Characterization of in vitro metabolites of trimethoprim and diaveridine in pig liver microsomes by liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry

Biomedical Chromatography

Volumn 26, Issue 9, 2012, Pages 1101-1108

  Liu, Zhao Ying ^a   Wu, Yong ^a   Sun, Zhi Liang ^a   Wan, Leren ^b  

^a HUNAN AGRICULTURAL UNIVERSITY   (China)

^b Limited ^*  (China)

Author keywords

Diaveridine; Hybrid ion trap time of flight mass spectrometry; Metabolism; Pig liver microsomes; Trimethoprim

Indexed keywords

BIOMOLECULES; CARBON; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; IONS; MAMMALS; MASS SPECTROMETRY; METABOLITES; PHYSIOLOGY; SULFUR COMPOUNDS;

DIAVERIDINE; HYBRID ION TRAP/TIME-OF-FLIGHT MASS SPECTROMETRY; ION TRAPS; LIVER MICROSOMES; O-DEMETHYLATION; PIG LIVER; PIG LIVER MICROSOME; TIME OF FLIGHT MASS SPECTROMETRY; TRAP TIME; TRIMETHOPRIM;

METABOLISM;

DIAVERIDINE; DRUG METABOLITE; TRIMETHOPRIM;

ACCURACY; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG DETERMINATION; DRUG HYDROXYLATION; DRUG STRUCTURE; DRUG TRANSFORMATION; EXPERIMENTAL PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; LIVER MICROSOME; MALE; NONHUMAN; TIME OF FLIGHT MASS SPECTROMETRY;

ANIMALIA; SUIDAE;

EID: 84864825929     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1754     Document Type: Article

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