Contribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice

NeuroReport

Volumn 23, Issue 13, 2012, Pages 780-785

  Ritter, Joseph K ^a   Fang, Youwen ^a   Xia, Min ^a   Li, Pin Lan ^a   Dewey, William L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

acid sphingomyelinase; ceramide; l opioid receptor; morphine tolerance; periaqueductal gray region

Indexed keywords

CERAMIDE; MORPHINE; MORPHINE SULFATE; NALOXONE; SHORT HAIRPIN RNA; SODIUM CHLORIDE; SPHINGOMYELIN PHOSPHODIESTERASE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NOCICEPTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PLACEBO EFFECT; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT RESPONSE;

ANALGESICS, OPIOID; ANIMALS; DRUG TOLERANCE; MALE; MICE; MORPHINE; PAIN; PAIN MANAGEMENT; PAIN MEASUREMENT; PERIAQUEDUCTAL GRAY; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 84864865384     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0b013e3283571757     Document Type: Article

References (17)

1. Yaksh TL. Pharmacology and mechanisms of opioid analgesic activity. Acta Anaesthesiol Scand 1997; 41:94-111. (Pubitemid 27072912)
2. Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 1984; 7:309-338. (Pubitemid 14155301)
3. Bodnar RJ, Williams CL, Lee SJ, Pasternak GW. Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study. Brain Res 1988; 447:25-34.
4. Zhao H, Loh HH, Law PY. Adenylyl cyclase superactivation induced by longterm treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization. Mol Pharmacol 2006; 69:1421-1432
5. . 5 Qiu Y, Wang Y, Law PY, Chen HZ, Loh HH. Cholesterol regulates microopioid receptor-induced beta-arrestin 2 translocation to membrane lipid rafts. Mol Pharmacol 2011; 80:210-218.
6. Gulbins E, Li PL. Physiological and pathophysiological aspects of ceramide. Am J Physiol Regul Integr Comp Physiol 2006; 290:R11-R26.
7. Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, et al. Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. J Pharmacol Exp Ther 2009; 329: 64-75.
8. Coderre TJ, Rollman GB. Naloxone hyperalgesia and stress-induced analgesia in rats. Life Sci 1983; 32:2139-2146. (Pubitemid 13135558)
9. Harris LS, Pierson AK. Some narcotic antagonists in the benzomorphan series. J Pharmacol Exp Ther 1964; 143:141-148.
10. Pedigo NW, Dewey WL, Harris LS. Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. J Pharmacol Exp Ther 1975; 193:845-852.
11. Smith FL, Lohmann AB, Dewey WL. Involvement of phospholipid signal transduction pathways in morphine tolerance in mice. Br J Pharmacol 1999; 128:220-226. (Pubitemid 29425288)
12. Smith FL, Javed R, Elzey MJ, Welch SP, Selley D, Sim-Selley L, et al. Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitors. Brain Res 2002; 958:28-35. (Pubitemid 35441210)
13. Smith FL, Javed RR, Elzey MJ, Dewey WL. The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Res 2003; 985:78-88. (Pubitemid 37272054)
14. Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. Pharmacol Res 2006; 54:474-480. (Pubitemid 46053824)
15. Benarroch EE. Basic neurosciences with clinical applications. Philadelphia, PA: Elsevier Health Sciences; 2006.
16. Bryant L, Doyle T, Chen Z, Cuzzocrea S, Masini E, Vinci MC, et al. Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance. Neurosci Lett 2009; 463:49-53.
17. Muscoli C, Doyle T, Dagostino C, Bryant L, Chen Z, Watkins LR, et al. Counter-regulation of opioid analgesia by glial-derived bioactive sphingolipids. J Neurosci 2010; 30:15400-15408.