Main immunogenic region structure promotes binding of conformation- dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity

Journal of Neuroscience

Volumn 29, Issue 44, 2009, Pages 13898-13908

  Luo, Jie ^a   Taylor, Palmer ^b   Losen, Mario ^c   De Baets, Marc H ^c   Shelton, G Diane ^d   Lindstrom, Jon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b San Diego   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; AUTOANTIBODY; CHOLINERGIC RECEPTOR; MONOCLONAL ANTIBODY; NICOTINIC RECEPTOR;

APLYSIA; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; MAJOR CLINICAL STUDY; MYASTHENIA GRAVIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

AMINO ACID SEQUENCE; ANIMALS; APLYSIA; AUTOANTIBODIES; AUTOANTIGENS; BINDING SITES, ANTIBODY; BINDING, COMPETITIVE; CATS; CATTLE; CELL LINE; DOGS; EPITOPES; FEMALE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MYASTHENIA GRAVIS; NICOTINIC AGONISTS; PROTEIN CONFORMATION; RATS; RECEPTORS, NICOTINIC; XENOPUS;

EID: 70449348367     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2833-09.2009     Document Type: Article

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