Double allogenic mesenchymal stem cells transplantations could not enhance therapeutic effect compared with single transplantation in systemic lupus erythematosus

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Wang, Dandan ^a   Akiyama, Kentaro ^b   Zhang, Huayong ^a   Yamaza, Takayoshi ^b   Li, Xia ^a   Feng, Xuebing ^a   Wang, Hong ^a   Hua, Bingzhu ^a   Liu, Bujun ^a   Xu, Huji ^c   Chen, Wanjun ^d   Shi, Songtao ^b   Sun, Lingyun ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; COMPLEMENT COMPONENT C3; CREATININE; CYCLOPHOSPHAMIDE; DOUBLE STRANDED DNA ANTIBODY; HEMOGLOBIN; LEFLUNOMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE;

ADOLESCENT; ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; CHILD; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE DURATION; DISEASE FREE SURVIVAL; FEMALE; HERPES ZOSTER; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE INFECTION; KIDNEY FUNCTION; LUNG TUBERCULOSIS; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUTH INFECTION; MYCOSIS; OVERALL SURVIVAL; PNEUMONIA; PRIORITY JOURNAL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; REMISSION; SCHOOL CHILD; SURVIVAL RATE; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTE COUNT; TREATMENT OUTCOME; TREATMENT RESPONSE; UPPER RESPIRATORY TRACT INFECTION; CONTROLLED CLINICAL TRIAL; IMMUNOLOGY; MIDDLE AGED;

ADOLESCENT; ADULT; CHILD; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MIDDLE AGED; YOUNG ADULT;

EID: 84864948206     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/273291     Document Type: Article

References (31)

1. Houssiau F. A., Ginzler E. M., Current treatment of lupus nephritis Lupus 2008 17 5 426 430 (Pubitemid 351798721)
2. Karim M. Y., Pisoni C. N., Khamashta M. A., Update on immunotherapy for systemic lupus erythematosus-What's hot and what's not! Rheumatology 2009 48 4 332 341
3. Nauta A. J., Fibbe W. E., Immunomodulatory properties of mesenchymal stromal cells Blood 2007 110 10 3499 3506 (Pubitemid 350159613)
4. Singer N. G., Caplan A. I., Mesenchymal stem cells: mechanisms of inflammation Annual Review of Pathology: Mechanisms of Disease 2011 6 457 478
5. Hoogduijn M. J., Popp F., Verbeek R., Masoodi M., Nicolaou A., Baan C., Dahlke M. H., The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy International Immunopharmacology 2010 10 12 1496 1500
6. Calvi L. M., Adams G. B., Weibrecht K. W., Weber J. M., Olson D. P., Knight M. C., Martin R. P., Schipani E., Divieti P., Bringhurst F. R., Milner L. A., Kronenberg H. M., Scadden D. T., Osteoblastic cells regulate the haematopoietic stem cell niche Nature 2003 425 6960 841 846 (Pubitemid 37351468)
7. Uccelli A., Moretta L., Pistoia V., Mesenchymal stem cells in health and disease Nature Reviews Immunology 2008 8 9 726 736
8. Méndez-Ferrer S., Michurina T. V., Ferraro F., Mazloom A. R., MacArthur B. D., Lira S. A., Scadden D. T., Mag'Ayan A., Enikolopov G. N., Frenette P. S., Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 2010 466 7308 829 834
9. Peng L., Xie D. Y., Lin B. L., Liu J., Zhu H. P., Xie C., Zheng Y. B., Gao Z. L., Autologous bone marrow mesenchymal stem cell transplantation in liver failure patients caused by hepatitis B: short-term and long-term outcomes Hepatology 2011 54 3 820 828
10. Guiducci S., Porta F., Saccardi R., Guidi S., Ibba-Manneschi L., Manetti M., Mazzanti B., Dal Pozzo S., Milia A. F., Bellando-Randone S., Miniati I., Fiori G., Fontana R., Amanzi L., Braschi F., Bosi A., Matucci-Cerinic M., Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report Annals of Internal Medicine 2010 153 10 650 654
11. Liang J., Zhang H., Wang D., Feng X., Wang H., Hua B., Liu B., Sun L., Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease Gut 2012 61 3 468 469
12. Sun L., Wang D., Liang J., Zhang H., Feng X., Wang H., Hua B., Liu B., Ye S., Hu X., Xu W., Zeng X., Hou Y., Gilkeson G. S., Silver R. M., Lu L., Shi S., Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus Arthritis and Rheumatism 2010 62 8 2467 2475
13. Sun L., Akiyama K., Zhang H., Yamaza T., Hou Y., Zhao S., Xu T., Le A., Shi S., Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans Stem Cells 2009 27 6 1421 1432
14. Liang J., Zhang H., Hua B., Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study Annals of the Rheumatic Diseases 2010 69 8 1423 1429
15. Gu Z., Akiyama K., Ma X., Zhang H., Feng X., Yao G., Hou Y., Lu L., Gilkeson G. S., Silver R. M., Zeng X., Shi S., Sun L., Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice Lupus 2010 19 13 1502 1514
16. Smith E. L., Shmerling R. H., The American College of Rheumatology criteria for the classification of systemic lupus erythematosus: strengths, weaknesses, and opportunities for improvement Lupus 1999 8 8 586 595 (Pubitemid 29520523)
17. Jayne D., Passweg J., Marmont A., Farge D., Zhao X., Arnold R., Hiepe F., Lisukov I., Musso M., Ou-Yang J., Marsh J., Wulffraat N., Besalduch J., Bingham S. J., Emery P., Brune M., Fassas A., Faulkner L., Ferster A., Fiehn C., Fouillard L., Geromin A., Greinix H., Rabusin M., Saccardi R., Schneider P., Zintl F., Gratwohl A., Tyndall A., Autologous stem cell transplantation for systemic lupus erythematosus Lupus 2004 13 3 168 176 (Pubitemid 38478643)
18. Merrill J. T., Neuwelt C. M., Wallace D. J., Shanahan J. C., Latinis K. M., Oates J. C., Utset T. O., Gordon C., Isenberg D. A., Hsieh H. J., Zhang D., Brunetta P. G., Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial Arthritis and Rheumatism 2010 62 1 222 233
19. Le Blanc K., Frassoni F., Ball L., Locatelli F., Roelofs H., Lewis I., Lanino E., Sundberg B., Bernardo M. E., Remberger M., Dini G., Egeler R. M., Bacigalupo A., Fibbe W., Ringdén O., Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study The Lancet 2008 371 9624 1579 1586 (Pubitemid 351626841)
20. Zhou H., Guo M., Bian C., Sun Z., Yang Z., Zeng Y., Ai H., Zhao R. C., Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report Biology of Blood and Marrow Transplantation 2010 16 3 403 412
21. Lim J. H., Lee M. H., Yi H. G., Kim C. S., Kim J. H., Song S. U., Mesenchymal stromal cells for steroid-refractory acute graft-versus-host disease: a report of two cases International Journal of Hematology 2010 92 1 204 207
22. Mohamadnejad M., Alimoghaddam K., Mohyeddin-Bonab M., Bagheri M., Bashtar M., Ghanaati H., Baharvand H., Ghavamzadeh A., Malekzadeh R., Phase 1 trial of autologous bone marrow mesenchymal stem cell transplantation in patients with decompensated liver cirrhosis Archives of Iranian Medicine 2007 10 4 459 466 (Pubitemid 350001896)
23. Kharaziha P., Hellstrm P. M., Noorinayer B., Farzaneh F., Aghajani K., Jafari F., Telkabadi M., Atashi A., Honardoost M., Zali M. R., Soleimani M., Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial European Journal of Gastroenterology and Hepatology 2009 21 10 1199 1205
24. Martino G., Franklin R. J. M., Van Evercooren A. B., Kerr D. A., Stem cell transplantation in multiple sclerosis: current status and future prospects Nature Reviews Neurology 2010 6 5 247 255
25. English K., French A., Wood K. J., Mesenchymal stromal cells: facilitators of successful transplantation? Cell Stem Cell 2010 7 4 431 442
26. Freedman M. S., Bar-Or A., Atkins H. L., Karussis D., Frassoni F., Lazarus H., Scolding N., Slavin S., Le Blanc K., Uccelli A., The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the international MSCT study group Multiple Sclerosis 2010 16 4 503 510
27. Lee J. S., Hong J. M., Moon G. J., Lee P. H., Ahn Y. H., Bang O. Y., STARTING collaborators, A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke Stem Cells 2010 28 6 1099 1106
28. Zhou K., Zhang H., Jin O., Feng X., Yao G., Hou Y., Sun L., Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice Cellular and Molecular Immunology 2008 5 6 417 424
29. Uccelli A., Prockop D. J., Why should mesenchymal stem cells (MSCs) cure autoimmune diseases? Current Opinion in Immunology 2010 22 6 768 774
30. Kim J. A., Hong S., Lee B., Hong J. W., Kwak J. Y., Cho S., Kim C. C., The inhibition of T-cells proliferation by mouse mesenchymal stem cells through the induction of p16INK4A-cyclin D1/cdk4 and p21waf1, p27kip1-cyclin E/cdk2 pathways Cellular Immunology 2007 245 1 16 23 (Pubitemid 46776638)
31. Corcione A., Benvenuto F., Ferretti E., Giunti D., Cappiello V., Cazzanti F., Risso M., Gualandi F., Mancardi G. L., Pistoia V., Uccelli A., Human mesenchymal stem cells modulate B-cell functions Blood 2006 107 1 367 372 (Pubitemid 43053565)