High-performance liquid chromatography/tandem mass spectrometry for simultaneous determination of four dicaffeoylquinic acids in rat plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 903, Issue , 2012, Pages 177-181

  Sun, Yongbing ^a   Xu, Lan ^a   Wang, Qi ^a   He, Shuangfeng ^b   Huang, Hesong ^a   Zhang, Wugang ^a   Li, Gang ^c   Feng, Yulin ^a   Luo, Xiaojian ^a  

^a JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shijiazhuang Yiling Pharmaceutical Co Ltd   (China)

^c 94 Hospital of Nanjing Military Region   (China)

Author keywords

Dicaffeoylquinic acid; HPLC MS MS; Pharmacokinetics; Rat plasma

Indexed keywords

ANALYTES; CALIBRATION CURVES; CHINESE HERBS; CONCENTRATION RANGES; HPLC-MS/MS; LIQUID-LIQUID EXTRACTION; ORAL ADMINISTRATION; PLASMA SAMPLES; RAT PLASMA; RELATIVE ERRORS; SIMULTANEOUS DETERMINATIONS; TRIPLE-QUADRUPOLE MASS SPECTROMETRY; VALIDATED METHODS;

ELECTROSPRAY IONIZATION; MASS SPECTROMETRY; PHARMACOKINETICS;

BODY FLUIDS;

3,4 DICAFFEOYLQUINIC ACID; AINSLIAEA FRAGRANS CHAM EXTRACT; CYNARINE; ISOCHLOROGENIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CHINESE MEDICINE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RAT; TANDEM MASS SPECTROMETRY; TRIPLE QUADRUPOLE MASS SPECTROMETRY;

ANIMALS; CHLOROGENIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; DRUGS, CHINESE HERBAL; MALE; QUINIC ACID; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

AINSLIAEA; RATTUS;

EID: 84864929062     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.07.016     Document Type: Article

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