메뉴 건너뛰기




Volumn 9, Issue 2, 2012, Pages 81-91

The neurohormonal network in the RAAS can bend before breaking

Author keywords

Aldosterone synthase inhibitor; Angiotensin converting enzyme inhibitor; Angiotensin receptor blocker; Angiotensin type 2 receptor agonist; Combination drug therapy; Direct renin inhibitor; Mineralocorticoid receptor blocker; Neurohormonal network; Renin angiotensin aldosterone system

Indexed keywords

ALDOSTERONE; ALISKIREN; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CANDESARTAN; CAPTOPRIL; CARVEDILOL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENZYME INHIBITOR; EPLERENONE; HORMONE RECEPTOR BLOCKING AGENT; LCI 699; LOSARTAN; METOPROLOL; MINERALOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR ANTAGONIST; NEUROHORMONE; PLACEBO; PRORENIN RECEPTOR BLOCKING AGENT; RAMIPRIL; RECEPTOR BLOCKING AGENT; RENIN INHIBITOR; SPIRONOLACTONE; TELMISARTAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSARTAN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CARDIOVASCULAR AGENT;

EID: 84864884864     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-012-0091-y     Document Type: Article
Times cited : (9)

References (75)
  • 1
    • 0023266532 scopus 로고
    • Results of the cooperative north scandinavian enalapril survival study (CONSENSUS)
    • Effects of enalapril on mortality in severe congestive heart failure. The CONSENSUS Trial Study Group
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med, 1987. 316(23): p. 1429-35.
    • (1987) N Engl J Med , vol.316 , Issue.23 , pp. 1429-1435
  • 2
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD investigators
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med, 1991. 325(5): p. 293-302.
    • (1991) N Engl J Med , vol.325 , Issue.5 , pp. 293-302
  • 3
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE investigators
    • Pfeffer MA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med. 1992;327(10):669-77.
    • (1992) N Engl J Med. , vol.327 , Issue.10 , pp. 669-677
    • Pfeffer, M.A.1
  • 4
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):145-53.
    • (2000) N Engl J Med. , vol.342 , Issue.3 , pp. 145-153
    • Yusuf, S.1
  • 5
    • 77956895723 scopus 로고    scopus 로고
    • Renin inhibitors in chronic heart failure: The Aliskiren Observation of Heart Failure Treatment study in context
    • Krum H, Maggioni A. Renin inhibitors in chronic heart failure: the Aliskiren Observation of Heart Failure Treatment study in context. Clin Cardiol. 2010;33(9):536-41.
    • (2010) Clin Cardiol , vol.33 , Issue.9 , pp. 536-541
    • Krum, H.1    Maggioni, A.2
  • 9
    • 78650399880 scopus 로고    scopus 로고
    • Eplerenone in patients with systolic heart failure and mild symptoms
    • Zannad F, et al. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011;364(1):11-21.
    • (2011) N Engl J Med , vol.364 , Issue.1 , pp. 11-21
    • Zannad, F.1
  • 10
    • 22544448655 scopus 로고    scopus 로고
    • The AT2 receptor - A matter of love and hate
    • DOI 10.1016/j.peptides.2005.03.010, PII S0196978105001257, International Symposium on Peptides Receptors, from Gene to Therapy
    • Steckelings UM, Kaschina E, Unger T. The AT2 receptor-a matter of love and hate. Peptides. 2005;26(8):1401-9. (Pubitemid 41021474)
    • (2005) Peptides , vol.26 , Issue.8 , pp. 1401-1409
    • Steckelings, U.M.1    Kaschina, E.2    Unger, Th.3
  • 11
    • 77950472601 scopus 로고    scopus 로고
    • Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB
    • This study reports the positive findings of in vitro application of the novel angiotensin II type 2 receptor agonist
    • Rompe, F., et al., Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension, 2010. 55(4): p. 924-31. This study reports the positive findings of in vitro application of the novel angiotensin II type 2 receptor agonist.
    • (2010) Hypertension , vol.55 , Issue.4 , pp. 924-931
    • Rompe, F.1
  • 15
    • 0027439938 scopus 로고
    • Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodiumdepleted rat
    • Macari D, et al. Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodiumdepleted rat. Eur J Pharmacol. 1993;249(1):85-93.
    • (1993) Eur J Pharmacol , vol.249 , Issue.1 , pp. 85-93
    • MacAri, D.1
  • 17
    • 58149375072 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor stimulation: A novel option of therapeutic interference with the reninangiotensin system in myocardial infarction?
    • Kaschina E, et al. Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the reninangiotensin system in myocardial infarction? Circulation. 2008;118(24):2523-32.
    • (2008) Circulation , vol.118 , Issue.24 , pp. 2523-2532
    • Kaschina, E.1
  • 19
    • 80255141746 scopus 로고    scopus 로고
    • Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: Results of a randomized, double-blind, placebo- and active-controlled phase 2 trial
    • This study is the first phase 2 clinical trial to provide evidence for the cardiovascular benefit of the novel aldosterone synthase inhibitor
    • Calhoun, D.A., et al., Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trial. Circulation, 2011. 124(18): p. 1945-55. This study is the first phase 2 clinical trial to provide evidence for the cardiovascular benefit of the novel aldosterone synthase inhibitor.
    • (2011) Circulation , vol.124 , Issue.18 , pp. 1945-1955
    • Calhoun, D.A.1
  • 20
    • 67349208215 scopus 로고    scopus 로고
    • New aspects of rapid aldosterone signaling
    • Grossmann C, Gekle M. New aspects of rapid aldosterone signaling. Mol Cell Endocrinol. 2009;308(1-2):53-62.
    • (2009) Mol Cell Endocrinol , vol.308 , Issue.1-2 , pp. 53-62
    • Grossmann, C.1    Gekle, M.2
  • 21
    • 34047222286 scopus 로고    scopus 로고
    • Nongenomic actions of aldosterone on the renal tubule
    • DOI 10.1161/01.HYP.0000259797.48382.b2
    • Good DW. Nongenomic actions of aldosterone on the renal tubule. Hypertension. 2007;49(4):728-39. (Pubitemid 351664211)
    • (2007) Hypertension , vol.49 , Issue.4 , pp. 728-739
    • Good, D.W.1
  • 22
    • 18144418605 scopus 로고    scopus 로고
    • Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system
    • DOI 10.1016/j.steroids.2005.02.004
    • Mihailidou AS, Funder JW. Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system. Steroids. 2005;70(5-7):347-51. (Pubitemid 40616031)
    • (2005) Steroids , vol.70 , Issue.5-7 SPEC. ISS. , pp. 347-351
    • Mihailidou, A.S.1    Funder, J.W.2
  • 23
    • 42649109044 scopus 로고    scopus 로고
    • Prorenin and (pro)renin receptor: A review of available data from in vitro studies and experimental models in rodents
    • DOI 10.1113/expphysiol.2007.040030
    • Nguyen G, Danser AH. Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents. Exp Physiol. 2008;93(5):557-63. (Pubitemid 351595066)
    • (2008) Experimental Physiology , vol.93 , Issue.5 , pp. 557-563
    • Nguyen, G.1    Danser, A.H.J.2
  • 28
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
    • DOI 10.1016/S0140-6736(07)61124-6, PII S0140673607611246
    • Oparil S, et al. Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, doubleblind trial. Lancet. 2007;370(9583):221-9. (Pubitemid 47069535)
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 29
    • 9644287897 scopus 로고    scopus 로고
    • Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
    • DOI 10.1097/01.ASN.0000146686.35541.29
    • Azizi M, et al. Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol. 2004;15(12):3126-33. (Pubitemid 39578845)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.12 , pp. 3126-3133
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyenne, T.-T.4    Bura-Riviere, A.5    Vaidyanathan, S.6    Camisasca, R.P.7
  • 30
    • 79959713470 scopus 로고    scopus 로고
    • Prognostic value of plasma renin activity in heart failure
    • Vergaro G, et al. Prognostic value of plasma renin activity in heart failure. Am J Cardiol. 2011;108(2):246-51.
    • (2011) Am J Cardiol , vol.108 , Issue.2 , pp. 246-251
    • Vergaro, G.1
  • 33
    • 50349094508 scopus 로고    scopus 로고
    • Aliskiren
    • Brown MJ. Aliskiren. Circulation. 2008;118(7):773-84.
    • (2008) Circulation , vol.118 , Issue.7 , pp. 773-784
    • Brown, M.J.1
  • 34
    • 57449084151 scopus 로고    scopus 로고
    • Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure
    • Westermann D, et al. Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressure. Hypertension. 2008;52(6):1068-75.
    • (2008) Hypertension , vol.52 , Issue.6 , pp. 1068-1075
    • Westermann, D.1
  • 36
    • 77956920177 scopus 로고    scopus 로고
    • The direct renin inhbitor, aliskerin, improves cardiac function via direct renin inhibition and via renin receptor modulation in a rodent model of diabetic diastolic heart failure
    • Abstract 6248
    • Connelly, K., et al., The direct renin inhbitor, aliskerin, improves cardiac function via direct renin inhibition and via renin receptor modulation in a rodent model of diabetic diastolic heart failure. Circulation, 2008. 118: p. S1166. Abstract 6248.
    • (2008) Circulation , vol.118
    • Connelly, K.1
  • 38
    • 79958249630 scopus 로고    scopus 로고
    • Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure
    • McMurray JJ, et al. Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure. Circ Heart Fail. 2008;1(1):17-24.
    • (2008) Circ Heart Fail , vol.1 , Issue.1 , pp. 17-24
    • McMurray, J.J.1
  • 39
    • 61349170589 scopus 로고    scopus 로고
    • Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy
    • Solomon SD, et al. Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy. Circulation. 2009;119(4):530-7.
    • (2009) Circulation , vol.119 , Issue.4 , pp. 530-537
    • Solomon, S.D.1
  • 40
    • 0032499670 scopus 로고    scopus 로고
    • Indications for ACE inhibitors in the early treatment of acute myocardial infarction: Systematic overview of individual data from 100, 000 patients in randomized trials
    • ACE Inhibitor Myocardial Infarction Collaborative Group
    • Indications for ACE inhibitors in the early treatment of acute myocardial infarction: systematic overview of individual data from 100,000 patients in randomized trials. ACE Inhibitor Myocardial Infarction Collaborative Group. Circulation, 1998. 97(22): p. 2202-12.
    • (1998) Circulation , vol.97 , Issue.22 , pp. 2202-2212
  • 41
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • DOI 10.1056/NEJMoa010713
    • Cohn JN, Tognoni G. A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure. N Engl J Med. 2001;345(23):1667-75. (Pubitemid 33126822)
    • (2001) New England Journal of Medicine , vol.345 , Issue.23 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 42
    • 0141892837 scopus 로고    scopus 로고
    • Effects of early and late administration of angiotensin-converting enzyme inhibitors on mortality after myocardial infarction
    • DOI 10.1016/S0002-9343(03)00435-2
    • Rodrigues EJ, Eisenberg MJ, Pilote L. Effects of early and late administration of angiotensin-converting enzyme inhibitors on mortality after myocardial infarction. Am J Med. 2003;115 (6):473-9. (Pubitemid 37237561)
    • (2003) American Journal of Medicine , vol.115 , Issue.6 , pp. 473-479
    • Rodrigues, E.J.1    Eisenberg, M.J.2    Pilote, L.3
  • 44
    • 0028998875 scopus 로고
    • When a question has an answer: Rationale for our early termination of the HEART Trial
    • Pfeffer MA, Hennekens CH. When a question has an answer: rationale for our early termination of the HEART Trial. Am J Cardiol. 1995;75(16):1173-5.
    • (1995) Am J Cardiol , vol.75 , Issue.16 , pp. 1173-1175
    • Pfeffer, M.A.1    Hennekens, C.H.2
  • 45
    • 0028819673 scopus 로고
    • ACE inhibitor use in patients with myocardial infarction. Summary of evidence from clinical trials
    • Latini R, et al. ACE inhibitor use in patients with myocardial infarction. Summary of evidence from clinical trials. Circulation. 1995;92(10):3132-7.
    • (1995) Circulation , vol.92 , Issue.10 , pp. 3132-3137
    • Latini, R.1
  • 46
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-added trial
    • DOI 10.1016/S0140-6736(03)14283-3
    • McMurray JJ, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003;362(9386):767-71. (Pubitemid 37093916)
    • (2003) Lancet , vol.362 , Issue.9386 , pp. 767-771
    • McMurray, J.J.V.1    Ostergren, J.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    Michelson, E.L.6    Olofsson, B.7    Yusuf, S.8    Pfeffer, M.A.9
  • 48
    • 41149101190 scopus 로고    scopus 로고
    • Safety and tolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: A systematic review and meta-analysis of randomized controlled trials
    • DOI 10.1016/j.cardfail.2007.11.008, PII S1071916407011591
    • Lakhdar R, Al-Mallah MH, Lanfear DE. Safety and tolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: a systematic review and meta-analysis of randomized controlled trials. J Card Fail. 2008;14(3):181-8. (Pubitemid 351434594)
    • (2008) Journal of Cardiac Failure , vol.14 , Issue.3 , pp. 181-188
    • Lakhdar, R.1    Al-Mallah, M.H.2    Lanfear, D.E.3
  • 49
    • 49149087718 scopus 로고    scopus 로고
    • Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): A multicentre, randomised, double-blind, controlled trial
    • Mann JF, et al. Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial. Lancet. 2008;372(9638):547-53.
    • (2008) Lancet , vol.372 , Issue.9638 , pp. 547-553
    • Mann, J.F.1
  • 50
    • 52449122086 scopus 로고    scopus 로고
    • Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways
    • Montezano AC, et al. Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol. 2008;28(8):1511-8.
    • (2008) Arterioscler Thromb Vasc Biol. , vol.28 , Issue.8 , pp. 1511-1518
    • Montezano, A.C.1
  • 51
    • 70349251477 scopus 로고    scopus 로고
    • Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice
    • Yamamoto E, et al. Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice. Hypertension. 2009;54(3):633-8.
    • (2009) Hypertension , vol.54 , Issue.3 , pp. 633-638
    • Yamamoto, E.1
  • 52
    • 77954383099 scopus 로고    scopus 로고
    • Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice
    • Dong YF, et al. Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice. J Hypertens. 2010;28 (7):1554-65.
    • (2010) J Hypertens , vol.28 , Issue.7 , pp. 1554-1565
    • Dong, Y.F.1
  • 55
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • Parving HH, et al. Aliskiren combined with losartan in type 2 diabetes and nephropathy. N Engl J Med. 2008;358(23):2433-46.
    • (2008) N Engl J Med , vol.358 , Issue.23 , pp. 2433-2446
    • Parving, H.H.1
  • 57
    • 33947182655 scopus 로고    scopus 로고
    • Aliskiren, an oral renin inhibitor, provides dosedependent efficacy and sustained 24-hour blood pressure control in patients with hypertension
    • Oh BH, et al. Aliskiren, an oral renin inhibitor, provides dosedependent efficacy and sustained 24-hour blood pressure control in patients with hypertension. J Am Coll Cardiol. 2007;49(11):1157-63.
    • (2007) J Am Coll Cardiol. , vol.49 , Issue.11 , pp. 1157-1163
    • Oh, B.H.1
  • 58
    • 3042731163 scopus 로고    scopus 로고
    • Serum aldosterone and the incidence of hypertension in nonhypertensive persons
    • Vasan RS, et al. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med. 2004;351(1):33-41.
    • (2004) N Engl J Med. , vol.351 , Issue.1 , pp. 33-41
    • Vasan, R.S.1
  • 59
    • 66549130863 scopus 로고    scopus 로고
    • Narrative review: The emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension
    • Sowers JR, Whaley-Connell A, Epstein M. Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension. Ann Intern Med. 2009;150(11):776-83.
    • (2009) Ann Intern Med , vol.150 , Issue.11 , pp. 776-783
    • Sowers, J.R.1    Whaley-Connell, A.2    Epstein, M.3
  • 61
    • 0022532461 scopus 로고
    • Interaction between the adrenergic and renin-angiotensin-aldosterone- systems
    • van Zwieten PA, de Jonge A. Interaction between the adrenergic and renin-angiotensin-aldosterone-systems. Postgrad Med J. 1986;62 Suppl 1:23-7. (Pubitemid 16057508)
    • (1986) Postgraduate Medical Journal , vol.62 , Issue.SUPPL. 1 , pp. 23-27
    • Van Zwieten, P.A.1    De Jonge, A.2
  • 62
    • 0021748527 scopus 로고
    • Interaction between sympathetic and renin-angiotensin system
    • DOI 10.1097/00004872-198412000-00002
    • Zimmerman BG, Sybertz EJ, Wong PC. Interaction between sympathetic and renin-angiotensin system. J Hypertens. 1984;2 (6):581-7. (Pubitemid 15188008)
    • (1984) Journal of Hypertension , vol.2 , Issue.6 , pp. 581-587
    • Zimmerman, B.G.1    Sybertz, E.J.2    Wong, P.C.3
  • 64
    • 0020583450 scopus 로고
    • Effect of captopril on sympathetic neurotransmission in pithed normotensive rats
    • De Jonge A, et al. Effect of captopril on sympathetic neurotransmission in pithed normotensive rats. Eur J Pharmacol. 1983;88(2-3):231-40. (Pubitemid 13121913)
    • (1983) European Journal of Pharmacology , vol.88 , Issue.2-3 , pp. 231-240
    • De Jonge, A.1    Knape, J.T.A.2    Van Meel, J.C.A.3
  • 65
    • 0028875839 scopus 로고
    • Catecholamine response to chronic ANG II infusion and its role in myocyte and coronary vascular damage
    • Henegar JR, et al. Catecholamine response to chronic ANG II infusion and its role in myocyte and coronary vascular damage. Am J Physiol. 1995;269(5 Pt 2):H1564-9.
    • (1995) Am J Physiol. , vol.269 , Issue.5 PART 2
    • Henegar, J.R.1
  • 66
    • 0027989853 scopus 로고
    • 1- adrenoceptor-mediated presser responses in the rat
    • DOI 10.1016/0014-2999(94)90309-3
    • Marano G, Argiolas L. Postjunctional regulation by angiotensin II of alpha 1-adrenoceptor-mediated pressor responses in the rat. Eur J Pharmacol. 1994;261(1-2):121-6. (Pubitemid 24263211)
    • (1994) European Journal of Pharmacology , vol.261 , Issue.1-2 , pp. 121-126
    • Marano, G.1    Argiolas, L.2
  • 67
    • 0026495788 scopus 로고
    • Prazosin blunts the antinatriuretic effect of circulating angiotensin II in man
    • Lang CC, et al. Prazosin blunts the antinatriuretic effect of circulating angiotensin II in man. J Hypertens. 1992;10(11):1387-95.
    • (1992) J Hypertens , vol.10 , Issue.11 , pp. 1387-1395
    • Lang, C.C.1
  • 68
    • 0028910026 scopus 로고
    • Angiotensin II induces transcription and expression of alpha 1-adrenergic receptors in vascular smooth muscle cells
    • Hu ZW, et al. Angiotensin II induces transcription and expression of alpha 1-adrenergic receptors in vascular smooth muscle cells. Am J Physiol. 1995;268(3 Pt 2):H1006-14.
    • (1995) Am J Physiol. , vol.268 , Issue.3 PART 2
    • Hu, Z.W.1
  • 69
    • 0037458065 scopus 로고    scopus 로고
    • Vasopressor response to angiotensin II infusion in patients with chronic heart failure receiving β-blockers
    • DOI 10.1161/01.CIR.0000045666.04794.14
    • Vittorio, T.J., et al., Vasopressor response to angiotensin II infusion in patients with chronic heart failure receiving beta-blockers. Circulation, 2003. 107(2): p. 290-3. This study provides clinical evidence for the crosstalk phenomenon between the AT1R and the α-1R in patients with chronic heart failure. (Pubitemid 36135226)
    • (2003) Circulation , vol.107 , Issue.2 , pp. 290-293
    • Vittorio, T.J.1    Lang, C.C.2    Katz, S.D.3    Packer, M.4    Mancini, D.M.5    Jorde, U.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.