Moving toward a generalizable application of central thalamic deep brain stimulation for support of forebrain arousal regulation in the severely injured brain

Annals of the New York Academy of Sciences

Volumn 1265, Issue 1, 2012, Pages 56-68

  Schiff, Nicholas D ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Consciousness; Intralaminar thalamus; Medium spiny neuron; Mesocircuit; Microcircuit

Indexed keywords

AMANTADINE; LEVODOPA; ZOLPIDEM;

AROUSAL; ARTICLE; BRAIN; BRAIN DEPTH STIMULATION; BRAIN INJURY; CENTRAL THALAMIC DEEP BRAIN STIMULATION; COGNITION; CONSCIOUSNESS; CONSCIOUSNESS DISORDER; DISEASE SEVERITY; HUMAN;

EID: 84865082354     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06712.x     Document Type: Article

References (78)

1. McLardy, T., Ervin, F., Mark, V., et al 1968. Attempted inset-electrodes-arousal from traumatic coma: neuropathological findings. Trans. Am. Neurol. Assoc. 93: 25-30.
2. Hassler, R., G. Dalle Ore, G. Dieckmann, et al 1969. Behavioural and EEG arousal induced by stimulation of unspecific projection systems in a patient with post-traumatic apallic syndrome. Electroencephalogr. Clin. Neurophysiol. 27: 306-310.
3. Cohadon, F. et al 1985. Deep brain stimulation in cases of prolonged traumatic unconsciousness. In Neurostimulation: An Overview. Y. Lazorthes & A.R.M. Upton, Eds.Futura Publishers. Mt. Kisco, NY.
4. Tsubokawa, T. et al 1990. Deep-brain stimulation in a persistent vegetative state: follow-up results and criteria for selection of candidates. Brain Inj. 4: 315-27.
5. Hosobuchi, Y. & C. Yingling 1993. The treatment of prolonged coma with neurostimulation. In Electrical and Magnetic Stimulation of the Brain and Spinal Cord. O. Devinsky, A. Beric & M. Dogali, Eds: 247-252. Raven Press, New York
6. Deliac, P., E. Richer, J. Berthomieu, et al 1993. Electrophysiological evolution of post-traumatic persistent vegetative states under thalamic stimulation. Report on 25 observations. Neurochirurgie 39: 293-303.
7. Sturm, V., A. Kuhner, H.P. Schmitt, et al 1979. Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction. Acta Neurochirurgica 47: 235-244.
8. Yamamoto, T., Y. Katayama, K. Kobayashi, et al 2010. Deep brain stimulation for the treatment of vegetative state. Eur. J. Neurosci. 32: 1145-1151.
9. The Multi-Society Task Force on PVS. 1994. Medical aspects of the persistent vegetative state (1). N. Engl. J. Med. 30: 1499-1508.
10. Giacino, J.T., S. Ashwal, N. Childs, et al 2002. The minimally conscious state: definition and diagnostic criteria. Neurology 58: 349-353.
11. Yamamoto, T. & Y. Katayama 2005. Deep brain stimulation therapy for the vegetative state. Neuropsychol. Rehabil. 15: 406-413.
12. Lammi, M.H., V.H. Smith, R.L. Tate & C.M. Taylor 2005. The minimally conscious state and recovery potential: a follow-up study 2 to 5 years after traumatic brain injury. Arch. Phys. Med. Rehabil. 86: 746-754.
13. Giacino, J.T. & K. Kalmar 1997. The vegetative and minimally conscious states: a comparison of clinical features and functional outcome. J. Head Trauma Rehabil. 12: 36-51.
14. Giacino, J.T., J. Whyte, E. Bagiella, et al 2012. Placebo-controlled trial of amantadine for severe traumatic brain injury. N. Engl. J. Med. 366: 819-826.
15. Estraneo, A., P. Moretta, V. Loreto, et al 2010. Late recovery after traumatic, anoxic, or hemorrhagic long-lasting vegetative state. Neurology 75: 239-45. Epub 2010 Jun 16.
16. Luauté, J., D. Maucort-Boulch, L. Tell, et al 2010. Long-term outcomes of chronic minimally conscious and vegetative states. Neurology 75: 246-252.
17. Nakase-Richardson, R., J. Whyte, J.T. Giacino, et al 2012. Longitudinal outcome of patients with disordered consciousness in the NIDRR TBI Model Systems Programs. J. Neurotrauma 29: 59-65.
18. Fins, J.J., H.S. Mayberg, B. Nuttin, et al 2011. Misuse of the FDA's humanitarian device exemption in deep brain stimulation for obsessive-compulsive disorder. Health Aff. 30: 302-311.
19. Schiff, N.D. & J.J. Fins 2007. Deep brain stimulation and cognition: moving from animal to patient. Curr. Opin. Neurol. 20: 638-642.
20. Shah, S. & N.D. Schiff 2010. Central thalamic deep brain stimulation for cognitive neuromodulation: a review of proposed mechanisms and investigational studies. Eur. J. Neurosci. 32: 1135-1144.
21. Schiff, N.D., J.T. Giacino, K. Kalmar, et al 2007. Behavioural improvements with thalamic stimulation after severe traumatic brain injury. Nature 448: 600-603.
22. Dragunow, M. & H.A. Robertson 1988. Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brain. Brain Res. 455: 295-299.
23. Herrera, D.G. & H.A. Robertson 1996. Activation of c-fos in the brain. Prog. Neurobiol. 50: 83-107.
24. Giacino, J.T., A. Machado, J. Fins & N.D. Schiff 2012. Central thalamic deep brain stimulation to promote recovery from chronic post-traumatic minimally conscious state: challenges and opportunities. Neuromodulation. 2012 May 24. doi: 10.1111/j.1525-1403.2012.00458.x. Epub ahead of print.
25. Smith, A.C., S.A. Shah, A.E. Hudson, et al 2009. A Bayesian statistical analysis of behavioral facilitation associated with deep brain stimulation. J. Neurosci. Methods 183: 267-276.
26. Schiff, N.D. 2010. Recovery of consciousness after severe brain injury: the role of arousal regulation mechanisms and some speculation on the heart-brain interface. Cleve. Clin. J. Med. 77 (Suppl 3): S27-33.
27. Schiff, N.D. & J.P. Posner 2007. Another "Awakenings. Ann. Neurol. 62: 5-7.
28. Schiff, N.D. 2010. Recovery of consciousness after brain injury: a mesocircuit hypothesis. Trends Neurosci. 33: 1-9.
29. Brown, E.N., R. Lydic & N.D. Schiff General anesthesia, sleep and coma. N. Engl. J. Med. 363: 2638-2650.
30. Gold, L. & M. Lauritzen 2002. Neuronal deactivation explains decreased cerebellar blood flow in response to focal cerebral ischemia or suppressed neocortical function. Proc. Natl. Acad. Sci. U.S.A. 99: 7699-7704.
31. Maxwell, W.L., M.A. MacKinnon, D.H. Smith, et al 2006. Thalamic nuclei after human blunt head injury. J. Neuropathol. Exp. Neurol. 65: 478-488.
32. Mair, R.G., K.D. Onos & J.R. Hembrook 2011. Cognitive activation by central thalamic stimulation: the Yerkes-Dodson law revisited. Dose Response 9: 313-331.
33. Glenn, L.L. & M. Steriade 1982. Discharge rate and excitability of corticallyprojecting intralaminar thalamic neurons during waking and sleep states. J. Neurosci. 2: 1287-1404.
34. Steriade, M. & L.L. Glenn 1982. Neocortical and caudate projections of intralaminar thalamic neurons and their synaptic excitation from midbrain reticular core. J. Neurophysiol. 48: 352-371.
35. Parvizi, J. & A. Damasio 2001. Consciousness and the brainstem. Cognition 79: 135-160.
36. Schiff, N.D. 2008. Central thalamic contributions to arousal regulation and neurological disorders of consciousness. Ann. N.Y. Acad. Sci. 1129: 105-118.
37. Rigas, P. & M.A. Castro-Alamancos 2007. Thalamocortical Up states: differential effects of intrinsic and extrinsic cortical inputs on persistent activity. J. Neurosci. 27: 4261-4272.
38. Rudolph, M., J.G. Pelletier, D. Paré & A. Destexhe 2005. Characterization of synaptic conductances and integrative properties during electrically induced EEG-activated states in neocortical neurons in vivo. J. Neurophysiol. 94: 2805-2821.
39. Haider, B. & D.A. McCormick 2009. Rapid neocortical dynamics: cellular and network mechanisms. Neuron 62: 171-189.
40. Albin, R.L., A.B. Young & J.B. Penney 1989. The functional anatomy of basal ganglia disorders. Trends Neurosci. 12: 366-75.
41. DeLong, M.R. 1990. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13: 281-285.
42. Montgomery, E.B. Jr. 2007. Basal ganglia physiology and pathophysiology: a reappraisal. Parkinsonism Relat. Disord. 13: 455-65.
43. Goldman, M. 2009. Memory without feedback in a neural network. Neuron 61: 621-634.
44. Shah, S., J. Drover, N. Schiff & K. Purpura 2010. Distributed feed-forward network activity may underlie the contextual flexibility of neurons within the frontal cortex and central thalamus. Soci. Neurosci. Abs. #201.12.
45. Grillner, S., J. Hellgren, A. Ménard, et al. 2005. Mechanisms for selection of basic motor programs-roles for the striatum and pallidum. Trends Neurosci. 28: 364-370.
46. Deschenes, M., J. Bourassa & A. Parent 1996. Striatal and cortical projections of single neurons from the central lateral thalamic nucleus in the rat. Neuroscience 72: 679-687.
47. Deschênes, M., J. Bourassa, V.D. Doan & A. Parent 1996. A single-cell study of the axonal projections arising from the posterior intralaminar thalamic nuclei in the rat. Eur. J. Neurosci. 8: 329-343.
48. Haber, S.N., D. Boisson & C. Fischer 2003. The primate basal ganglia: parallel and integrative networks. J. Chem. Neuroanat. 26: 317-330.
49. Haber, S.N., K.S. Kim, P. Mailly & R. Calzavara 2006. Reward-related cortical inputs define a large striatal region in primates that interface with associative cortical connections, providing a substrate for incentive-based learning. J. Neurosci. 26: 8368-8376.
50. Goldberg, J.H. & M.S. Fee 2012. A cortical motor nucleus drives the basal ganglia-recipient thalamus in singing birds. Nat. Neurosci. 15: 620-627.
51. Morel, A. et al 2005. Divergence and convergence of thalamocortical projections to premotor and supplementary motor cortex: a multiple tracing study in the macaque monkey. Eur. J. Neurosci. 21: 1007-1029.
52. Barbas, H. & D.N. Pandya 1989. Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey. Comp. Neurol. 286: 353-375.
53. Lacey, C.J., J.P. Bolam & P.J. Magill 2007. Novel and distinct operational principles of intralaminar thalamic neurons and their striatal projections. J. Neurosci. 27: 4374-4384.
54. Jasper, H. 1960. Unspecific thalamo-cortical relations. In Handbook of Physiology, Vol. 2. J. Field, Ed. American Physiological Society. Washington, D.C.
55. Hamani, C., M. Diwan, S. Isabella, et al 2010. Effects of different stimulation parameters on the antidepressant-like response of medial prefrontal cortex deep brain stimulation in rats. Psychiatr. Res. 44: 683-687.
56. Poulet, J.F., L.M. Fernandez, S. Crochet & C.C. Petersen 2012. Thalamic control of cortical states. Nat. Neurosci. 15 370-372.
57. Fridman, E.A., B.Z. Krimchansky, M. Bonetto, et al 2010. Continuous subcutaneous apomorphine for severe disorders of consciousness after traumatic brain injury. Brain Inj. 24: 636-641.
58. Rieck, R.W., M.S. Ansari, W.O. Whetsell, Jr., et al. 2004. Distribution of dopamine D2-like receptors in the human thalamus: autoradiographic and PET studies. Neuropsychopharmacology 29: 362-372.
59. Mair, R.G. & J.R. Hembrook, 2008. Memory enhancement with event-related stimulation of the rostral intralaminar thalamic nuclei. J. Neurosci. 28: 14293-14300.
60. Brefel-Courbon C. et al 2007. Clinical and imaging evidence of zolpidem effect in hypoxic encephalopathy. Ann. Neurol. 62: 102-105.
61. Steriade, M. 2001. Neocortical neurons are flexible entities. Nat. Rev. Neurosci. 2: 121-134.
62. Steriade, M. et al 2001. Natural waking and sleep states: a view from inside neocortical neurons. J. Neurophysiol. 85: 1969-1985.
63. Montgomery, E.B. Jr. & J.T. Gale 2008. Mechanisms of action of deep brain stimulation(DBS). Neurosci. Biobehav. Rev. 32: 388-407.
64. Schiff, N.D. & K.P. Purpura 2002. Towards a neurophysiological basis for cognitive neuromodulation. Thalam. Relat. Syst. 2: 55-69.
65. Shah, S.A., J.L. Baker, J.W. Ryou, et al 2009. Modulation of arousal regulation with central thalamic deep brain stimulation. Conf. Proc. IEEE Eng. Med. Biol. Soc. 1: 3314-3317.
66. Purpura, K.P. & N.D. Schiff 1997. The thalamic intralaminar nuclei: a role in visual awareness. The Neuroscientist 3: 8-15.
67. Larkum, M.E., J.J. Zhu & B. Sakmann 1999. A new cellular mechanism for coupling inputs arriving at different cortical layers. Nature 398: 338-341.
68. Larkum, M.E. et al 2007. Dendritic spikes in apical dendrites of neocortical layer 2/3 pyramidal neurons. J. Neurosci. 27: 8999-9008.
69. Kuczewski, N. et al 2008. Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. J. Neurosci. 28: 7013-7023.
70. Shirvalkar, P., M. Seth, N.D. Schiff & D.G. Herrera 2006. Cognitive enhancement through central thalamic deep brain stimulation. Proc. Natl. Acad. Sci. 103: 17007-17012.
71. Schiff, N., D. Rodriguez-Moreno, A. Kamal, et al 2005. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 64: 514-523.
72. Ponce, F.A. & A.M. Lozano 2011. Deep brain stimulation state of the art and novel stimulation targets. Prog. Brain Res. 184: 311-324.
73. J.L. Baker, J.W. Ryou, X.F. Wei, et al 2011. Modulation of global beta oscillations within the frontal-striatal-central thalamic network during sustained attention. 2011 Society for Neuroscience Meeting. Abstract #197.26/WW21.
74. Voss, H.U. et al 2006. Possible axonal regrowth in late recovery from minimally conscious state. J. Clin. Invest. 116: 2005-2011.
75. Bredt, D.S. & R.A. Nicoll 2003. AMPA Receptor trafficking at excitatory synapses. Neuron 40: 361-379 2003.
76. Fins, J.J. 2003. Constructing an ethical stereotaxy for severe brain injury: balancing risks, benefits and access. Nat. Rev. Neurosci. 4: 323-327.
77. Wei, X.F., J.L. Baker, J.W. Ryou, et al. 2011. Butson computational analysis of volume of tissue activated during central thalamic deep brain stimulation in macaque monkey. 2011 Society for Neuroscience Meeting. Abstract # 197.13/WW8.
78. Williams, S.T., M.C. Conte, A.M. Goldfine, et al 2009. Zolpidem-induced behavioral facilitation in severe brain injury reveals common mechanism of dysfunction and recovery across etiologies. Society for Neuroscience Abstract: Program No. 541.6/R9. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience.