Iterative design of peptide-based hydrogels and the effect of network electrostatics on primary chondrocyte behavior

Biomaterials

Volumn 33, Issue 30, 2012, Pages 7478-7488

  Sinthuvanich, Chomdao ^a,b   Haines Butterick, Lisa A ^b   Nagy, Katelyn J ^a,b   Schneider, Joel P ^a  

^a FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

Author keywords

Cell delivery; Chondrocyte; Hydrogel; Peptide; Self assembly; Tissue engineering

Indexed keywords

BULK MECHANICAL PROPERTIES; CELL DELIVERY; CELL VIABILITY; CHARGE STATE; CHONDROCYTES; CHONDROCYTIC; CULTURE TIME; EXTRACELLULAR MATRIX DEPOSITION; HYDROGEL NETWORKS; IN-VITRO; ITERATIVE DESIGN; LOCAL NETWORKS; MICROENVIRONMENTS; PEPTIDE DESIGN; RHEOLOGICAL BEHAVIORS; TYPE II COLLAGENS; VIABLE CELLS;

BODY FLUIDS; CELL DEATH; DISSOCIATION; ELECTROSTATICS; GENE EXPRESSION; HYDROGELS; ORGANIC POLYMERS; PEPTIDES; SELF ASSEMBLY; TISSUE ENGINEERING;

CELL CULTURE;

COLLAGEN TYPE 1; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; HLT2 PEPTIDE; MAX8 PEPTIDE; MONOMER; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; ENCAPSULATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HYDROGEL; IN VITRO STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STATIC ELECTRICITY; TISSUE ENGINEERING;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; ELASTIC MODULUS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCANS; HYDROGELS; MOLECULAR SEQUENCE DATA; PEPTIDES; RHEOLOGY; STATIC ELECTRICITY;

EID: 84864990683     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.06.097     Document Type: Article

References (36)

1. Vaquero J., Forriol F. Knee chondral injuries: clinical treatment strategies and experimental models. Injury 2012, 43(6):694-705.
2. Farr J., Cole B., Dhawan A., Kercher J., Sherman S. Clinical cartilage restoration: evolution and overview. Clin Orthop Relat Res 2011, 469(10):2696-2705.
3. Brittberg M., Lindahl A., Nilsson A., Ohlsson C., Isaksson O., Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994, 331(14):889-895.
4. Riegger-Krugh C.L., Mccarty E.C., Robinson M.S., Wegzyn D.A. Autologous chondrocyte implantation: current surgery and rehabilitation. Med Sci Sports Exerc 2008, 40(2):206-214.
5. Iwasa J., Engebretsen L., Shima Y., Ochi M. Clinical application of scaffolds for cartilage tissue engineering. Knee Surg Sports Traumatol Arthrosc 2009, 17(6):561-577.
6. Amini A.A., Nair L.S. Injectable hydrogels for bone and cartilage repair. Biomed Mater 2012, 7(2).
7. Zheng Shu X., Liu Y., Palumbo F.S., Luo Y., Prestwich G.D. In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials 2004, 25(7-8):1339-1348.
8. Aguado B.A., Mulyasasmita W., Su J., Lampe K.J., Heilshorn S.C. Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. Tissue Eng Part A 2011, 18(7-8):806-815.
9. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126(4):677-689.
10. Haines-Butterick L., Rajagopal K., Branco M., Salick D., Rughani R., Pilarz M., et al. Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells. Proc Natl Acad Sci U S A 2007, 104(19):7791-7796.
11. Yan C., Mackay M.E., Czymmek K., Nagarkar R.P., Schneider J.P., Pochan D.J. Injectable solid peptide hydrogel as a cell carrier: effects of shear flow on hydrogels and cell payload. Langmuir 2012, 28(14):6076-6087.
12. Schneider J.P., Pochan D.J., Ozbas B., Rajagopal K., Pakstis L., Kretsinger J. Responsive hydrogels from the intramolecular folding and self-assembly of a designed peptide. J Am Chem Soc 2002, 124(50):15030-15037.
13. Rajagopal K., Lamm M.S., Haines-Butterick L.A., Pochan D.J., Schneider J.P. Tuning the pH responsiveness of β-hairpin peptide folding, self-assembly, and hydrogel material formation. Biomacromolecules 2009, 10(9):2619-2625.
14. Branco M.C., Pochan D.J., Wagner N.J., Schneider J.P. The effect of protein structure on their controlled release from an injectable peptide hydrogel. Biomaterials 2010, 31(36):9527-9534.
15. Fischer D., Li Y., Ahlemeyer B., Krieglstein J., Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 2003, 24(7):1121-1131.
16. Schneider G.B., English A., Abraham M., Zaharias R., Stanford C., Keller J. The effect of hydrogel charge density on cell attachment. Biomaterials 2004, 25(15):3023-3028.
17. Xu Y., Takai M., Ishihara K. Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces. Biomaterials 2009, 30(28):4930-4938.
18. Keselowsky B.G., Collard D.M., García A.J. Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding. Biomaterials 2004, 25(28):5947-5954.
19. Chen Y.M., Gong J.P., Tanaka M., Yasuda K., Yamamoto S., Shimomura M., et al. Tuning of cell proliferation on tough gels by critical charge effect. J Biomed Mater Res A 2009, 88A(1):74-83.
20. Dadsetan M., Pumberger M., Casper M.E., Shogren K., Giuliani M., Ruesink T., et al. The effects of fixed electrical charge on chondrocyte behavior. Acta Biomater 2011, 7(5):2080-2090.
21. Guo L., Kawazoe N., Hoshiba T., Tateishi T., Chen G., Zhang X. Osteogenic differentiation of human mesenchymal stem cells on chargeable polymer-modified surfaces. J Biomed Mater Res A 2008, 87A(4):903-912.
22. Hoemann C.D., Sun J., Chrzanowski V., Buschmann M.D. A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage. Anal Biochem 2002, 300(1):1-10.
23. Labarca C., Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980, 102(2):344-352.
24. Chandrasekhar S., Esterman M.A., Hoffman H.A. Microdetermination of proteoglycans and glycosaminoglycans in the presence of guanidine hydrochloride. Anal Biochem 1987, 161(1):103-108.
25. Kesava Reddy G., Enwemeka C.S. A simplified method for the analysis of hydroxyproline in biological tissues. Clin Biochem 1996, 29(3):225-229.
26. Ignat'eva N., Danilov N., Averkiev S., Obrezkova M., Lunin V., Sobol' E. Determination of hydroxyproline in tissues and the evaluation of the collagen content of the tissues. J Anal Chem 2007, 62(1):51-57.
27. Fitzgerald J.B., Jin M., Grodzinsky A.J. Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue. J Biol Chem 2006, 281(34):24095-24103.
28. -ΔΔCT Method. Methods 2001, 25(4):402-408.
29. Minor D.L., Kim P.S. Measurement of the β-sheet-forming propensities of amino acids. Nature 1994, 367(6464):660-663.
30. Wouters M.A., Curmi P.M.G. An analysis of side chain interactions and pair correlations within antiparallel β-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs. Proteins Struct Funct Bioinformat 1995, 22(2):119-131.
31. Kim Y.-J., Sah R.L.Y., Doong J.-Y.H., Grodzinsky A.J. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 1988, 174(1):168-176.
32. Lin Z., Fitzgerald J.B., Xu J., Willers C., Wood D., Grodzinsky A.J., et al. Gene expression profiles of human chondrocytes during passaged monolayer cultivation. J Orthop Res 2008, 26(9):1230-1237.
33. Schuh E., Hofmann S., Stok K., Notbohm H., Müller R., Rotter N. Chondrocyte redifferentiation in 3D: the effect of adhesion site density and substrate elasticity. J Biomed Mater Res A 2012, 100A(1):38-47.
34. Hoemann C.D., Sun J., Légaré A., McKee M.D., Buschmann M.D. Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthritis Cartilage 2005, 13(4):318-329.
35. Tare R.S., Howard D., Pound J.C., Roach H.I., Oreffo R.O.C. Tissue engineering strategies for cartilage generation-Micromass and three dimensional cultures using human chondrocytes and a continuous cell line. Biochem Biophys Res Commun 2005, 333(2):609-621.
36. Akmal M., Anand A., Anand B., Wiseman M., Goodship A.E., Bentley G. The culture of articular chondrocytes in hydrogel constructs within a bioreactor enhances cell proliferation and matrix synthesis. J Bone Jt Surg Br 2006, 88-B(4):544-553.