Serum proinflammatory cytokines correlate with diffusion tensor imaging derived metrics and 1H-MR spectroscopy in patients with acute liver failure

Metabolic Brain Disease

Volumn 25, Issue 3, 2010, Pages 355-361

  Gupta, Rakesh Kumar ^a   Yadav, Santosh Kumar ^a   Rangan, Murali ^a   Rathore, Ram Kishore Singh ^b   Thomas, Michael Albert ^c   Prasad, Kashi Nath ^a   Pandey, Chandra Mohan ^a   Saraswat, Vivek Anand ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

1H MR spectroscopy; Acute liver failure; Diffusion tensor imaging; Hyperammonemia; Proinflammatory cytokines

Indexed keywords

AMMONIA; CYTOKINE; GLUTAMIC ACID; GLUTAMINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AMMONIA BLOOD LEVEL; ANISOTROPY; ARTICLE; BRAIN EDEMA; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FEMALE; HUMAN; HYPERAMMONEMIA; LIVER FAILURE; MALE; PROTEIN BLOOD LEVEL; PROTON NUCLEAR MAGNETIC RESONANCE;

ADOLESCENT; ADULT; BRAIN EDEMA; CYTOKINES; DIFFUSION TENSOR IMAGING; FEMALE; HEPATIC ENCEPHALOPATHY; HUMANS; INFLAMMATION MEDIATORS; LIVER FAILURE, ACUTE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 78149411178     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-010-9206-x     Document Type: Article

References (27)

1. CE Atterbury WC Maddrey HO Conn 1978 Neomycin-sorbitol and lactulose in the treatment of acute portal-systemic encephalopathy. A controlled, double-blind clinical trial Am J Dig Dis 23 398 406 10.1007/BF01072921 354373 1:STN:280:DyaE1c3jt1GqsQ%3D%3D
2. PJ Basser 1995 Inferring microstructural features and the physiological state of tissues from diffusion-weighted images NMR Biomed 8 333 344 10.1002/nbm.1940080707 8739270 1:STN:280:DyaK28zivV2mtQ%3D%3D
3. AT Blei 2004 Infection, inflammation and hepatic encephalopathy, synergism redefined J Hepatol 40 327 330 10.1016/j.jhep.2003.12.007 14739106 (Pubitemid 38115840)
4. SW Brusilow R Traystman 1986 Hepatic encephalopathy N Engl J Med 20 314 786 787
5. O Cauli R Rodrigo B Piedrafita J Boix V Felipo 2007 Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts Hepatology 46 514 519 10.1002/hep.21734 17659565 1:CAS:528:DC%2BD2sXhtVSisbzP (Pubitemid 47344787)
6. L Chavarria M Oria J Romero-Gimenez J Alonso S Lope-Piedrafita J Cordoba 2010 Diffusion tensor imaging supports the cytotoxic origin of brain edema in a rat model of acute liver failure Gastroenterology 138 1566 1573 10.1053/j.gastro.2009.10.003 19843475 1:CAS:528:DC%2BC3cXlt1Sisbk%3D
7. J Cordoba J Gottstein A Blei 1996 Glutamine, myoinositol, and organic osmolytes after portacaval anastomosis in the rat: implications for ammonia-induced brain edema Hepatology 27 919 923
8. A Duchini S Govindarajan M Santucci G Zampi FM Hofman 1996 Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells J Investig Med 44 474 482 8952229 1:STN:280:DyaK2s7gvF2qtg%3D%3D
9. KM Hasan DL Parker AL Alexander 2001 Comparison of gradient encoding schemes for diffusion-tensor MRI J Magn Reson Imaging 13 769 780 10.1002/jmri.1107 11329200 1:STN:280:DC%2BD3Mvitlemtw%3D%3D (Pubitemid 32381856)
10. R Jalan SW Olde Damink PC Hayes NE Deutz A Lee 2004 Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow J Hepatol 41 613 620 10.1016/j.jhep.2004.06.011 15464242 1:CAS:528:DC%2BD2cXotF2isLg%3D (Pubitemid 39297797)
11. AR Jayakumar MD Norenberg 2010 The Na-K-Cl Co-transporter in astrocyte swelling Metab Brain Dis 25 31 38 10.1007/s11011-010-9180-3 20336356 1:CAS:528:DC%2BC3cXktlShtLs%3D
12. RA Kale RK Gupta VA Saraswat KM Hasan R Trivedi AM Mishra P Ranjan CM Pandey PA Narayana 2006 Demonstration of interstitial cerebral edema with diffusion tensor MR imaging in type C hepatic encephalopathy Hepatology 43 698 706 10.1002/hep.21114 16557540
13. A Martinez-Hernandez KP Bell MD Norenberger 1977 Glutamine synthetase: glial localization in brain Science 195 1356 1385 10.1126/science.14400 14400 1:CAS:528:DyaE2sXhsFejsbg%3D
14. MD Norenberg 1987 The role of astrocytes in hepatic encephalopathy Neurochem Pathol 6 13 33 10.1007/BF02833599 3306480 1:STN:280: DyaL2szhs1Srtg%3D%3D
15. JP O'Beirne M Chouhan RD Hughes 2006 The role of infection and inflammation in the pathogenesis of hepatic encephalopathy and cerebral edema in acute liver failure Nat Clin Pract Gastroenterol Hepatol 3 118 119 10.1038/ncpgasthep0417 16511529
16. M Odeh E Sabo I Srugo A Oliven 2005 Relationship between tumor necrosis factor-alpha and ammonia in patients with hepatic encephalopathy due to chronic liver failure Ann Med 37 603 612 10.1080/07853890500317414 16338762 1:CAS:528:DC%2BD2MXht1ynsbjP (Pubitemid 41780148)
17. SW Provencher 2001 Automatic quantitation of localized in vivo 1H spectra with LC Model NMR Biomed 14 260 264 10.1002/nbm.698 11410943 1:CAS:528:DC%2BD3MXlt1GlsrY%3D (Pubitemid 32611437)
18. V Rai K Nath VA Saraswat A Purwar RKS Rathore RK Gupta 2008 Measurement of cytotoxic and interstitial components of cerebral edema in acute hepatic failure by diffusion tensor imaging J Magn Reson Imaging 28 334 341 10.1002/jmri.21438 18626948
19. N Rolando JIM Wade M Davalos J Wendon J Philpott-Howard R Williams 2000 The systemic inflammatory response syndrome in acute liver failure Hepatology 32 734 739 10.1053/jhep.2000.17687 11003617 1:STN:280:DC%2BD3cvpsFKnuw%3D%3D
20. S Saksena V Rai VA Saraswat RKS Rathore A Purwar M Kumar MA Thomas RK Gupta 2008 Cerebral diffusion tensor imaging and in vivo proton magnetic resonance spectroscopy in patients with fulminant hepatic failure J Gastroenterol Hepatol 23 e111 e119 10.1111/j.1440-1746.2007.05158.x 17924951 1:CAS:528:DC%2BD1cXhsVaitr7J (Pubitemid 352019431)
21. DL Shawcross G Wright SWM Olde Damink R Jalan 2007 Role of ammonia and inflammation in minimal hepatic encephalopathy Metab Brain Dis 22 125 138 10.1007/s11011-006-9042-1 17260161 1:CAS:528:DC%2BD2sXisVejtr4%3D (Pubitemid 46354829)
22. BN Tandon J Bernauau J O'Grady SD Gupta RE Krisch YF Liaw K Okuda SK Acharya 1999 Recommendations of the International Association for the Study of the Liver Subcommittee on nomenclature of acute and subacute liver failure J Gastroenterol Hepatol 14 403 404 10.1046/j.1440-1746.1999.01905.x 10355501 1:STN:280:DyaK1M3otFKgsA%3D%3D (Pubitemid 29256172)
23. J Vaquero RJ Fontana AM Larson NM Bass TJ Davern AO Shakil S Han ME Harrison TR Stravitz S Munoz R Brown WM Lee AT Blei 2005 Complications and use of intracranial pressure monitoring in patients with acute liver failure and severe encephalopathy Liver Transplant 11 1581 1589 10.1002/lt.20625 (Pubitemid 43072637)
24. A Verma VA Saraswat RY Krishna K Nath MA Thomas RK Gupta 2008 Role of 1H-MR spectroscopy in the differentiation of acute on chronic liver failure from acute liver failure Liver Int 28 1095 1103 10.1111/j.1478-3231.2007.01648.x 18266634 1:CAS:528:DC%2BD1cXhtFWmsL%2FK
25. AJ Ware AN D'Agostino B Combes 1971 Cerebral edema: a major complication of massive hepatic necrosis Gastroenterology 61 877 884 5125688 1:STN:280:DyaE38%2Fls1ejsg%3D%3D
26. CF Westin SE Maier H Mamata A Nabavi FA Jolesz R Kikinis 2002 Processing and visualization for diffusion tensor MRI Med Image Anal 6 93 108 10.1016/S1361-8415(02)00053-1 12044998 (Pubitemid 35282820)
27. G Wright NA Davies DL Shawcross SJ Hodges C Zwingmann HF Brooks AR Mani D Harry V Stadlbauer Z Zou R Williams C Davies KP Moore R Jalan 2007 Endotoxemia produces coma and brain swelling in bile duct ligated rats Hepatology 45 1517 1526 10.1002/hep.21599 17523148 1:CAS:528:DC%2BD2sXnvFalu7o%3D (Pubitemid 46918336)