Comparative effect of lidocaine, bupivacaine and RAC 109 on myocardial conduction and contractility in the rabbit

European Journal of Pharmacology

Volumn 691, Issue 1-3, 2012, Pages 110-117

  Kariya, Nobutaka ^a   Cosson, Claudine ^b   Mazoit, Jean Xavier ^a  

^a Universite Paris Sud   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

Bupivacaine; Cardiotoxicity; Contractility; Enantioselectivity

Indexed keywords

1' [3 (DIETHYLAMINO)PROPYL] 3,4 DIHYDROSPIRO[NAPHTHALENE 1(2H),3' PYRROLIDINE] 2',5' DIONE; BUPIVACAINE; LIDOCAINE; RYANODINE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL ISOLATION; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART PERFUSION; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE PRESSURE; HYDROPHOBICITY; IONIZATION; ISOLATED HEART; MYOCARDIAL DISEASE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; QRS COMPLEX; RABBIT; STEREOCHEMISTRY; VELOCITY;

ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; HEART CONDUCTION SYSTEM; LIDOCAINE; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NAPHTHALENES; PYRROLIDINONES; RABBITS; RYANODINE; SARCOPLASMIC RETICULUM;

EID: 84865008806     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.034     Document Type: Article

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