Enhanced cartilage formation by inhibiting cathepsin K expression in chondrocytes expanded in vitro

Biomaterials

Volumn 33, Issue 30, 2012, Pages 7394-7404

  Zhang, Yan ^a   Li, Jie ^a   Zhu, Ji ^a   Zhou, Guangdong ^a   Zhang, Wen Jie ^a   Cao, Yilin ^a   Liu, Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cartilage engineering; Cathepsin K; Chondrocytes; RNA interference

Indexed keywords

CARTILAGE ENGINEERING; CARTILAGE FORMATION; CARTILAGE REGENERATION; CHONDROCYTES; CHONDROGENIC PHENOTYPES; CLINICAL APPLICATION; CLINICAL TRANSLATION; COLLAGEN II; CONTROL GROUPS; CONTROL-CELL; ENGINEERED CARTILAGE; EXPERIMENTAL GROUPS; GENE MODIFICATION; GLYCOSAMINOGLYCANS; HUMAN CARTILAGE; HUMAN CHONDROCYTES; IN-VITRO; IN-VIVO; OVER-EXPRESSION; PLURONIC F-127; PROTEIN EXPRESSIONS; PROTEOGLYCANS; REDUCED MATRIX; RNA INTERFERENCE;

BODY FLUIDS; CELLS; COLLAGEN; CYTOLOGY; GENE EXPRESSION; GENETIC ENGINEERING; GLYCOPROTEINS; POLYMERASE CHAIN REACTION; RNA;

CARTILAGE;

CATHEPSIN K; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; SMALL INTERFERING RNA;

ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TISSUE ENGINEERING; WESTERN BLOTTING;

ANIMALS; CARTILAGE; CATHEPSIN K; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; LENTIVIRUS; MICE; MICE, NUDE; PHENOTYPE; PLASMIDS; RNA INTERFERENCE; STAINING AND LABELING;

EID: 84864983303     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.06.070     Document Type: Article

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