Inhibition of neurotoxic secretory phospholipases A 2 enzymatic, edematogenic, and myotoxic activities by harpalycin 2, an isoflavone isolated from Harpalyce brasiliana Benth

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Ximenes, Rafael M ^a   Rabello, Marcelo M ^b   Arajo, Renata M ^a,c   Silveira, Edilberto R ^a   Fagundes, Fbio H R ^d,e   Diz Filho, Eduardo B S ^d,e   Buzzo, Simone C ^d,e   Soares, Veronica C G ^d,e   Toyama, Daniela De O ^f   Gaeta, Henrique H ^e   Hernandes, Marcelo Z ^b   Monteiro, Helena S A ^a   Toyama, Marcos H ^e  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^d UNIVERSITY OF CAMPINAS   (Brazil)

^e SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^f MACKENZIE PRESBYTERIAN UNIVERSITY   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BEE VENOM; HARPALYCIN 2; ISOFLAVONE DERIVATIVE; PHOSPHOLIPASE A2; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BLOOD SAMPLING; BOTHROPS PIRAJA; COMPETITIVE INHIBITION; CONTROLLED STUDY; CROTALUS DURISSUS TERRIFICUS; EDEMA; ENZYME ACTIVITY; ENZYME SUBSTRATE; HARPALYCE BRASILIANA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HONEYBEE; HYDROGEN BOND; INSECT; MALE; MEDICINAL PLANT; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOUSE; NAJA NAJA; NEUROTOXICITY; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 84864921249     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/987517     Document Type: Article

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