HMGB1 gene knockout in mouse embryonic fibroblasts esults in reduced telomerase activity and telomere dysfunction

Chromosoma

Volumn 121, Issue 4, 2012, Pages 419-431

  Polanská, Eva ^b   Dobšáková, Zuzana ^a,b   Dvorácková, Martina ^a   Fajkus, Jirí ^a,b   Štros, Michal ^b  

^a MASARYK UNIVERSITY   (Czech Republic)

^b INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GAMMA H2AX PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B2 PROTEIN; NUCLEAR PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMOSOMAL INSTABILITY; CHROMOSOMAL LOCALIZATION; CHROMOSOME DISORDER; DNA DAMAGE; DNA RECOMBINATION; DNA REPAIR; DNA TRANSFECTION; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; GENE; GENE INACTIVATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE SILENCING; HIGH MOBILITY GROUP B1 GENE; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; TELOMERE; TELOMERE SHORTENING; WILD TYPE;

ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; DNA DAMAGE; DNA FRAGMENTATION; DNA REPLICATION; DOWN-REGULATION; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; HISTONES; HMGB1 PROTEIN; HMGB2 PROTEIN; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICROSCOPY, FLUORESCENCE; RNA; TELOMERASE; TELOMERE;

MAMMALIA;

EID: 84864882450     PISSN: 00095915     EISSN: 14320886     Source Type: Journal    
DOI: 10.1007/s00412-012-0373-x     Document Type: Article

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