The effect of hepatic encephalopathy, hepatic failure, and portosystemic shunt on brain volume of cirrhotic patients: A voxel-based morphometry study

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Zhang, Long Jiang ^a   Qi, Rongfeng ^a   Zhong, Jianhui ^b   Xu, Qiang ^c   Zheng, Gang ^a   Lu, Guang Ming ^a  

^a NANJING UNIVERSITY   (China)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA;

ADULT; AMMONIA BLOOD LEVEL; ARTICLE; BRAIN REGION; BRAIN SIZE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GRAY MATTER; HEPATIC ENCEPHALOPATHY; HUMAN; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; NEUROANATOMY; NEUROPSYCHOLOGICAL TEST; PORTOSYSTEMIC ANASTOMOSIS; QUANTITATIVE ANALYSIS; THALAMUS; VOXEL BASED MORPHOMETRY; WHITE MATTER;

BRAIN; DISEASE PROGRESSION; FEMALE; HEPATIC ENCEPHALOPATHY; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; ORGAN SIZE; PORTASYSTEMIC SHUNT, TRANSJUGULAR INTRAHEPATIC; PROGNOSIS;

EID: 84865060521     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042824     Document Type: Article

References (31)

1. Córdoba J, (2011) New assessment of hepatic encephalopathy. J Hepatol 54: 1030-1040.
2. Guevara M, Baccaro ME, Gómez-Ansón B, Frisoni G, Testa C, et al. (2011) Cerebral magnetic resonance imaging reveals marked abnormalities of brain tissue density in patients with cirrhosis without overt hepatic encephalopathy. J Hepatol 55: 564-573.
3. Chen HJ, Zhu XQ, Shu H, Yang M, Zhang Y, et al. (2011) Structural and functional cerebral impairments in cirrhotic patients with a history of overt hepatic encephalopathy. Eur J Radiol. 2011 Nov 4. [Epub ahead of print].
4. Rovira A, Alonso J, Cordoba J, (2008) MR imaging findings in hepatic encephalopathy. AJNR Am J Neroradiol 29: 1612-1621.
5. Zhang LJ, Yang G, Yin J, Liu Y, Qi J, (2007) Neural mechanism of cognitive control impairment in patients with hepatic cirrhosis: a functional magnetic resonance imaging study. Acta Radiol 48: 577-587.
6. Zhang LJ, Yang G, Yin J, Liu Y, Qi J, (2007) Abnormal default-mode network activation in cirrhotic patients: a functional magnetic resonance imaging study. Acta Radiol 48: 781-787.
7. Zhang L, Qi R, Wu S, Zhong J, Zhong Y, et al. (2012) Brain default-mode network abnormalities in hepatic encephalopathy: A resting-state functional MRI study. Hum Brain Mapp 33: 1384-1392.
8. Hsu TW, Wu CW, Cheng YF, Chen HL, Lu CH, et al. (2012) Impaired small-world network efficiency and dynamic functional distribution in patients with cirrhosis. PLoS One 7: e35266.
9. Krieger S, Jauss M, Jansen O, Stiehl A, Sauer P, et al. (1997) MRI findings in chronic hepatic encephalopathy depend on portosystemic shunt: results of a controlled prospective clinical investigation. J Hepatol 27: 121-126.
10. Wu X, Ding W, Cao J, Han J, Huang Q, et al. (2010) Favorable clinical outcome using a covered stent following transjugular intrahepatic portosystemic shunt in patients with portal hypertension. J Hepatobiliary Pancreat Sci 17: 701-708.
11. Pugh R, Murray-lyon I, Dawson J, (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60: 646-649.
12. Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, et al. (2002) Hepatic encephalopathy- definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 35: 716-721.
13. Yoshikawa T, Mitchell DG, (2011) MR evaluation of portal hypertensive collateral shunting vessels for predicting outcome after transjugular intrahepatic portosystemic shunt. Magn Reson Med Sci 10: 21-27.
14. Bryce TJ, Yeh BM, Qayyum A, Pacharn P, Bass NM, et al. (2003) CT signs of hepatofugal portal venous flow in patients with cirrhosis.AJR Am J Roentgenol. 181: 1629-1633.
15. Brancatelli G, Federle MP, Pealer K, Geller DA, (2001) Portal venous thrombosis or sclerosis in liver transplantation candidates: preoperative CT findings and correlation with surgical procedure. Radiology 220: 321-328.
16. Zeneroli ML, Cioni G, Vezzelli C, Grandi S, Crisi G, et al. (1987) Prevalence of brain atrophy in liver cirrhosis patients with chronic persistent encephalopathy. Evaluation by computed tomography. J Hepatol 4: 283-292.
17. Tarter RE, Hays AL, Sandford SS, Van Thiel DH, (1986) Cerebral morphological abnormalities associated with non-alcoholic cirrhosis. Lancet 2: 893-895.
18. Zhang LJ, Lu GM, Yin JZ, Qi J, (2010) Metabolic changes of anterior cingulate cortex in patients with hepatic cirrhosis: A magnetic resonance spectroscopy study. Hepatol Res 40: 777-785.
19. Mechtcheriakov S, Schocke M, Kugener A, Graziadei IW, Mattedi M, et al. (2005) Chemical shift magnetic resonance spectroscopy of cingulate gray matter in patients with minimal hepatic encephalopathy. Neuroradiology 47: 27-34.
20. Weissenborn K, Ahl B, Fischer-Wasels D, van den Hoff J, Hecker H, et al. (2007) Correlations between magnetic resonance spectroscopy alterations and cerebral ammonia and glucose metabolism in cirrhotic patients with and without hepatic encephalopathy. Gut 56: 1736-1742.
21. Ross BD, Jacobson S, Villamil F, Korula J, Kreis R, et al. (1994) Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities. Radiology 193: 457-463.
22. Matsusue E, Kinoshita T, Eohama E, Ogawa T, (2005) Cerebral cortical and white matter lesionsin chronic hepatic encephalopathy:MR-pathologic correlations. AJNR Am J Neuroradiol 26: 347-351.
23. Buterworth RF, (2011) Hepatic encephalopathy: A central neuroinflammatory disorder? Hepatology 53: 1372-1376.
24. Rodrigo R, Cauli O, Gomez-Pinedo U, Agusti A, Hernandez-Rabaza V, et al. (2010) Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy. Gastroenterology 139: 675-684.
25. DeLong M, Wichmann T, (2009) Update on models of basal ganglia function and dysfunction. Parkinsonism Relat Disord 15: S237-S240.
26. Gupta RK, Yadav SK, Rangan M, Rathore RK, Thomas MA, et al. (2010) Serum proinflammatory cytokines correlate with diffusion tensor imaging derived metrics and (1)H-MR spectroscopy in patients with acute liver failure. Metab Brain Dis 25: 355-361.
27. Kerns JG, Cohen JD, MacDonald AW 3rd, Cho RY, Stenger VA, et al (2004) Anterior cingulate conflict monitoring and adjustments in control. Science 303: 1023-1026.
28. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, et al. (2005) The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A 102: 9673-9678.
29. Greicius MD, Srivastava G, Reiss AL, Menon V, (2004) Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 101: 4637-4642.
30. Mantini D, Perrucci MG, Del Gratta C, Romani GL, Corbetta M, (2007) Electrophysiological signatures of resting state networks in the human brain. Proc Natl Acad Sci USA 104: 13170-13175.
31. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, et al. (2001) A default mode of brain function. Proc Natl Acad Sci USA 98: 676-682.