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Volumn 67, Issue 9, 2012, Pages 1106-1110

CX3CL1 in allergic diseases: Not just a chemotactic molecule

(1)  Julia, V a  

a CNRS   (France)

Author keywords

allergy; asthma; CX3CL1; CX3CR1

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CX3CR1; FRACTALKINE; LEUKOTRIENE; PROSTAGLANDIN;

EID: 84865024390     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2012.02870.x     Document Type: Review
Times cited : (29)

References (53)
  • 1
    • 0037561089 scopus 로고    scopus 로고
    • Are asthma and allergies in children and adolescents increasing? Results from ISAAC phase i and phase III surveys in Munster, Germany
    • et al.
    • Maziak W, Behrens T, Brasky TM, Duhme H, Rzehak P, Weiland SK, et al. Are asthma and allergies in children and adolescents increasing? Results from ISAAC phase I and phase III surveys in Munster, Germany. Allergy 2003; 58: 572-579.
    • (2003) Allergy , vol.58 , pp. 572-579
    • Maziak, W.1    Behrens, T.2    Brasky, T.M.3    Duhme, H.4    Rzehak, P.5    Weiland, S.K.6
  • 2
    • 33644836000 scopus 로고    scopus 로고
    • Atopic dermatitis, extrinsic atopic dermatitis and the hygiene hypothesis: Results from a cross-sectional study
    • Zutavern A, Hirsch T, Leupold W, Weiland S, Keil U, von Mutius E,. Atopic dermatitis, extrinsic atopic dermatitis and the hygiene hypothesis: results from a cross-sectional study. Clin Exp Allergy 2005; 35: 1301-1308.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1301-1308
    • Zutavern, A.1    Hirsch, T.2    Leupold, W.3    Weiland, S.4    Keil, U.5    Von Mutius, E.6
  • 3
    • 23844546540 scopus 로고    scopus 로고
    • Much atopy about the skin: Genome-wide molecular analysis of atopic eczema
    • Saito H,. Much atopy about the skin: genome-wide molecular analysis of atopic eczema. Int Arch Allergy Immunol 2005; 137: 319-325.
    • (2005) Int Arch Allergy Immunol , vol.137 , pp. 319-325
    • Saito, H.1
  • 4
    • 77955228542 scopus 로고    scopus 로고
    • From atopic dermatitis to asthma: The atopic march
    • quiz 7-9, 17.
    • Spergel JM,. From atopic dermatitis to asthma: the atopic march. Ann Allergy Asthma Immunol 2010; 105: 99-106; quiz 7-9, 17.
    • (2010) Ann Allergy Asthma Immunol , vol.105 , pp. 99-106
    • Spergel, J.M.1
  • 5
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M,. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999; 17: 255-281.
    • (1999) Annu Rev Immunol , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 6
    • 2342590065 scopus 로고    scopus 로고
    • The global burden of asthma: Executive summary of the GINA Dissemination Committee report
    • Masoli M, Fabian D, Holt S, Beasley R,. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004; 59: 469-478.
    • (2004) Allergy , vol.59 , pp. 469-478
    • Masoli, M.1    Fabian, D.2    Holt, S.3    Beasley, R.4
  • 7
    • 0031036347 scopus 로고    scopus 로고
    • A new class of membrane-bound chemokine with a CX3C motif
    • et al.
    • Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, et al. A new class of membrane-bound chemokine with a CX3C motif. Nature 1997; 385: 640-644.
    • (1997) Nature , vol.385 , pp. 640-644
    • Bazan, J.F.1    Bacon, K.B.2    Hardiman, G.3    Wang, W.4    Soo, K.5    Rossi, D.6
  • 8
    • 35348814982 scopus 로고    scopus 로고
    • IL-13-induced proliferation of airway epithelial cells: Mediation by intracellular growth factor mobilization and ADAM17
    • Booth BW, Sandifer T, Martin EL, Martin LD,. IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17. Respir Res 2007; 8: 51.
    • (2007) Respir Res , vol.8 , pp. 51
    • Booth, B.W.1    Sandifer, T.2    Martin, E.L.3    Martin, L.D.4
  • 9
    • 57749119534 scopus 로고    scopus 로고
    • Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells
    • et al.
    • Hartl D, He CH, Koller B, Da Silva CA, Homer R, Lee CG, et al. Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. J Biol Chem 2008; 283: 33472-33482.
    • (2008) J Biol Chem , vol.283 , pp. 33472-33482
    • Hartl, D.1    He, C.H.2    Koller, B.3    Da Silva, C.A.4    Homer, R.5    Lee, C.G.6
  • 12
    • 0035104518 scopus 로고    scopus 로고
    • The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo
    • et al.
    • Lucas AD, Chadwick N, Warren BF, Jewell DP, Gordon S, Powrie F, et al. The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo. Am J Pathol 2001; 158: 855-866.
    • (2001) Am J Pathol , vol.158 , pp. 855-866
    • Lucas, A.D.1    Chadwick, N.2    Warren, B.F.3    Jewell, D.P.4    Gordon, S.5    Powrie, F.6
  • 14
    • 2342516024 scopus 로고    scopus 로고
    • Expression of fractalkine and its receptor, CX3CR1, in atopic dermatitis: Possible contribution to skin inflammation
    • Echigo T, Hasegawa M, Shimada Y, Takehara K, Sato S,. Expression of fractalkine and its receptor, CX3CR1, in atopic dermatitis: possible contribution to skin inflammation. J Allergy Clin Immunol 2004; 113: 940-948.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 940-948
    • Echigo, T.1    Hasegawa, M.2    Shimada, Y.3    Takehara, K.4    Sato, S.5
  • 15
    • 31144477001 scopus 로고    scopus 로고
    • Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma
    • et al.
    • El-Shazly A, Berger P, Girodet PO, Ousova O, Fayon M, Vernejoux JM, et al. Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma. J Immunol 2006; 176: 1860-1868.
    • (2006) J Immunol , vol.176 , pp. 1860-1868
    • El-Shazly, A.1    Berger, P.2    Girodet, P.O.3    Ousova, O.4    Fayon, M.5    Vernejoux, J.M.6
  • 16
    • 82155183271 scopus 로고    scopus 로고
    • In vivo structure/function and expression analysis of the CX3C chemokine fractalkine
    • et al.
    • Kim KW, Vallon-Eberhard A, Zigmond E, Farache J, Shezen E, Shakhar G, et al. In vivo structure/function and expression analysis of the CX3C chemokine fractalkine. Blood 2011; 118: e156-e167.
    • (2011) Blood , vol.118
    • Kim, K.W.1    Vallon-Eberhard, A.2    Zigmond, E.3    Farache, J.4    Shezen, E.5    Shakhar, G.6
  • 17
    • 13144279282 scopus 로고    scopus 로고
    • Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    • et al.
    • Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, et al. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci USA 1998; 95: 10896-10901.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10896-10901
    • Harrison, J.K.1    Jiang, Y.2    Chen, S.3    Xia, Y.4    MacIejewski, D.5    McNamara, R.K.6
  • 18
    • 0030723388 scopus 로고    scopus 로고
    • Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion
    • et al.
    • Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, et al. Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 1997; 91: 521-530.
    • (1997) Cell , vol.91 , pp. 521-530
    • Imai, T.1    Hieshima, K.2    Haskell, C.3    Baba, M.4    Nagira, M.5    Nishimura, M.6
  • 19
    • 0035336402 scopus 로고    scopus 로고
    • Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire
    • et al.
    • Campbell JJ, Qin S, Unutmaz D, Soler D, Murphy KE, Hodge MR, et al. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol 2001; 166: 6477-6482.
    • (2001) J Immunol , vol.166 , pp. 6477-6482
    • Campbell, J.J.1    Qin, S.2    Unutmaz, D.3    Soler, D.4    Murphy, K.E.5    Hodge, M.R.6
  • 20
    • 0037097775 scopus 로고    scopus 로고
    • Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression
    • et al.
    • Nishimura M, Umehara H, Nakayama T, Yoneda O, Hieshima K, Kakizaki M, et al. Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression. J Immunol 2002; 168: 6173-6180.
    • (2002) J Immunol , vol.168 , pp. 6173-6180
    • Nishimura, M.1    Umehara, H.2    Nakayama, T.3    Yoneda, O.4    Hieshima, K.5    Kakizaki, M.6
  • 21
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • et al.
    • Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 2000; 20: 4106-4114.
    • (2000) Mol Cell Biol , vol.20 , pp. 4106-4114
    • Jung, S.1    Aliberti, J.2    Graemmel, P.3    Sunshine, M.J.4    Kreutzberg, G.W.5    Sher, A.6
  • 22
    • 77957085835 scopus 로고    scopus 로고
    • CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells
    • et al.
    • Bar-On L, Birnberg T, Lewis KL, Edelson BT, Bruder D, Hildner K, et al. CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells. Proc Natl Acad Sci USA 2010; 107: 14745-14750.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14745-14750
    • Bar-On, L.1    Birnberg, T.2    Lewis, K.L.3    Edelson, B.T.4    Bruder, D.5    Hildner, K.6
  • 24
    • 0035725605 scopus 로고    scopus 로고
    • Cellular localization of fractalkine at sites of inflammation: Antigen-presenting cells in psoriasis express high levels of fractalkine
    • Raychaudhuri SP, Jiang WY, Farber EM,. Cellular localization of fractalkine at sites of inflammation: antigen-presenting cells in psoriasis express high levels of fractalkine. Br J Dermatol 2001; 144: 1105-1113.
    • (2001) Br J Dermatol , vol.144 , pp. 1105-1113
    • Raychaudhuri, S.P.1    Jiang, W.Y.2    Farber, E.M.3
  • 25
    • 30944461598 scopus 로고    scopus 로고
    • CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation
    • Ottaviani C, Nasorri F, Bedini C, de Pita O, Girolomoni G, Cavani A,. CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation. Eur J Immunol 2006; 36: 118-128.
    • (2006) Eur J Immunol , vol.36 , pp. 118-128
    • Ottaviani, C.1    Nasorri, F.2    Bedini, C.3    De Pita, O.4    Girolomoni, G.5    Cavani, A.6
  • 26
    • 53149090155 scopus 로고    scopus 로고
    • CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema
    • et al.
    • McComb JG, Ranganathan M, Liu XH, Pilewski JM, Ray P, Watkins SC, et al. CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema. Am J Pathol 2008; 173: 949-961.
    • (2008) Am J Pathol , vol.173 , pp. 949-961
    • McComb, J.G.1    Ranganathan, M.2    Liu, X.H.3    Pilewski, J.M.4    Ray, P.5    Watkins, S.C.6
  • 27
    • 6944222804 scopus 로고    scopus 로고
    • Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease
    • et al.
    • Ning W, Li CJ, Kaminski N, Feghali-Bostwick CA, Alber SM, Di YP, et al. Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci USA 2004; 101: 14895-14900.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14895-14900
    • Ning, W.1    Li, C.J.2    Kaminski, N.3    Feghali-Bostwick, C.A.4    Alber, S.M.5    Di, Y.P.6
  • 30
    • 30344472950 scopus 로고    scopus 로고
    • Polymorphism of the fractalkine receptor CX3CR1 and systemic sclerosis-associated pulmonary arterial hypertension
    • et al.
    • Marasini B, Cossutta R, Selmi C, Pozzi MR, Gardinali M, Massarotti M, et al. Polymorphism of the fractalkine receptor CX3CR1 and systemic sclerosis-associated pulmonary arterial hypertension. Clin Dev Immunol 2005; 12: 275-279.
    • (2005) Clin Dev Immunol , vol.12 , pp. 275-279
    • Marasini, B.1    Cossutta, R.2    Selmi, C.3    Pozzi, M.R.4    Gardinali, M.5    Massarotti, M.6
  • 31
    • 52949138321 scopus 로고    scopus 로고
    • Fractalkine in rheumatoid arthritis: A review to date
    • Murphy G, Caplice N, Molloy M,. Fractalkine in rheumatoid arthritis: a review to date. Rheumatology (Oxford) 2008; 47: 1446-1451.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 1446-1451
    • Murphy, G.1    Caplice, N.2    Molloy, M.3
  • 32
    • 0037465557 scopus 로고    scopus 로고
    • Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein e double knockout mice
    • et al.
    • Combadiere C, Potteaux S, Gao JL, Esposito B, Casanova S, Lee EJ, et al. Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 2003; 107: 1009-1016.
    • (2003) Circulation , vol.107 , pp. 1009-1016
    • Combadiere, C.1    Potteaux, S.2    Gao, J.L.3    Esposito, B.4    Casanova, S.5    Lee, E.J.6
  • 33
    • 85047687223 scopus 로고    scopus 로고
    • Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis
    • Lesnik P, Haskell CA, Charo IF,. Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. J Clin Invest 2003; 111: 333-340.
    • (2003) J Clin Invest , vol.111 , pp. 333-340
    • Lesnik, P.1    Haskell, C.A.2    Charo, I.F.3
  • 36
    • 78149360636 scopus 로고    scopus 로고
    • CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung
    • et al.
    • Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, et al. CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung. Nat Med 2010; 16: 1305-1312.
    • (2010) Nat Med , vol.16 , pp. 1305-1312
    • Mionnet, C.1    Buatois, V.2    Kanda, A.3    Milcent, V.4    Fleury, S.5    Lair, D.6
  • 37
    • 0037115760 scopus 로고    scopus 로고
    • Cloning and functional characterization of the human fractalkine receptor promoter regions
    • Garin A, Pellet P, Deterre P, Debre P, Combadiere C,. Cloning and functional characterization of the human fractalkine receptor promoter regions. Biochem J 2002; 368: 753-760.
    • (2002) Biochem J , vol.368 , pp. 753-760
    • Garin, A.1    Pellet, P.2    Deterre, P.3    Debre, P.4    Combadiere, C.5
  • 38
    • 77949399168 scopus 로고    scopus 로고
    • Interleukin-10 and interferon-gamma modulate surface expression of fractalkine-receptor (CX(3)CR1) via PI3K in monocytes
    • et al.
    • Ramos MV, Fernandez GC, Brando RJ, Panek CA, Bentancor LV, Landoni VI, et al. Interleukin-10 and interferon-gamma modulate surface expression of fractalkine-receptor (CX(3)CR1) via PI3K in monocytes. Immunology 2010; 129: 600-609.
    • (2010) Immunology , vol.129 , pp. 600-609
    • Ramos, M.V.1    Fernandez, G.C.2    Brando, R.J.3    Panek, C.A.4    Bentancor, L.V.5    Landoni, V.I.6
  • 39
    • 0242579375 scopus 로고    scopus 로고
    • IL-15 and IL-2 oppositely regulate expression of the chemokine receptor CX3CR1
    • Barlic J, Sechler JM, Murphy PM,. IL-15 and IL-2 oppositely regulate expression of the chemokine receptor CX3CR1. Blood 2003; 102: 3494-3503.
    • (2003) Blood , vol.102 , pp. 3494-3503
    • Barlic, J.1    Sechler, J.M.2    Murphy, P.M.3
  • 40
    • 10344225071 scopus 로고    scopus 로고
    • IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells
    • Sechler JM, Barlic J, Grivel JC, Murphy PM,. IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells. Cell Immunol 2004; 230: 99-108.
    • (2004) Cell Immunol , vol.230 , pp. 99-108
    • Sechler, J.M.1    Barlic, J.2    Grivel, J.C.3    Murphy, P.M.4
  • 41
    • 0034608742 scopus 로고    scopus 로고
    • Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival
    • Meucci O, Fatatis A, Simen AA, Miller RJ,. Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival. Proc Natl Acad Sci USA 2000; 97: 8075-8080.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8075-8080
    • Meucci, O.1    Fatatis, A.2    Simen, A.A.3    Miller, R.J.4
  • 42
    • 0034141496 scopus 로고    scopus 로고
    • Neuronal fractalkine expression in HIV-1 encephalitis: Roles for macrophage recruitment and neuroprotection in the central nervous system
    • et al.
    • Tong N, Perry SW, Zhang Q, James HJ, Guo H, Brooks A, et al. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. J Immunol 2000; 164: 1333-1339.
    • (2000) J Immunol , vol.164 , pp. 1333-1339
    • Tong, N.1    Perry, S.W.2    Zhang, Q.3    James, H.J.4    Guo, H.5    Brooks, A.6
  • 44
    • 0037821637 scopus 로고    scopus 로고
    • Production and neuroprotective functions of fractalkine in the central nervous system
    • Mizuno T, Kawanokuchi J, Numata K, Suzumura A,. Production and neuroprotective functions of fractalkine in the central nervous system. Brain Res 2003; 979: 65-70.
    • (2003) Brain Res , vol.979 , pp. 65-70
    • Mizuno, T.1    Kawanokuchi, J.2    Numata, K.3    Suzumura, A.4
  • 45
    • 59649092443 scopus 로고    scopus 로고
    • CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
    • et al.
    • Landsman L, Bar-On L, Zernecke A, Kim KW, Krauthgamer R, Shagdarsuren E, et al. CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 2009; 113: 963-972.
    • (2009) Blood , vol.113 , pp. 963-972
    • Landsman, L.1    Bar-On, L.2    Zernecke, A.3    Kim, K.W.4    Krauthgamer, R.5    Shagdarsuren, E.6
  • 47
    • 0033179228 scopus 로고    scopus 로고
    • Characterization of fractalkine in rat brain cells: Migratory and activation signals for CX3CR-1-expressing microglia
    • Maciejewski-Lenoir D, Chen S, Feng L, Maki R, Bacon KB,. Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia. J Immunol 1999; 163: 1628-1635.
    • (1999) J Immunol , vol.163 , pp. 1628-1635
    • MacIejewski-Lenoir, D.1    Chen, S.2    Feng, L.3    Maki, R.4    Bacon, K.B.5
  • 48
    • 0035943612 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-dependent extracellular calcium influx is essential for CX(3)CR1-mediated activation of the mitogen-activated protein kinase cascade
    • Kansra V, Groves C, Gutierrez-Ramos JC, Polakiewicz RD,. Phosphatidylinositol 3-kinase-dependent extracellular calcium influx is essential for CX(3)CR1-mediated activation of the mitogen-activated protein kinase cascade. J Biol Chem 2001; 276: 31831-31838.
    • (2001) J Biol Chem , vol.276 , pp. 31831-31838
    • Kansra, V.1    Groves, C.2    Gutierrez-Ramos, J.C.3    Polakiewicz, R.D.4
  • 49
    • 0035313378 scopus 로고    scopus 로고
    • Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion
    • et al.
    • Cambien B, Pomeranz M, Schmid-Antomarchi H, Millet MA, Breittmayer V, Rossi B, et al. Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion. Blood 2001; 97: 2031-2037.
    • (2001) Blood , vol.97 , pp. 2031-2037
    • Cambien, B.1    Pomeranz, M.2    Schmid-Antomarchi, H.3    Millet, M.A.4    Breittmayer, V.5    Rossi, B.6
  • 50
    • 29244478871 scopus 로고    scopus 로고
    • Proline 326 in the C terminus of murine CX3CR1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of Akt and extracellular signal-regulated kinase in Chinese hamster ovary cells
    • Davis CN, Harrison JK,. Proline 326 in the C terminus of murine CX3CR1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of Akt and extracellular signal-regulated kinase in Chinese hamster ovary cells. J Pharmacol Exp Ther 2006; 316: 356-363.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 356-363
    • Davis, C.N.1    Harrison, J.K.2
  • 51
    • 0032583595 scopus 로고    scopus 로고
    • Gene cloning, RNA distribution, and functional expression of mCX3CR1, a mouse chemotactic receptor for the CX3C chemokine fractalkine
    • Combadiere C, Gao J, Tiffany HL, Murphy PM,. Gene cloning, RNA distribution, and functional expression of mCX3CR1, a mouse chemotactic receptor for the CX3C chemokine fractalkine. Biochem Biophys Res Commun 1998; 253: 728-732.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 728-732
    • Combadiere, C.1    Gao, J.2    Tiffany, H.L.3    Murphy, P.M.4
  • 52
    • 34547699013 scopus 로고    scopus 로고
    • Severe asthma refractory to treatment: Concepts and realities
    • Lopez Vina A,. Severe asthma refractory to treatment: concepts and realities. Arch Bronconeumol 2006; 42: 20-25.
    • (2006) Arch Bronconeumol , vol.42 , pp. 20-25
    • Lopez Vina, A.1
  • 53
    • 36849086388 scopus 로고    scopus 로고
    • The demise of anti IL-5 for asthma, or not
    • O'Byrne PM,. The demise of anti IL-5 for asthma, or not. Am J Respir Crit Care Med 2007; 176: 1059-1060.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1059-1060
    • O'Byrne, P.M.1


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