Inhibition of aldose reductase by Gentiana lutea extracts

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Akileshwari, Chandrasekhar ^a   Muthenna, Puppala ^a   Nastasijevi, Branislav ^b   Joksi, Gordana ^b   Petrash, J Mark ^c   Reddy, Geereddy Bhanuprakash ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; AMAROGENTIN; BELLIDIFOLIN; BELLIDIFOLIN 8 O GLUCOSIDE; BELLIDIN; DEMETHYLBELLIDIFOLIN 8 O GLUCOSIDE; GENTIANA LUTEA EXTACT; GENTIANADINE; GENTIANINE; GENTIOPICRIN; GENTISIC ACID; GLUCOSE; GLUCOSIDE; ISOGENTISIN; ISOVITEXIN; LOGANIC ACID; PLANT EXTRACT; SORBITOL; SWEROSIDE; SWERTIAMARIN; SWERTIANOLIN; SWERTISIN; UNCLASSIFIED DRUG; AKR1B1 PROTEIN, HUMAN; ALR2 PROTEIN, RAT; IRIDOID; METHANOL;

ARTICLE; CONCENTRATION RESPONSE; DIABETES MELLITUS; DRUG MECHANISM; ENZYME INHIBITION; ERYTHROCYTE; GENTIAN; GENTIANA LUTEA; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOLECULAR DOCKING; MOLECULAR WEIGHT; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; BIOASSAY; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM;

ALDEHYDE REDUCTASE; ANIMALS; BIOLOGICAL ASSAY; ERYTHROCYTES; GENTIANA; GLUCOSE; HUMANS; IRIDOID GLYCOSIDES; IRIDOIDS; MALE; METHANOL; PLANT EXTRACTS; RATS; SORBITOL;

EID: 84864943704     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/147965     Document Type: Article

References (34)

1. Wild S., Roglic G., Green A., Sicree R., King H., Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 2007 27 5 1047 1053 (Pubitemid 38579764)
2. Brownlee M., Biochemistry and molecular cell biology of diabetic complications Nature 2001 414 6865 813 820 (Pubitemid 34000785)
3. Kinoshita J. H., A thirty year journey in the polyol pathway Experimental Eye Research 1990 50 6 567 573 (Pubitemid 20191282)
4. Bhatnagar A., Srivastava S. K., Aldose reductase: congenial and injurious profiles of an enigmatic enzyme Biochemical Medicine and Metabolic Biology 1992 48 2 91 121
5. Kador P. F., Kinoshita J. H., Sharpless N. E., Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications Journal of Medicinal Chemistry 1985 28 7 841 849 (Pubitemid 15012489)
6. Hotta N., Toyota T., Matsuoka K., Shigeta Y., Kikkawa R., Kaneko T., Takahashi A., Sugimura K., Koike Y., Ishii J., Sakamoto N., Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study Diabetes Care 2001 24 10 1776 1782 (Pubitemid 33716481)
7. Raskin P., Rosenstock J., Aldose reductase inhibitors and diabetic complications The American Journal of Medicine 1987 83 2 298 306
8. Pfeifer M. A., Schumer M. P., Gelber D. A., Aldose reductase inhibitors: the end of an era or the need for different trial designs? Diabetes 1997 46 supplement 2 S82 S89
9. Oates P. J., Mylari B. L., Aldose reductase inhibitors: therapeutic implications for diabetic complications Expert Opinion on Investigational Drugs 1999 8 12 2095 2119
10. Kador P. F., Robison W. G., Kinoshita J. H., The pharmacology of aldose reductase inhibitors Annual Review of Pharmacology and Toxicology 1985 25 691 714 (Pubitemid 15090999)
11. Suryanarayana P., Kumar P. A., Saraswat M., Petrash J. M., Reddy G. B., Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract Molecular Vision 2004 10 148 154 (Pubitemid 38658950)
12. Suryanarayana P., Saraswat M., Petrash J. M., Reddy G. B., Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats Molecular Vision 2007 24 1291 1297 (Pubitemid 47128953)
13. Saraswat M., Muthenna P., Suryanarayana P., Petrash J. M., Reddy G. B., Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications Asia Pacific Journal of Clinical Nutrition 2008 17 4 558 565
14. Muthenna P., Suryanarayana P., Gunda S., Petrash J. M., Reddy G. B., Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance FEBS Letters 2009 583 22 3637 3642
15. Reddy G. B., Muthenna P., Akileshwari C., Saraswat M., Petrash J. M., Inhibition of aldose reductase and sorbitol accumulation by dietary rutin Current Science 2011 101 9 1191 1197
16. Daniel M., Sabnis S. D., Chemical systematics of family Gentianaceae Current Science 1978 47 4 109 111
17. Petrash J. M., Harter T. M., Devine C. S., Olins P. O., Bhatnagar A., Liu S., Srivastava S. K., Involvement of cysteine residues in catalysis and inhibition of human aldose reductase. Site-directed mutagenesis of Cys-80, -298, and -303 The Journal of Biological Chemistry 1992 267 34 24833 24840
18. Malone J. I., Knox G., Benford S., Tedesco T. A., Red cell sorbitol: an indicator of diabetic control Diabetes 1980 29 11 861 864 (Pubitemid 11022281)
19. Hnsel R., Sticher O., Pharmakognosie-Phytopharmazie 2007 8 Heidelberg, Germany Springer
20. Wichtl M., Teedrogen und Phytotherapeutika 2002 4 Stuttgart, Germany Wissenschaftliche Verlagsgesellschaft mbH
21. Aberham A., Schwaiger S., Stuppner H., Ganzera M., Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS Journal of Pharmaceutical and Biomedical Analysis 2007 45 3 437 442 (Pubitemid 47588768)
22. ztrk N., Korkmaz S., ztrk Y., Baer K. H., Effects of gentiopicroside, sweroside and swertiamarine, secoiridoids from gentian (Gentiana lutea ssp. symphyandra), on cultured chicken embryonic fibroblasts Planta Medica 2006 72 4 289 294
23. Citov I., Ganzera M., Stuppner H., Solich P., Determination of gentisin, isogentisin, and amarogentin in Gentiana lutea L. by capillary electrophoresis Journal of Separation Science 2008 31 1 195 200 (Pubitemid 351227906)
24. Singh A., Phytochemicals of gentianaceae: a review of pharmacological properties International Journal of Pharmaceutical Sciences and Nanotechnology 2008 1 1 33 36
25. Schmieder A., Schwaiger S., Csordas A., Backovic A., Messner B., Wick G., Stuppner H., Bernhard D., Isogentisina novel compound for the prevention of smoking-caused endothelial injury Atherosclerosis 2007 194 2 317 325 (Pubitemid 47513093)
26. Crosas B., Hyndman D. J., Gallego O., Martras S., Parés X., Flynn T. G., Farrés J., Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism The Biochemical Journal 2003 373, part 3 973 979 (Pubitemid 36981109)
27. Morrison A. D., Clements R. S., Winegrad A. I., Effects of elevated glucose concentrations on the metabolism of the aortic wall The Journal of Clinical Investigation 1972 51 12 3114 3123
28. Reddy G. B., Satyanarayana A., Balakrishna N., Ayyagari R., Padma M., Viswanath K., Petrash J. M., Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy Molecular Vision 2008 14 593 601 (Pubitemid 351552305)
29. Tomlinson D. R., Stevens E. J., Diemel L. T., Aldose reductase inhibitors and their potential for the treatment of diabetic complications Trends in Pharmacological Sciences 1994 15 8 293 297 (Pubitemid 24245679)
30. ztrk N., Herekman-Demir T., ztrk Y., Bozan B., Baer K. H. C., Choleretic activity of Gentiana lutea ssp. symphyandra in rats Phytomedicine 1998 5 4 283 288 (Pubitemid 128566322)
31. Kuar A., Zupani A., entjurc M., Barievi D., Free radical scavenging activities of yellow gentian (Gentiana lutea L.) measured by electron spin resonance Human and Experimental Toxicology 2006 25 10 599 604
32. Mathew A., Taranalli A. D., Torgal S. S., Evaluation of anti-inflammatory and wound healing activity of Gentiana lutea rhizome extracts in animals Pharmaceutical Biology 2004 42 1 8 12 (Pubitemid 39564214)
33. Bruneton J., Pharmacognosy 1999 Paris, France Lavoisier Publishing
34. Hostettmann-Kaldas M., Hostettmann K., Sticher O., Xanthones, flavones and secoiridoids of American Gentiana species Phytochemistry 1981 20 3 443 446