Eotaxin in induced sputum of asthmatics: Relationship with eosinophils and eosinophil cationic protein in sputum

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 55, Issue 4, 2000, Pages 392-397

  Yamada, H ^a,b   Yamaguchi, M ^a   Yamamoto, K ^a   Nakajima, T ^a   Hirai, K ^a   Morita, Y ^a   Sano, Y ^b   Hirai, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Doai Memorial Hospital   (Japan)

Author keywords

Bronchial asthma; ELISA; Eosinophil cationic protein; Eosinophils; Eotaxin; Induced sputum

Indexed keywords

CORTICOSTEROID; EOSINOPHIL CATIONIC PROTEIN; EOTAXIN;

ADULT; AGED; ALLERGIC ASTHMA; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHILIA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; SPUTUM ANALYSIS;

ADULT; AGED; ASTHMA; BLOOD PROTEINS; CHEMOKINES, CC; CHEMOTACTIC FACTORS, EOSINOPHIL; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FEMALE; GLUCOCORTICOIDS; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; RIBONUCLEASES; SPUTUM;

EID: 0034032002     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2000.00474.x     Document Type: Article

References (18)

1. 1. GLEICH GJ. The eosinophil and bronchial asthma: current understanding. J Allergy Clin Immunol 1990;85:422-436.
2. 2. PONATH PD, QIN S, RINGLER DJ, et al. Cloning of the human eosinophil chemoattractant, eotaxin expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest 1996;97:604-612.
3. 3. LAMKHIOUED B, RENZI PM, ABI-YOUNES S, et al. Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. J Immunol 1997;159:4593-4601.
4. 4. YING S, ROBINSON DS, MENG Q, et al. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur J Immunol 1997;27:3507-3516.
5. 5. FUKAGAWA K, NAKAJIMA T, TSUBOTA K, SHIMMURA S, SAITO H, HIRAI K. Presence of eotaxin in tears of atopic keratoconjunctivitis patients with severe corneal damage. J Allergy Clin Immunol 1999;103:1220-1221.
6. 6. MORITA A, SHIMOSAKO K, KIKUOKA S, et al. Development of a sensitive enzyme-linked immunosorbent assay for eotaxin and measurement of its levels in human blood. J Immunol Methods 1999;226:159-167.
7. 7. NAKAJIMA T, YAMADA H, IIKURA M, et al. Intracellular localization and release of eotaxin from normal eosinophils. FEBS Lett 1998;434:226-230.
8. 8. Guidelines for the Diagnosis and Management of Asthma. Expert Panel Report II, Bethesda, MD: National Institutes of Health 1997 (NIH publication no. 97-4051).
9. 9. PIN I, GIBSON PG, KOLENDOWICZ R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-29.
10. 10. PIZZICHINI E, PIZZICHINI MMM, EFTHIMIADIS A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 1996;154:308-317.
11. 11. JATAKANON A, LIM S, CHUNG KF, BARNES PJ. An inhaled steroid improves markers of airway inflammation in patients with mild asthma. Eur Respir J 1998;12:1084-1088.
12. 12. YAMADA H, MIYAMASU M, IIKURA M, et al. Eotaxin is a potent chemotaxin for human basophils. Biochem Biophys Res Commun 1997;231:365-368.
13. 13. BAGGIOLINI M. Eotaxin: a VIC (very important chemokine) of allergic inflammation? J Clin Invest 1996;97:587.
14. 14. MOCHIZUKI M, BARTELS J, MALLET AI, CHRISTOPHERS E, SCHRÖDER J-M. IL-4 induces eotaxin: a possible mechanism of selective eosinophil recruitment in helminth infection and atopy. J Immunol 1998;160:60-68.
15. 15. TERAN LM, MOCHIZUKI M, BARTELS J, et al. Th1- and Th2-lype cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. Am J Respir Cell Mol Biol 1999;20:777-786.
16. 16. MIYAMASU M, NAKAJIMA T, MISAKI Y, et al. Dermal fibroblasts represent a potent major source of human eotaxin: in vitro production and cytokine-mediated regulation. Cytokine 1999;11:751-758.
17. 17. MIYAMASU M, YAMAGUCHI M, NAKAJIMA T, et al. T helper 1 (Th1)-derived cytokine interferon-γ is a potent inhibitor of eotaxin synthesis in vitro. Int Immunol 1999;11:1001-1004.
18. 18. KURASHIMA K, MUKAIDA N, FUJIMURA M, SCHRÖDER J-M, MATSUDA T, MATSUSHIMA K. Increase of chemokine levels in sputum precedes exacerbation of acute asthma attacks. J Leukoc Biol 1996;59:313-316.