The antidepressant drug fluoxetine inhibits persistent sodium currents and seizure-like events

Epilepsy Research

Volumn 101, Issue 1-2, 2012, Pages 174-181

  Igelström, Kajsa M ^a   Heyward, Philip M ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Antidepressant drug; Antiepileptic drug; Persistent sodium current; Selective serotonin reuptake inhibitor; Serotonin independent; Sodium channel inhibitor

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; FLUOXETINE; PHENYTOIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM ION; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ELECTROPHYSIOLOGY; EPILEPTIC DISCHARGE; MALE; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SEIZURE LIKE EVENT; SODIUM CURRENT;

ACTION POTENTIALS; ANIMALS; ANTICONVULSANTS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PROCESSES; FLUOXETINE; MALE; MICE; NEURONS; OLFACTORY BULB; SEIZURES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN;

EID: 84865087634     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2012.03.019     Document Type: Article

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