Transcriptional abnormalities of hamstring muscle contractures in children with cerebral palsy

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Smith, Lucas R ^a   Chambers, Henry G ^b,c   Subramaniam, Shankar ^a   Lieber, Richard L ^a,c,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b RADY CHILDREN'S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN PROTEIN LIGASE;

ADOLESCENT; ARTICLE; BIOMECHANICS; CEREBRAL PALSY; CHILD; CLINICAL ARTICLE; DATA SYNTHESIS; EXTRACELLULAR MATRIX; FEMALE; GENE ACTIVITY; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE FUNCTION; GENETIC ALGORITHM; GENETIC CONSERVATION; GENETIC CORRELATION; GRACILIS MUSCLE; HAMSTRING; HUMAN; HUMAN TISSUE; MALE; METABOLIC REGULATION; MUSCLE BIOPSY; MUSCLE CONTRACTURE; NEUROPATHOLOGY; PASSIVE MOVEMENT; PRESCHOOL CHILD; SCHOOL CHILD; SEMITENDINOUS MUSCLE; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

ADAPTATION, PHYSIOLOGICAL; ADOLESCENT; CASE-CONTROL STUDIES; CEREBRAL PALSY; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; CONTRACTURE; FEMALE; HUMANS; LEG; MALE; MUSCLE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84865097987     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040686     Document Type: Article

References (60)

1. Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, et al. (2007) A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurol Suppl 109: 8-14.
2. Reddihough DS, Collins KJ, (2003) The epidemiology and causes of cerebral palsy. Aust J Physiother 49: 7-12.
3. Yeargin-Allsopp M, Van Naarden Braun K, Doernberg NS, Benedict RE, Kirby RS, et al. (2008) Prevalence of cerebral palsy in 8-year-old children in three areas of the United States in 2002: a multisite collaboration. Pediatrics 121: 547-554.
4. Kerr Graham H, Selber P, (2003) Musculoskeletal aspects of cerebral palsy. J Bone Joint Surg Br 85: 157-166.
5. Crenna P, (1998) Spasticity and 'spastic' gait in children with cerebral palsy. Neurosci Biobehav Rev 22: 571-578.
6. Kim WH, Park EY, (2011) Causal relation between spasticity, strength, gross motor function, and functional outcome in children with cerebral palsy: a path analysis. Dev Med Child Neurol 53: 68-73.
7. Lin JP, (2011) The contribution of spasticity to the movement disorder of cerebral palsy using pathway analysis: does spasticity matter? Dev Med Child Neurol 53: 7-9.
8. Bache CE, Selber P, Graham HK, (2003) (ii) The management of spastic diplegia. Current Orthopaedics 17: 88-104.
9. Koman LA, Smith BP, Shilt JS, (2004) Cerebral palsy. Lancet 363: 1619-1631.
10. Tilton AH, (2006) Therapeutic interventions for tone abnormalities in cerebral palsy. NeuroRx 3: 217-224.
11. Hankins GD, Speer M, (2003) Defining the pathogenesis and pathophysiology of neonatal encephalopathy and cerebral palsy. Obstet Gynecol 102: 628-636.
12. Foran JR, Steinman S, Barash I, Chambers HG, Lieber RL, (2005) Structural and mechanical alterations in spastic skeletal muscle. Dev Med Child Neurol 47: 713-717.
13. Lorentzen J, Grey MJ, Crone C, Mazevet D, Biering-Sorensen F, et al. (2010) Distinguishing active from passive components of ankle plantar flexor stiffness in stroke, spinal cord injury and multiple sclerosis. Clin Neurophysiol.
14. Sinkjaer T, Magnussen I, (1994) Passive, intrinsic and reflex-mediated stiffness in the ankle extensors of hemiparetic patients. Brain 117 (Pt 2): 355-363.
15. Smith LR, Lee KS, Ward SR, Chambers HG, Lieber RL, (2011) Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length. The Journal of physiology 589: 2625-2639.
16. Lieber RL, Friden J, (2002) Spasticity causes a fundamental rearrangement of muscle-joint interaction. Muscle Nerve 25: 265-270.
17. Malaiya R, McNee AE, Fry NR, Eve LC, Gough M, et al. (2007) The morphology of the medial gastrocnemius in typically developing children and children with spastic hemiplegic cerebral palsy. J Electromyogr Kinesiol 17: 657-663.
18. Mohagheghi AA, Khan T, Meadows TH, Giannikas K, Baltzopoulos V, et al. (2007) Differences in gastrocnemius muscle architecture between the paretic and non-paretic legs in children with hemiplegic cerebral palsy. Clin Biomech (Bristol, Avon) 22: 718-724.
19. Mohagheghi AA, Khan T, Meadows TH, Giannikas K, Baltzopoulos V, et al. (2008) In vivo gastrocnemius muscle fascicle length in children with and without diplegic cerebral palsy. Dev Med Child Neurol 50: 44-50.
20. Shortland AP, Harris CA, Gough M, Robinson RO, (2002) Architecture of the medial gastrocnemius in children with spastic diplegia. Dev Med Child Neurol 44: 158-163.
21. Elder GC, Kirk J, Stewart G, Cook K, Weir D, et al. (2003) Contributing factors to muscle weakness in children with cerebral palsy. Dev Med Child Neurol 45: 542-550.
22. Rose J, McGill KC, (2005) Neuromuscular activation and motor-unit firing characteristics in cerebral palsy. Dev Med Child Neurol 47: 329-336.
23. Stackhouse SK, Binder-Macleod SA, Lee SC, (2005) Voluntary muscle activation, contractile properties, and fatigability in children with and without cerebral palsy. Muscle Nerve 31: 594-601.
24. Smith LR, Ponten E, Hedstrom Y, Ward SR, Chambers HG, et al. (2009) Novel transcriptional profile in wrist muscles from cerebral palsy patients. BMC Med Genomics 2: 44.
25. Feltrin E, Campanaro S, Diehl AD, Ehler E, Faulkner G, et al. (2009) Muscle Research and Gene Ontology: New standards for improved data integration. BMC Med Genomics 2: 6.
26. Klebanov L, Qiu X, Welle S, Yakovlev A, (2007) Statistical methods and microarray data. Nature biotechnology 25: 25-26; author reply 26-27.
27. Booth CM, Cortina-Borja MJ, Theologis TN, (2001) Collagen accumulation in muscles of children with cerebral palsy and correlation with severity of spasticity. Developmental medicine and child neurology 43: 314-320.
28. Lieber RL, Runesson E, Einarsson F, Friden J, (2003) Inferior mechanical properties of spastic muscle bundles due to hypertrophic but compromised extracellular matrix material. Muscle & nerve 28: 464-471.
29. Friden J, Lieber RL, (2003) Spastic muscle cells are shorter and stiffer than normal cells. Muscle & nerve 27: 157-164.
30. Barrett RS, Lichtwark GA, (2010) Gross muscle morphology and structure in spastic cerebral palsy: a systematic review. Developmental medicine and child neurology 52: 794-804.
31. Theroux MC, Akins RE, Barone C, Boyce B, Miller F, et al. (2002) Neuromuscular junctions in cerebral palsy: presence of extrajunctional acetylcholine receptors. Anesthesiology 96: 330-335.
32. Tsay HJ, Schmidt J, (1989) Skeletal muscle denervation activates acetylcholine receptor genes. The Journal of cell biology 108: 1523-1526.
33. Verrotti A, Greco R, Spalice A, Chiarelli F, Iannetti P, (2006) Pharmacotherapy of spasticity in children with cerebral palsy. Pediatric neurology 34: 1-6.
34. Schiaffino S, Reggiani C, (1996) Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiological reviews 76: 371-423.
35. Olive M, Shatunov A, Gonzalez L, Carmona O, Moreno D, et al. (2008) Transcription-terminating mutation in telethonin causing autosomal recessive muscular dystrophy type 2G in a European patient. Neuromuscular disorders: NMD 18: 929-933.
36. Brown CA, Scharner J, Felice K, Meriggioli MN, Tarnopolsky M, et al. (2011) Novel and recurrent EMD mutations in patients with Emery-Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot. Journal of human genetics.
37. Maraldi NM, Capanni C, Del Coco R, Squarzoni S, Columbaro M, et al. (2011) Muscular laminopathies: role of prelamin A in early steps of muscle differentiation. Advances in enzyme regulation 51: 246-256.
38. Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, et al. (2007) Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. The Journal of biological chemistry 282: 25852-25863.
39. Ivanhoe CB, Reistetter TA, (2004) Spasticity: the misunderstood part of the upper motor neuron syndrome. American journal of physical medicine & rehabilitation/Association of Academic Physiatrists 83: S3-9.
40. Pohl M, Mehrholz J, Rockstroh G, Ruckriem S, Koch R, (2007) Contractures and involuntary muscle overactivity in severe brain injury. Brain injury: [BI] 21: 421-432.
41. Smith C, Kruger MJ, Smith RM, Myburgh KH, (2008) The inflammatory response to skeletal muscle injury: illuminating complexities. Sports medicine 38: 947-969.
42. Tardieu C, Huet de la Tour E, Bret MD, Tardieu G, (1982) Muscle hypoextensibility in children with cerebral palsy: I. Clinical and experimental observations. Archives of physical medicine and rehabilitation 63: 97-102.
43. Tardieu G, Tardieu C, Colbeau-Justin P, Lespargot A, (1982) Muscle hypoextensibility in children with cerebral palsy: II. Therapeutic implications. Archives of physical medicine and rehabilitation 63: 103-107.
44. Clavet H, Hebert PC, Fergusson D, Doucette S, Trudel G, (2008) Joint contracture following prolonged stay in the intensive care unit. CMAJ: Canadian Medical Association journal = journal de l'Association medicale canadienne 178: 691-697.
45. Husmann I, Soulet L, Gautron J, Martelly I, Barritault D, (1996) Growth factors in skeletal muscle regeneration. Cytokine & growth factor reviews 7: 249-258.
46. Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, et al. (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117: 399-412.
47. Ponten EM, Stal PS, (2007) Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis. Journal of the neurological sciences 253: 25-33.
48. Scelsi R, Lotta S, Lommi G, Poggi P, Marchetti C, (1984) Hemiplegic atrophy. Morphological findings in the anterior tibial muscle of patients with cerebral vascular accidents. Acta neuropathologica 62: 324-331.
49. Neagoe C, Opitz CA, Makarenko I, Linke WA, (2003) Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness. Journal of muscle research and cell motility 24: 175-189.
50. Ducomps C, Mauriege P, Darche B, Combes S, Lebas F, et al. (2003) Effects of jump training on passive mechanical stress and stiffness in rabbit skeletal muscle: role of collagen. Acta physiologica Scandinavica 178: 215-224.
51. Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, et al. (2007) Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin. The FASEB journal: official publication of the Federation of American Societies for Experimental Biology 21: 1383-1392.
52. Kovanen V, (2002) Intramuscular extracellular matrix: complex environment of muscle cells. Exercise and sport sciences reviews 30: 20-25.
53. Dzienkowski RC, Smith KK, Dillow KA, Yucha CB, (1996) Cerebral palsy: a comprehensive review. The Nurse practitioner 21: 45-48, 51-44, 57-49; quiz 60-41.
54. Boonen KJ, Rosaria-Chak KY, Baaijens FP, van der Schaft DW, Post MJ, (2009) Essential environmental cues from the satellite cell niche: optimizing proliferation and differentiation. American journal of physiology Cell physiology 296: C1338-1345.
55. Gilbert PM, Havenstrite KL, Magnusson KE, Sacco A, Leonardi NA, et al. (2010) Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 329: 1078-1081.
56. Chen X, Li Y, (2009) Role of matrix metalloproteinases in skeletal muscle: migration, differentiation, regeneration and fibrosis. Cell adhesion & migration 3: 337-341.
57. Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, et al. (1997) Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol 39: 214-223.
58. Zhang B, Kirov S, Snoddy J, (2005) WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 33: W741-748.
59. Zhang B, Schmoyer D, Kirov S, Snoddy J, (2004) GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies. BMC Bioinformatics 5: 16.
60. Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, et al. (2007) Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2: 2366-2382.