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Volumn 83, Issue 9, 2012, Pages 935-940

Antibodies against the main immunogenic region of the acetylcholine receptor correlate with disease severity in myasthenia gravis

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; MAIN IMMUNOGENIC REGION AUTOANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 35; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84864819393     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2012-302705     Document Type: Article
Times cited : (51)

References (39)
  • 1
    • 0035105784 scopus 로고    scopus 로고
    • Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
    • DOI 10.1038/85520
    • Hoch W, McConville J, Helms S, et al. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med 2001;7:365-8. (Pubitemid 32224355)
    • (2001) Nature Medicine , vol.7 , Issue.3 , pp. 365-368
    • Hoch, W.1    Mcconville, J.2    Helms, S.3    Newsom-Davis, J.4    Melms, A.5    Vincent, A.6
  • 2
    • 79952513213 scopus 로고    scopus 로고
    • Autoantibodies to LDL receptor-related protein 4 in myasthenia gravis
    • Higuchi O, Hamuro J, Motomura M, et al. Autoantibodies to LDL receptor-related protein 4 in myasthenia gravis. Ann Neurol 2011;69:418-22.
    • (2011) Ann Neurol , vol.69 , pp. 418-422
    • Higuchi, O.1    Hamuro, J.2    Motomura, M.3
  • 3
    • 84859939384 scopus 로고    scopus 로고
    • Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis
    • Zhang B, Tzartos JS, Belimezi M, et al. Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis. Arch Neurol 2012;69:445-51.
    • (2012) Arch Neurol , vol.69 , pp. 445-451
    • Zhang, B.1    Tzartos, J.S.2    Belimezi, M.3
  • 4
    • 77950462859 scopus 로고    scopus 로고
    • To build a synapse: Signaling pathways in neuromuscular junction assembly
    • Wu H, Xiong WC, Mei L. To build a synapse: signaling pathways in neuromuscular junction assembly. Development 2010;137:1017-33.
    • (2010) Development , vol.137 , pp. 1017-1033
    • Wu, H.1    Xiong, W.C.2    Mei, L.3
  • 5
    • 84856491042 scopus 로고    scopus 로고
    • The pathophysiology and treatment of autoimmune neuromuscular junction diseases
    • Motomura M. The pathophysiology and treatment of autoimmune neuromuscular junction diseases. Rinsho Shinkeigaku 2011; 51:872-6.
    • (2011) Rinsho Shinkeigaku , vol.51 , pp. 872-876
    • Motomura, M.1
  • 6
    • 0022373590 scopus 로고
    • Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: Results in 153 validated cases and 2967 diagnostic assays
    • Vincent A, Newsom-Davis J. Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays. J Neurol Neurosurg Psychiatry 1985;48:1246-52. (Pubitemid 16229407)
    • (1985) Journal of Neurology Neurosurgery and Psychiatry , vol.48 , Issue.12 , pp. 1246-1252
    • Vincent, A.1    Newsom-Davis, J.2
  • 7
    • 0027213427 scopus 로고
    • Clinical implementation of anti-acetylcholine receptor antibodies
    • Somnier FE. Clinical implementation of anti-acetylcholine receptor antibodies. J Neurol Neurosurg Psychiatry 1993;56:496-504. (Pubitemid 23171780)
    • (1993) Journal of Neurology Neurosurgery and Psychiatry , vol.56 , Issue.5 , pp. 496-504
    • Somnier, F.E.1
  • 8
    • 0019465531 scopus 로고
    • Humoral immunity in myasthenia gravis: Biochemical characterization of acquired antireceptor antibodies and clinical correlations
    • DOI 10.1002/ana.410100506
    • Tindall RS. Humoral immunity in myasthenia gravis: biochemical characterization of acquired antireceptor antibodies and clinical correlations. Ann Neurol 1981;10:437-47. (Pubitemid 11029783)
    • (1981) Annals of Neurology , vol.10 , Issue.5 , pp. 437-447
    • Tindall, R.S.A.1
  • 10
    • 0020513595 scopus 로고
    • Myasthenia gravis: Long-term correlation of binding and bungarotoxin blocking antibodies against acetylcholine receptors with changes in disease severity
    • Besinger UA, Toyka KV, Hömberg M, et al. Myasthenia gravis: long-term correlation of binding and bungarotoxin blocking antibodies against acetylcholine receptors with changes in disease severity. Neurology 1983;33:1316-21. (Pubitemid 13021194)
    • (1983) Neurology , vol.33 , Issue.10 , pp. 1316-1321
    • Besinger, U.A.1    Toyka, K.V.2    Homberg, M.3
  • 11
    • 0023625297 scopus 로고
    • Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis
    • Howard FM Jr, Lennon VA, Finley J, et al. Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis. Ann N Y Acad Sci 1987;505:526-38.
    • (1987) Ann N Y Acad Sci , vol.505 , pp. 526-538
    • Howard Jr., F.M.1    Lennon, V.A.2    Finley, J.3
  • 12
    • 0024416011 scopus 로고
    • Anti-acetylcholine receptor antibodies block bungarotoxin binding to native human acetylcholine receptor on the surface of TE671 cells
    • Pachner AR. Anti-acetylcholine receptor antibodies block bungarotoxin binding to native human acetylcholine receptor on the surface of TE671 cells. Neurology 1989;39:1057-61. (Pubitemid 19217473)
    • (1989) Neurology , vol.39 , Issue.8 , pp. 1057-1061
    • Pachner, A.R.1
  • 13
    • 33747035017 scopus 로고    scopus 로고
    • Anti-MuSK antibodies: Correlation with myasthenia gravis severity
    • DOI 10.1212/01.wnl.0000228225.23349.5d, PII 0000611420060808000035
    • Bartoccioni E, Scuderi F, Minicuci GM, et al. Anti-MuSK antibodies: correlation with myasthenia gravis severity. Neurology 2006;67:505-7. (Pubitemid 44214984)
    • (2006) Neurology , vol.67 , Issue.3 , pp. 505-507
    • Bartoccioni, E.1    Scuderi, F.2    Minicuci, G.M.3    Marino, M.4    Ciaraffa, F.5    Evoli, A.6
  • 15
    • 79959324658 scopus 로고    scopus 로고
    • Anti-MuSK antibody myasthenia gravis: Clinical findings and response to treatment in two large cohorts
    • Guptill JT, Sanders DB, Evoli A. Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts. Muscle Nerve 2011;44:36-40.
    • (2011) Muscle Nerve , vol.44 , pp. 36-40
    • Guptill, J.T.1    Sanders, D.B.2    Evoli, A.3
  • 16
    • 33645521800 scopus 로고    scopus 로고
    • Induction of myasthenia by immunization against muscle-specific kinase
    • Shigemoto K, Kubo S, Maruyama N, et al. Induction of myasthenia by immunization against muscle-specific kinase. J Clin Invest 2006;116 :1016-24.
    • (2006) J Clin Invest , vol.116 , pp. 1016-1024
    • Shigemoto, K.1    Kubo, S.2    Maruyama, N.3
  • 17
    • 79958743273 scopus 로고    scopus 로고
    • Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice
    • Punga AR, Lin S, Oliveri F, et al. Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice. Exp Neurol 2011; 230:207-17.
    • (2011) Exp Neurol , vol.230 , pp. 207-217
    • Punga, A.R.1    Lin, S.2    Oliveri, F.3
  • 18
    • 0345436983 scopus 로고
    • Monoclonal antibodies used to probe acetylcholine receptor structure: Localization of the main immunogenic region and detection of similarities between subunits
    • Tzartos SJ, Lindstrom JM. Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits. Proc Natl Acad Sci U S A 1980;77:755-9. (Pubitemid 10108379)
    • (1980) Proceedings of the National Academy of Sciences of the United States of America , vol.77 , Issue.2 II , pp. 755-759
    • Tzartos, S.J.1    Lindstrom, J.M.2
  • 19
    • 0023220157 scopus 로고
    • Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor
    • DOI 10.1016/0165-5728(87)90092-0
    • Tzartos S, Hochschwender S, Vasquez P, et al. Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor. J Neuroimmunol 1987;15:185-94. (Pubitemid 17075151)
    • (1987) Journal of Neuroimmunology , vol.15 , Issue.2 , pp. 185-194
    • Tzartos, S.1    Hochschwender, S.2    Vasquez, P.3    Lindstrom, J.4
  • 20
    • 0029143458 scopus 로고
    • Three-dimensional location of the main immunogenic region of the acetylcholine receptor
    • Beroukhim R, Unwin N. Three-dimensional location of the main immunogenic region of the acetylcholine receptor. Neuron 1995;15 :323-31.
    • (1995) Neuron , vol.15 , pp. 323-331
    • Beroukhim, R.1    Unwin, N.2
  • 22
    • 75049083167 scopus 로고    scopus 로고
    • Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region
    • Luo J, Lindstrom J. Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region. J Mol Neurosci 2010;40:217-20.
    • (2010) J Mol Neurosci , vol.40 , pp. 217-220
    • Luo, J.1    Lindstrom, J.2
  • 24
    • 0034075943 scopus 로고    scopus 로고
    • Treatment of passively transferred experimental autoimmune myasthenia gravis using papain
    • DOI 10.1046/j.1365-2249.2000.01202.x
    • Poulas K, Tsouloufis T, Tzartos SJ. Treatment of passively transferred experimental autoimmune myasthenia gravis using papain. Clin Exp Immunol 2000;120:363-8. (Pubitemid 30304235)
    • (2000) Clinical and Experimental Immunology , vol.120 , Issue.2 , pp. 363-368
    • Poulas, K.1    Tsouloufis, T.2    Tzartos, S.J.3
  • 25
    • 0344143422 scopus 로고
    • Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies
    • Lennon VA, McCormick DJ, Lambert EH, et al. Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies. Proc Natl Acad Sci U S A 1985;82:8805-9. (Pubitemid 16101133)
    • (1985) Proceedings of the National Academy of Sciences of the United States of America , vol.82 , Issue.24 , pp. 8805-8809
    • Lennon, V.A.1    McCormick, D.J.2    Lambert, E.H.3
  • 26
    • 0023756770 scopus 로고
    • Anti-acetylcholine receptor antibody specificities in serum and in thymic cell culture supernatants from myasthenia gravis patients
    • Heidenreich F, Vincent A, Willcox N, et al. Anti-acetylcholine receptor antibody specificities in serum and in thymic cell culture supernatants from myasthenia gravis patients. Neurology 1988; 38:1784-8. (Pubitemid 18265048)
    • (1988) Neurology , vol.38 , Issue.11 , pp. 1784-1788
    • Heidenreich, F.1    Vincent, A.2    Willcox, N.3    Newsom-Davis, J.4
  • 27
    • 0035902009 scopus 로고    scopus 로고
    • Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
    • DOI 10.1038/35077011
    • Brejc K, van Dijk WJ, Klaassen RV, et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 2001;411:269-76. (Pubitemid 32467026)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 269-276
    • Brejc, K.1    Van Dijk, W.J.2    Klaassen, R.V.3    Schuurmans, M.4    Van Der, O.J.5    Smit, A.B.6    Sixma, T.K.7
  • 28
    • 0141748121 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors of muscles and nerves: Comparison of their structures, functional roles, and vulnerability to pathology
    • DOI 10.1196/annals.1254.007
    • Lindstrom JM. Nicotinic acetylcholine receptors of muscles and nerves: comparison of their structures, functional roles, and vulnerability to pathology. Ann N Y Acad Sci 2003;998:41-52. (Pubitemid 37194146)
    • (2003) Annals of the New York Academy of Sciences , vol.998 , pp. 41-52
    • Lindstrom, J.M.1
  • 29
    • 70449348367 scopus 로고    scopus 로고
    • Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity
    • Luo J, Taylor P, Losen M, et al. Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. J Neurosci 2009;29:13898-908.
    • (2009) J Neurosci , vol.29 , pp. 13898-13908
    • Luo, J.1    Taylor, P.2    Losen, M.3
  • 30
    • 33748976752 scopus 로고    scopus 로고
    • Ocular myasthenia: Diagnosis, treatment, and pathogenesis
    • DOI 10.1097/01.nrl.0000240856.03505.b5, PII 0012789320060900000001
    • Kusner LL, Puwanant A, Kaminski HJ. Ocular myasthenia: diagnosis, treatment, and pathogenesis. Neurologist 2006;12 :231-9. (Pubitemid 44440016)
    • (2006) Neurologist , vol.12 , Issue.5 , pp. 231-239
    • Kusner, L.L.1    Puwanant, A.2    Kaminski, H.J.3
  • 32
  • 33
    • 0019323814 scopus 로고
    • Intercostal muscle acetylcholine receptors in longstanding ocular myasthenia
    • Lecky BR, Morgan-Hughes JA, Landon DN, et al. Intercostal muscle acetylcholine receptors in longstanding ocular myasthenia. Lancet 1980;2 :1311-12.
    • (1980) Lancet , vol.2 , pp. 1311-1312
    • Lecky, B.R.1    Morgan-Hughes, J.A.2    Landon, D.N.3
  • 34
    • 0024457007 scopus 로고
    • Diagnostic significance of IgG, C3, and C9 at the limb muscle motor end-plate in minimal myasthenia gravis
    • Tsujihata M, Yoshimura T, Satoh A, et al. Diagnostic significance of IgG, C3, and C9 at the limb muscle motor end-plate in minimal myasthenia gravis. Neurology 1989;39:1359-63. (Pubitemid 19246812)
    • (1989) Neurology , vol.39 , Issue.10 , pp. 1359-1363
    • Tsujihata, M.1    Yoshimura, T.2    Satoh, A.3    Kinoshita, I.4    Matsuo, H.5    Mori, M.6    Nagataki, S.7
  • 36
    • 0027319945 scopus 로고
    • Differences in acetylcholine receptor-antibody interactions between extraocular and extremity muscle fibers
    • Oda K. Differences in acetylcholine receptor-antibody interactions between extraocular and extremity muscle fibers. Ann N Y Acad Sci 1993;681:238-55. (Pubitemid 23233826)
    • (1993) Annals of the New York Academy of Sciences , vol.681 , pp. 238-255
    • Oda, K.1
  • 37
    • 4544278812 scopus 로고    scopus 로고
    • Complement regulators in extraocular muscle and experimental autoimmune myasthenia gravis
    • DOI 10.1016/j.expneurol.2004.06.005, PII S0014488604002328
    • Kaminski HJ, Li Z, Richmonds C, et al. Complement regulators in extraocular muscle and experimental autoimmune myasthenia gravis. Exp Neurol 2004;189:333-42. (Pubitemid 39221825)
    • (2004) Experimental Neurology , vol.189 , Issue.2 , pp. 333-342
    • Kaminski, H.J.1    Li, Z.2    Richmonds, C.3    Lin, F.4    Medof, M.E.5
  • 38
    • 0018340751 scopus 로고
    • Limb muscle endplates in ocular myasthenia gravis: Quantitative ultrastructural study
    • Tsujihata M, Hazama R, Ishii N, et al. Limb muscle endplates in ocular myasthenia gravis: quantitative ultrastructural study. Neurology 1979;29:654-61. (Pubitemid 9135466)
    • (1979) Neurology , vol.29 , Issue.5 , pp. 654-661
    • Tsujihata, M.1    Hazama, R.2    Ishii, N.3
  • 39
    • 45249090856 scopus 로고    scopus 로고
    • Extraocular muscle susceptibility to myasthenia gravis: Unique immunological environment?
    • DOI 10.1196/annals.1405.037, Myasthenia Gravis and Related Disorders 11th International Conference
    • Soltys J, Gong B, Kaminski HJ, et al. Extraocular muscle susceptibility to myasthenia gravis: unique immunological environment? Ann N Y Acad Sci 2008;1132:220-4. (Pubitemid 351841377)
    • (2008) Annals of the New York Academy of Sciences , vol.1132 , pp. 220-224
    • Soltys, J.1    Gong, B.2    Kaminski, H.J.3    Zhou, Y.4    Kusner, L.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.