philip-Joet F, Alessi MC, Philip-Joet C, Aillaud M, Barriere JR, Arnaud A, Juhan-Vague I. Fibrinolytic and inflammatory processes in pleural effusions. Eur Respir. 1995; 8:1352-1356.