Antimicrobial activity of adenine-based inhibitors of NAD +-dependent DNA ligase

ACS Medicinal Chemistry Letters

Volumn 3, Issue 8, 2012, Pages 663-667

  Buurman, Ed T ^a   Laganas, Valerie A ^a   Liu, Ce Feng ^a,b   Manchester, John I ^a  

^a ASTRAZENECA   (United Kingdom)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

antimicrobial; biochemical potency; efflux; LigA; mode of action; permeance

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CELL ENLARGEMENT; DRUG POTENCY; HAEMOPHILUS INFLUENZAE; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

EID: 84864973325     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300169x     Document Type: Article

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