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Volumn 13, Issue 1, 2012, Pages

In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish

Author keywords

Blood brain barrier; Blood retinal barrier; Fluorescent indoline derivatives; Transporters; Zebrafish

Indexed keywords

CARBENE; DIAGNOSTIC AGENT; INDOLE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; UNCLASSIFIED DRUG; VERLUKAST; ZMB 034; ZMB 740; ZMB 996; ZMC 213; ZMC 808; ZMJ 018; ZMJ O18;

EID: 84864948753     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-13-101     Document Type: Article
Times cited : (41)

References (42)
  • 1
    • 22744440362 scopus 로고    scopus 로고
    • Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
    • 10.1016/j.pneurobio.2005.04.006, 16011870
    • Loscher W, Potschka H. Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases. Prog Neurobiol 2005, 76(1):22-76. 10.1016/j.pneurobio.2005.04.006, 16011870.
    • (2005) Prog Neurobiol , vol.76 , Issue.1 , pp. 22-76
    • Loscher, W.1    Potschka, H.2
  • 2
    • 33845937770 scopus 로고    scopus 로고
    • Structure-brain exposure relationships
    • 10.1021/jm060642i, 17181137
    • Hitchcock SA, Pennington LD. Structure-brain exposure relationships. J Med Chem 2006, 49(26):7559-7583. 10.1021/jm060642i, 17181137.
    • (2006) J Med Chem , vol.49 , Issue.26 , pp. 7559-7583
    • Hitchcock, S.A.1    Pennington, L.D.2
  • 3
    • 33845784758 scopus 로고    scopus 로고
    • Blood-brain barrier delivery
    • Pardridge WM. Blood-brain barrier delivery. Drug Discov Today 2007, 12(1-2):54-61.
    • (2007) Drug Discov Today , vol.12 , Issue.1-2 , pp. 54-61
    • Pardridge, W.M.1
  • 4
    • 44949250688 scopus 로고    scopus 로고
    • Blood-brain barrier permeability considerations for CNS-targeted compound library design
    • 10.1016/j.cbpa.2008.03.019, 18435937
    • Hitchcock SA. Blood-brain barrier permeability considerations for CNS-targeted compound library design. Curr Opin Chem Biol 2008, 12(3):318-323. 10.1016/j.cbpa.2008.03.019, 18435937.
    • (2008) Curr Opin Chem Biol , vol.12 , Issue.3 , pp. 318-323
    • Hitchcock, S.A.1
  • 6
    • 72449185642 scopus 로고    scopus 로고
    • Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept
    • 10.1002/cbdv.200900103, 19937839
    • Reichel A. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept. Chem Biodivers 2009, 6(11):2030-2049. 10.1002/cbdv.200900103, 19937839.
    • (2009) Chem Biodivers , vol.6 , Issue.11 , pp. 2030-2049
    • Reichel, A.1
  • 7
    • 65749100582 scopus 로고    scopus 로고
    • Drug interactions at the blood-brain barrier: fact or fantasy?
    • 10.1016/j.pharmthera.2009.03.017, 2751796, 19393264
    • Eyal S, Hsiao P, Unadkat JD. Drug interactions at the blood-brain barrier: fact or fantasy?. Pharmacol Ther 2009, 123(1):80-104. 10.1016/j.pharmthera.2009.03.017, 2751796, 19393264.
    • (2009) Pharmacol Ther , vol.123 , Issue.1 , pp. 80-104
    • Eyal, S.1    Hsiao, P.2    Unadkat, J.D.3
  • 8
    • 70449526541 scopus 로고    scopus 로고
    • Assessment of the blood-brain barrier in CNS drug discovery
    • 10.1016/j.nbd.2009.07.033, 19664709
    • Jeffrey P, Summerfield S. Assessment of the blood-brain barrier in CNS drug discovery. Neurobiol Dis 2010, 37(1):33-37. 10.1016/j.nbd.2009.07.033, 19664709.
    • (2010) Neurobiol Dis , vol.37 , Issue.1 , pp. 33-37
    • Jeffrey, P.1    Summerfield, S.2
  • 9
    • 70350223814 scopus 로고    scopus 로고
    • Blood-brain barrier transporters and response to CNS-active drugs
    • 10.1007/s00228-009-0714-8, 19727692
    • Urquhart BL, Kim RB. Blood-brain barrier transporters and response to CNS-active drugs. Eur J Clin Pharmacol 2009, 65(11):1063-1070. 10.1007/s00228-009-0714-8, 19727692.
    • (2009) Eur J Clin Pharmacol , vol.65 , Issue.11 , pp. 1063-1070
    • Urquhart, B.L.1    Kim, R.B.2
  • 10
    • 71649107843 scopus 로고    scopus 로고
    • In vivo, in vitro and in silico methods for small molecule transfer across the BBB
    • 10.1002/jps.21745, 19408294
    • Mensch J, Oyarzabal J, Mackie C, Augustijns P. In vivo, in vitro and in silico methods for small molecule transfer across the BBB. J Pharm Sci 2009, 98(12):4429-4468. 10.1002/jps.21745, 19408294.
    • (2009) J Pharm Sci , vol.98 , Issue.12 , pp. 4429-4468
    • Mensch, J.1    Oyarzabal, J.2    Mackie, C.3    Augustijns, P.4
  • 11
    • 83055186554 scopus 로고    scopus 로고
    • Diversity-oriented optical imaging probe development
    • 10.1016/j.cbpa.2011.10.007, 22055497
    • Lee JS, Vendrell M, Chang YT. Diversity-oriented optical imaging probe development. Curr Opin Chem Biol 2011, 15(6):760-7. 10.1016/j.cbpa.2011.10.007, 22055497.
    • (2011) Curr Opin Chem Biol , vol.15 , Issue.6 , pp. 760-767
    • Lee, J.S.1    Vendrell, M.2    Chang, Y.T.3
  • 12
    • 40749095640 scopus 로고    scopus 로고
    • Functional and developmental analysis of the blood-brain barrier in zebrafish
    • 10.1016/j.brainresbull.2007.10.043, 18355638
    • Jeong JY, Kwon HB, Ahn JC, Kang D, Kwon SH, Park JA, Kim KW. Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull 2008, 75(5):619-628. 10.1016/j.brainresbull.2007.10.043, 18355638.
    • (2008) Brain Res Bull , vol.75 , Issue.5 , pp. 619-628
    • Jeong, J.Y.1    Kwon, H.B.2    Ahn, J.C.3    Kang, D.4    Kwon, S.H.5    Park, J.A.6    Kim, K.W.7
  • 13
    • 77954765192 scopus 로고    scopus 로고
    • A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development
    • 10.1186/1471-213X-10-76, 2914679, 20653957
    • Xie J, Farage E, Sugimoto M, Anand-Apte B. A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC Dev Biol 2010, 10:76. 10.1186/1471-213X-10-76, 2914679, 20653957.
    • (2010) BMC Dev Biol , vol.10 , pp. 76
    • Xie, J.1    Farage, E.2    Sugimoto, M.3    Anand-Apte, B.4
  • 14
    • 78650887526 scopus 로고    scopus 로고
    • Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo
    • 10.1002/ana.22318, 21194153
    • Zheng PP, Romme E, van der Spek PJ, Dirven CM, Willemsen R, Kros JM. Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo. Ann Neurol 2010, 68(6):835-844. 10.1002/ana.22318, 21194153.
    • (2010) Ann Neurol , vol.68 , Issue.6 , pp. 835-844
    • Zheng, P.P.1    Romme, E.2    van der Spek, P.J.3    Dirven, C.M.4    Willemsen, R.5    Kros, J.M.6
  • 16
    • 79957645785 scopus 로고    scopus 로고
    • Characterization of genetically targeted neuron types in the zebrafish optic tectum
    • 3046383, 21390291
    • Robles E, Smith SJ, Baier H. Characterization of genetically targeted neuron types in the zebrafish optic tectum. Front Neural Circuits 2011, 5:1. 3046383, 21390291.
    • (2011) Front Neural Circuits , vol.5 , pp. 1
    • Robles, E.1    Smith, S.J.2    Baier, H.3
  • 17
    • 79951576611 scopus 로고    scopus 로고
    • Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish
    • 10.1007/s11033-010-0283-z, 20842442
    • Long Y, Li Q, Cui Z. Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish. Mol Biol Rep 2011, 38(3):1703-1711. 10.1007/s11033-010-0283-z, 20842442.
    • (2011) Mol Biol Rep , vol.38 , Issue.3 , pp. 1703-1711
    • Long, Y.1    Li, Q.2    Cui, Z.3
  • 18
    • 79951514073 scopus 로고    scopus 로고
    • MRP proteins as potential mediators of heavy metal resistance in zebrafish cells
    • 10.1016/j.cbpc.2010.12.001, 21147257
    • Long Y, Li Q, Wang Y, Cui Z. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. Comp Biochem Physiol C Toxicol Pharmacol 2011, 153(3):310-317. 10.1016/j.cbpc.2010.12.001, 21147257.
    • (2011) Comp Biochem Physiol C Toxicol Pharmacol , vol.153 , Issue.3 , pp. 310-317
    • Long, Y.1    Li, Q.2    Wang, Y.3    Cui, Z.4
  • 19
    • 84861458112 scopus 로고    scopus 로고
    • Using Zebrafish to unravel the genetics of complex brain disorders
    • Gerlai R. Using Zebrafish to unravel the genetics of complex brain disorders. Curr Top Behav Neurosci 2012, 12:3-24.
    • (2012) Curr Top Behav Neurosci , vol.12 , pp. 3-24
    • Gerlai, R.1
  • 20
    • 84856977139 scopus 로고    scopus 로고
    • Fear, anxiety, and control in the zebrafish
    • 10.1002/dneu.20873, 22328274
    • Jesuthasan S. Fear, anxiety, and control in the zebrafish. Dev Neurobiol 2012, 72(3):395-403. 10.1002/dneu.20873, 22328274.
    • (2012) Dev Neurobiol , vol.72 , Issue.3 , pp. 395-403
    • Jesuthasan, S.1
  • 21
    • 33745551200 scopus 로고    scopus 로고
    • The zebrafish as a model for behavioral studies
    • 10.1089/zeb.2006.3.227, 18248263
    • Miklosi A, Andrew RJ. The zebrafish as a model for behavioral studies. Zebrafish 2006, 3(2):227-234. 10.1089/zeb.2006.3.227, 18248263.
    • (2006) Zebrafish , vol.3 , Issue.2 , pp. 227-234
    • Miklosi, A.1    Andrew, R.J.2
  • 22
    • 0242291084 scopus 로고    scopus 로고
    • Can zebrafish be used as a model to study the neurodevelopmental causes of autism?
    • 10.1034/j.1601-183X.2003.00038.x, 14606692
    • Tropepe V, Sive HL. Can zebrafish be used as a model to study the neurodevelopmental causes of autism?. Genes Brain Behav 2003, 2(5):268-281. 10.1034/j.1601-183X.2003.00038.x, 14606692.
    • (2003) Genes Brain Behav , vol.2 , Issue.5 , pp. 268-281
    • Tropepe, V.1    Sive, H.L.2
  • 23
  • 24
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • 10.1038/nrd1606, 15688071
    • Zon LI, Peterson RT. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 2005, 4(1):35-44. 10.1038/nrd1606, 15688071.
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.1 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2
  • 25
    • 80052979061 scopus 로고    scopus 로고
    • Zebrafish: as an integrative model for twenty-first century toxicity testing
    • 10.1002/bdrc.20214, 21932434
    • Sipes NS, Padilla S, Knudsen TB. Zebrafish: as an integrative model for twenty-first century toxicity testing. Birth Defects Res C Embryo Today 2011, 93(3):256-267. 10.1002/bdrc.20214, 21932434.
    • (2011) Birth Defects Res C Embryo Today , vol.93 , Issue.3 , pp. 256-267
    • Sipes, N.S.1    Padilla, S.2    Knudsen, T.B.3
  • 26
    • 33744905217 scopus 로고    scopus 로고
    • Evolution of the vertebrate ABC gene family: analysis of gene birth and death
    • 10.1016/j.ygeno.2006.03.001, 16631343
    • Annilo T, Chen ZQ, Shulenin S, Costantino J, Thomas L, Lou H, Stefanov S, Dean M. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Genomics 2006, 88(1):1-11. 10.1016/j.ygeno.2006.03.001, 16631343.
    • (2006) Genomics , vol.88 , Issue.1 , pp. 1-11
    • Annilo, T.1    Chen, Z.Q.2    Shulenin, S.3    Costantino, J.4    Thomas, L.5    Lou, H.6    Stefanov, S.7    Dean, M.8
  • 27
    • 0141854080 scopus 로고    scopus 로고
    • Functional expression of the multidrug resistance protein 1 in microglia
    • 10.1124/jpet.103.054304, 12893836
    • Dallas S, Zhu X, Baruchel S, Schlichter L, Bendayan R. Functional expression of the multidrug resistance protein 1 in microglia. J Pharmacol Exp Ther 2003, 307(1):282-290. 10.1124/jpet.103.054304, 12893836.
    • (2003) J Pharmacol Exp Ther , vol.307 , Issue.1 , pp. 282-290
    • Dallas, S.1    Zhu, X.2    Baruchel, S.3    Schlichter, L.4    Bendayan, R.5
  • 29
    • 42449100856 scopus 로고    scopus 로고
    • Progress in brain penetration evaluation in drug discovery and development
    • 10.1124/jpet.107.130294, 18203948
    • Liu X, Chen C, Smith BJ. Progress in brain penetration evaluation in drug discovery and development. J Pharmacol Exp Ther 2008, 325(2):349-356. 10.1124/jpet.107.130294, 18203948.
    • (2008) J Pharmacol Exp Ther , vol.325 , Issue.2 , pp. 349-356
    • Liu, X.1    Chen, C.2    Smith, B.J.3
  • 30
    • 0034998423 scopus 로고    scopus 로고
    • Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain
    • Sun H, Bungay PM, Elmquist WF. Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain. J Pharmacol Exp Ther 2001, 297(3):991-1000.
    • (2001) J Pharmacol Exp Ther , vol.297 , Issue.3 , pp. 991-1000
    • Sun, H.1    Bungay, P.M.2    Elmquist, W.F.3
  • 31
    • 80054735053 scopus 로고    scopus 로고
    • Assessment of P-glycoprotein activity in the Blood-brain Barrier (BBB) using Near Infrared Fluorescence (NIRF) imaging techniques
    • 10.1007/s11095-011-0478-6, 21598079
    • On NH, Chen F, Hinton M, Miller DW. Assessment of P-glycoprotein activity in the Blood-brain Barrier (BBB) using Near Infrared Fluorescence (NIRF) imaging techniques. Pharm Res 2011, 28(10):2505-2515. 10.1007/s11095-011-0478-6, 21598079.
    • (2011) Pharm Res , vol.28 , Issue.10 , pp. 2505-2515
    • On, N.H.1    Chen, F.2    Hinton, M.3    Miller, D.W.4
  • 32
    • 4644298314 scopus 로고    scopus 로고
    • High efficiency of dye-sensitized solar cells based on metal-free indoline dyes
    • 10.1021/ja0488277, 15453726
    • Horiuchi T, Miura H, Sumioka K, Uchida S. High efficiency of dye-sensitized solar cells based on metal-free indoline dyes. J Am Chem Soc 2004, 126(39):12218-12219. 10.1021/ja0488277, 15453726.
    • (2004) J Am Chem Soc , vol.126 , Issue.39 , pp. 12218-12219
    • Horiuchi, T.1    Miura, H.2    Sumioka, K.3    Uchida, S.4
  • 33
    • 16644375807 scopus 로고    scopus 로고
    • Discovery and use of small molecules for probing biological processes in zebrafish
    • Peterson RT, Fishman MC. Discovery and use of small molecules for probing biological processes in zebrafish. Methods Cell Biol 2004, 76:569-591.
    • (2004) Methods Cell Biol , vol.76 , pp. 569-591
    • Peterson, R.T.1    Fishman, M.C.2
  • 38
    • 0034669083 scopus 로고    scopus 로고
    • Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio
    • 10.1006/dbio.2000.9899, 11071756
    • Parichy DM, Mellgren EM, Rawls JF, Lopes SS, Kelsh RN, Johnson SL. Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio. Dev Biol 2000, 227(2):294-306. 10.1006/dbio.2000.9899, 11071756.
    • (2000) Dev Biol , vol.227 , Issue.2 , pp. 294-306
    • Parichy, D.M.1    Mellgren, E.M.2    Rawls, J.F.3    Lopes, S.S.4    Kelsh, R.N.5    Johnson, S.L.6
  • 40
    • 33749208496 scopus 로고    scopus 로고
    • Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
    • 10.1002/1097-0061(200012)17:4<294::AID-YEA54>3.0.CO;2-5, 2448381, 11119306
    • Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 2000, 17(4):294-301. 10.1002/1097-0061(200012)17:4<294::AID-YEA54>3.0.CO;2-5, 2448381, 11119306.
    • (2000) Yeast , vol.17 , Issue.4 , pp. 294-301
    • Nasevicius, A.1    Larson, J.2    Ekker, S.C.3
  • 41
    • 67650689042 scopus 로고    scopus 로고
    • Acute nicotine exposure and modulation of a spinal motor circuit in embryonic zebrafish
    • 10.1016/j.taap.2008.08.023, 19121331
    • Thomas LT, Welsh L, Galvez F, Svoboda KR. Acute nicotine exposure and modulation of a spinal motor circuit in embryonic zebrafish. Toxicol Appl Pharmacol 2009, 239(1):1-12. 10.1016/j.taap.2008.08.023, 19121331.
    • (2009) Toxicol Appl Pharmacol , vol.239 , Issue.1 , pp. 1-12
    • Thomas, L.T.1    Welsh, L.2    Galvez, F.3    Svoboda, K.R.4
  • 42
    • 77953687612 scopus 로고    scopus 로고
    • Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS)
    • 10.1016/j.aquatox.2010.02.003, 20171748
    • Huang H, Huang C, Wang L, Ye X, Bai C, Simonich MT, Tanguay RL, Dong Q. Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS). Aquat Toxicol 2010, 98(2):139-147. 10.1016/j.aquatox.2010.02.003, 20171748.
    • (2010) Aquat Toxicol , vol.98 , Issue.2 , pp. 139-147
    • Huang, H.1    Huang, C.2    Wang, L.3    Ye, X.4    Bai, C.5    Simonich, M.T.6    Tanguay, R.L.7    Dong, Q.8


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