-
1
-
-
77958097499
-
Standard therapy for glioblastoma-A review of where we are
-
10.2176/nmc.50.713
-
R Nishikawa 2010 Standard therapy for glioblastoma-a review of where we are Neurol Med Chir (Tokyo) 50 9 713 719 10.2176/nmc.50.713
-
(2010)
Neurol Med Chir (Tokyo)
, vol.50
, Issue.9
, pp. 713-719
-
-
Nishikawa, R.1
-
2
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
19269895 10.1016/S1470-2045(09)70025-7 1:CAS:528:DC%2BD1MXlsVKhs74%3D
-
R Stupp ME Hegi, et al. 2009 Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial Lancet Oncol 10 5 459 466 19269895 10.1016/S1470-2045(09)70025-7 1:CAS:528: DC%2BD1MXlsVKhs74%3D
-
(2009)
Lancet Oncol
, vol.10
, Issue.5
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
-
3
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
15758009 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D
-
R Stupp WP Mason, et al. 2005 Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 10 987 996 15758009 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
-
4
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
12118245 1:CAS:528:DC%2BD38Xls12msbw%3D
-
S Fulda W Wick, et al. 2002 Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo Nat Med 8 8 808 815 12118245 1:CAS:528:DC%2BD38Xls12msbw%3D
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
-
5
-
-
34249085552
-
Proteasomes: Machines for all reasons
-
17512401 10.1016/j.cell.2007.05.007 1:CAS:528:DC%2BD2sXmtFGqurc%3D
-
GN Demartino TG Gillette 2007 Proteasomes: machines for all reasons Cell 129 4 659 662 17512401 10.1016/j.cell.2007.05.007 1:CAS:528:DC%2BD2sXmtFGqurc%3D
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 659-662
-
-
Demartino, G.N.1
Gillette, T.G.2
-
6
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
11960320 10.1038/sj.leu.2402417 1:CAS:528:DC%2BD38XjvFGnur8%3D
-
JB Almond GM Cohen 2002 The proteasome: a novel target for cancer chemotherapy Leukemia 16 4 433 443 11960320 10.1038/sj.leu.2402417 1:CAS:528:DC%2BD38XjvFGnur8%3D
-
(2002)
Leukemia
, vol.16
, Issue.4
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
7
-
-
0036855056
-
Proteasome inhibitors as new anticancer drugs
-
12409653 10.1097/00001622-200211000-00007 1:CAS:528:DC%2BD38XosFegtLs%3D
-
J Adams 2002 Proteasome inhibitors as new anticancer drugs Curr Opin Oncol 14 6 628 634 12409653 10.1097/00001622-200211000-00007 1:CAS:528:DC%2BD38XosFegtLs%3D
-
(2002)
Curr Opin Oncol
, vol.14
, Issue.6
, pp. 628-634
-
-
Adams, J.1
-
8
-
-
58149295169
-
Targeting the ubiquitin-proteasome system for cancer therapy
-
19037995 10.1111/j.1349-7006.2008.01013.x 1:CAS:528:DC%2BD1MXhtlGgurk%3D
-
Y Yang J Kitagaki, et al. 2009 Targeting the ubiquitin-proteasome system for cancer therapy Cancer Sci 100 1 24 28 19037995 10.1111/j.1349-7006.2008. 01013.x 1:CAS:528:DC%2BD1MXhtlGgurk%3D
-
(2009)
Cancer Sci
, vol.100
, Issue.1
, pp. 24-28
-
-
Yang, Y.1
Kitagaki, J.2
-
9
-
-
0036680037
-
Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer
-
12133726 10.1016/S1367-5931(02)00343-5 1:CAS:528:DC%2BD38XlsVyjur0%3D
-
J Adams 2002 Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer Curr Opin Chem Biol 6 4 493 500 12133726 10.1016/S1367-5931(02)00343-5 1:CAS:528:DC%2BD38XlsVyjur0%3D
-
(2002)
Curr Opin Chem Biol
, vol.6
, Issue.4
, pp. 493-500
-
-
Adams, J.1
-
10
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
10363983 1:CAS:528:DyaK1MXjs1ymsbY%3D
-
J Adams VJ Palombella, et al. 1999 Proteasome inhibitors: a novel class of potent and effective antitumor agents Cancer Res 59 11 2615 2622 10363983 1:CAS:528:DyaK1MXjs1ymsbY%3D
-
(1999)
Cancer Res
, vol.59
, Issue.11
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
-
11
-
-
0037342895
-
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines
-
12631620 1:CAS:528:DC%2BD3sXhvFKitbs%3D
-
YH Ling L Liebes, et al. 2003 Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines Clin Cancer Res 9 3 1145 1154 12631620 1:CAS:528: DC%2BD3sXhvFKitbs%3D
-
(2003)
Clin Cancer Res
, vol.9
, Issue.3
, pp. 1145-1154
-
-
Ling, Y.H.1
Liebes, L.2
-
12
-
-
33744959426
-
PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells
-
16446371 10.1074/jbc.M508533200 1:CAS:528:DC%2BD28Xjslens7s%3D
-
BH Yeung DC Huang, et al. 2006 PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells J Biol Chem 281 17 11923 11932 16446371 10.1074/jbc.M508533200 1:CAS:528:DC%2BD28Xjslens7s%3D
-
(2006)
J Biol Chem
, vol.281
, Issue.17
, pp. 11923-11932
-
-
Yeung, B.H.1
Huang, D.C.2
-
13
-
-
0012433771
-
Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts
-
12516957 1:CAS:528:DC%2BD3sXmtFamuw%3D%3D
-
ST Nawrocki CJ Bruns, et al. 2002 Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts Mol Cancer Ther 1 14 1243 1253 12516957 1:CAS:528: DC%2BD3sXmtFamuw%3D%3D
-
(2002)
Mol Cancer Ther
, vol.1
, Issue.14
, pp. 1243-1253
-
-
Nawrocki, S.T.1
Bruns, C.J.2
-
14
-
-
13244262655
-
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM)
-
15531918 10.1038/sj.onc.1208225 1:CAS:528:DC%2BD2MXnsFSgtQ%3D%3D
-
D Yin H Zhou, et al. 2005 Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM) Oncogene 24 3 344 354 15531918 10.1038/sj.onc.1208225 1:CAS:528:DC%2BD2MXnsFSgtQ%3D%3D
-
(2005)
Oncogene
, vol.24
, Issue.3
, pp. 344-354
-
-
Yin, D.1
Zhou, H.2
-
15
-
-
3042577683
-
Approval summary for bortezomib for injection in the treatment of multiple myeloma
-
15217925 10.1158/1078-0432.CCR-03-0781 1:CAS:528:DC%2BD2cXltFWmtLk%3D
-
PF Bross R Kane, et al. 2004 Approval summary for bortezomib for injection in the treatment of multiple myeloma Clin Cancer Res 10 12 Pt 1 3954 3964 15217925 10.1158/1078-0432.CCR-03-0781 1:CAS:528:DC%2BD2cXltFWmtLk%3D
-
(2004)
Clin Cancer Res
, vol.10
, Issue.12 PART 1
, pp. 3954-3964
-
-
Bross, P.F.1
Kane, R.2
-
16
-
-
79952194923
-
Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma
-
20213332 10.1007/s11060-010-0143-7 1:CAS:528:DC%2BC3cXht1Krsb3E
-
S Phuphanich JG Supko, et al. 2010 Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma J Neurooncol 100 1 95 103 20213332 10.1007/s11060-010-0143-7 1:CAS:528:DC%2BC3cXht1Krsb3E
-
(2010)
J Neurooncol
, vol.100
, Issue.1
, pp. 95-103
-
-
Phuphanich, S.1
Supko, J.G.2
-
17
-
-
79251545172
-
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78
-
21106982 10.1182/blood-2010-04-278853 1:CAS:528:DC%2BC3MXhvFGks7o%3D
-
G Roue P Perez-Galan, et al. 2011 The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78 Blood 117 4 1270 1279 21106982 10.1182/blood-2010-04-278853 1:CAS:528:DC%2BC3MXhvFGks7o%3D
-
(2011)
Blood
, vol.117
, Issue.4
, pp. 1270-1279
-
-
Roue, G.1
Perez-Galan, P.2
-
18
-
-
0035004169
-
Expression of nuclear factor-kappa B, tumor necrosis factor receptor type 1, and c-Myc in human astrocytomas
-
10.2176/nmc.41.187 1:STN:280:DC%2BD3M3psVymtg%3D%3D
-
S Hayashi M Yamamoto, et al. 2001 Expression of nuclear factor-kappa B, tumor necrosis factor receptor type 1, and c-Myc in human astrocytomas Neurol Med Chir (Tokyo) 41 4 187 195 10.2176/nmc.41.187 1:STN:280: DC%2BD3M3psVymtg%3D%3D
-
(2001)
Neurol Med Chir (Tokyo)
, vol.41
, Issue.4
, pp. 187-195
-
-
Hayashi, S.1
Yamamoto, M.2
-
19
-
-
34250645768
-
Bortezomib sensitizes primary human astrocytoma cells of WHO grades i to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
-
17545549 10.1158/1078-0432.CCR-07-0251 1:CAS:528:DC%2BD2sXmtVaisrc%3D
-
R Koschny H Holland, et al. 2007 Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis Clin Cancer Res 13 11 3403 3412 17545549 10.1158/1078-0432.CCR-07-0251 1:CAS:528:DC%2BD2sXmtVaisrc%3D
-
(2007)
Clin Cancer Res
, vol.13
, Issue.11
, pp. 3403-3412
-
-
Koschny, R.1
Holland, H.2
-
20
-
-
77951919034
-
Bmf is upregulated by PS-341-mediated cell death of glioma cells through JNK phosphorylation
-
19267218 10.1007/s11033-009-9491-9
-
Z Tianhu Z Shiguang, et al. 2010 Bmf is upregulated by PS-341-mediated cell death of glioma cells through JNK phosphorylation Mol Biol Rep 37 3 1211 1219 19267218 10.1007/s11033-009-9491-9
-
(2010)
Mol Biol Rep
, vol.37
, Issue.3
, pp. 1211-1219
-
-
Tianhu, Z.1
Shiguang, Z.2
-
21
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
12391322 10.1073/pnas.202445099 1:CAS:528:DC%2BD38XosF2iu7Y%3D
-
N Mitsiades CS Mitsiades, et al. 2002 Molecular sequelae of proteasome inhibition in human multiple myeloma cells Proc Natl Acad Sci USA 99 22 14374 14379 12391322 10.1073/pnas.202445099 1:CAS:528:DC%2BD38XosF2iu7Y%3D
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.22
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
-
22
-
-
0031297298
-
The heat-shock response: Regulation and function of heat-shock proteins and molecular chaperones
-
9493008 1:CAS:528:DyaK1cXktVSrsQ%3D%3D
-
RI Morimoto MP Kline, et al. 1997 The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones Essays Biochem 32 17 29 9493008 1:CAS:528:DyaK1cXktVSrsQ%3D%3D
-
(1997)
Essays Biochem
, vol.32
, pp. 17-29
-
-
Morimoto, R.I.1
Kline, M.P.2
-
23
-
-
0035138956
-
The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo
-
11205912 1:CAS:528:DC%2BD3MXht1Wht7s%3D
-
M Koishi S Yokota, et al. 2001 The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo Clin Cancer Res 7 1 215 219 11205912 1:CAS:528:DC%2BD3MXht1Wht7s%3D
-
(2001)
Clin Cancer Res
, vol.7
, Issue.1
, pp. 215-219
-
-
Koishi, M.1
Yokota, S.2
-
24
-
-
0031034160
-
Activation of the cell death program by inhibition of proteasome function
-
9023346 10.1073/pnas.94.3.855 1:CAS:528:DyaK2sXhtVOltLc%3D
-
HC Drexler 1997 Activation of the cell death program by inhibition of proteasome function Proc Natl Acad Sci USA 94 3 855 860 9023346 10.1073/pnas.94.3.855 1:CAS:528:DyaK2sXhtVOltLc%3D
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.3
, pp. 855-860
-
-
Drexler, H.C.1
-
25
-
-
0033059459
-
Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin
-
10354141 10.1046/j.1365-2141.1999.01388.x 1:CAS:528:DyaK1MXkt1Orur0%3D
-
Masdehors PS Omura, et al. 1999 Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin Br J Haematol 105 3 752 757 10354141 10.1046/j.1365-2141.1999.01388. x 1:CAS:528:DyaK1MXkt1Orur0%3D
-
(1999)
Br J Haematol
, vol.105
, Issue.3
, pp. 752-757
-
-
Masdehors1
Omura, P.S.2
-
26
-
-
33646441357
-
Bortezomib: Proteasome inhibition as an effective anticancer therapy
-
16555986 10.1517/14796694.1.2.161 1:CAS:528:DC%2BD2MXktlOmtb4%3D
-
PG Richardson C Mitsiades 2005 Bortezomib: proteasome inhibition as an effective anticancer therapy Future Oncol 1 2 161 171 16555986 10.1517/14796694.1.2.161 1:CAS:528:DC%2BD2MXktlOmtb4%3D
-
(2005)
Future Oncol
, vol.1
, Issue.2
, pp. 161-171
-
-
Richardson, P.G.1
Mitsiades, C.2
-
27
-
-
69349097803
-
Phase i study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma
-
19671864 10.1158/1078-0432.CCR-08-2850 1:CAS:528:DC%2BD1MXpvFeit7Y%3D
-
A Badros AM Burger, et al. 2009 Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma Clin Cancer Res 15 16 5250 5257 19671864 10.1158/1078-0432.CCR-08-2850 1:CAS:528:DC%2BD1MXpvFeit7Y%3D
-
(2009)
Clin Cancer Res
, vol.15
, Issue.16
, pp. 5250-5257
-
-
Badros, A.1
Burger, A.M.2
-
28
-
-
79952277220
-
MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity
-
20418664 10.1158/1535-7163.MCT-10-0471 1:CAS:528:DC%2BC3cXhtlKgt73M
-
MN Saha H Jiang, et al. 2010 MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity Cancer Biol Ther 9 11 936 944 20418664 10.1158/1535-7163.MCT-10-0471 1:CAS:528:DC%2BC3cXhtlKgt73M
-
(2010)
Cancer Biol Ther
, vol.9
, Issue.11
, pp. 936-944
-
-
Saha, M.N.1
Jiang, H.2
-
29
-
-
77955006485
-
Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells
-
20651984 1:CAS:528:DC%2BC3cXovFGrtrg%3D
-
S Meister B Frey, et al. 2010 Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells Neoplasia 12 7 550 561 20651984 1:CAS:528:DC%2BC3cXovFGrtrg%3D
-
(2010)
Neoplasia
, vol.12
, Issue.7
, pp. 550-561
-
-
Meister, S.1
Frey, B.2
-
30
-
-
77951257992
-
Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells
-
19838833 10.1007/s12192-009-0147-4 1:CAS:528:DC%2BC3cXktlSit7o%3D
-
JT Young JJ Heikkila 2010 Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells Cell Stress Chaperones 15 3 323 334 19838833 10.1007/s12192-009-0147-4 1:CAS:528:DC%2BC3cXktlSit7o%3D
-
(2010)
Cell Stress Chaperones
, vol.15
, Issue.3
, pp. 323-334
-
-
Young, J.T.1
Heikkila, J.J.2
-
31
-
-
57349152434
-
Bortezomib-induced survival signals and genes in human proximal tubular cells
-
18776064 10.1124/jpet.108.142604
-
R Sarkozi P Perco, et al. 2008 Bortezomib-induced survival signals and genes in human proximal tubular cells J Pharmacol Exp Ther 327 3 645 656 18776064 10.1124/jpet.108.142604
-
(2008)
J Pharmacol Exp Ther
, vol.327
, Issue.3
, pp. 645-656
-
-
Sarkozi, R.1
Perco, P.2
-
32
-
-
0035254227
-
Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase
-
11157751 10.1093/emboj/20.3.446 1:CAS:528:DC%2BD3MXitFGqtrY%3D
-
HS Park JS Lee, et al. 2001 Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase EMBO J 20 3 446 456 11157751 10.1093/emboj/20.3.446 1:CAS:528:DC%2BD3MXitFGqtrY%3D
-
(2001)
EMBO J
, vol.20
, Issue.3
, pp. 446-456
-
-
Park, H.S.1
Lee, J.S.2
-
33
-
-
0032932192
-
Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: A novel pathway controlled by HSP72
-
10082520 1:CAS:528:DyaK1MXit1amsb0%3D
-
AB Meriin JA Yaglom, et al. 1999 Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72 Mol Cell Biol 19 4 2547 2555 10082520 1:CAS:528: DyaK1MXit1amsb0%3D
-
(1999)
Mol Cell Biol
, vol.19
, Issue.4
, pp. 2547-2555
-
-
Meriin, A.B.1
Yaglom, J.A.2
|