메뉴 건너뛰기




Volumn 424, Issue 3, 2012, Pages 620-623

Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation

Author keywords

arrestin2; C Myc; Endoglin; ERK; Smads; TGF

Indexed keywords

BETA ARRESTIN 2; CYCLIN D1; ENDOGLIN; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84864781306     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.163     Document Type: Article
Times cited : (24)

References (22)
  • 1
    • 33144462810 scopus 로고    scopus 로고
    • Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease
    • Abdalla S.A., Letarte M. Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease. J. Med. Genet. 2006, 43(2):97-110.
    • (2006) J. Med. Genet. , vol.43 , Issue.2 , pp. 97-110
    • Abdalla, S.A.1    Letarte, M.2
  • 2
    • 77956187467 scopus 로고    scopus 로고
    • Signaling by members of the TGF-β family in vascular morphogenesis and disease
    • Pardali E., Goumans M.J., ten Dijke P. Signaling by members of the TGF-β family in vascular morphogenesis and disease. Trends Cell Biol. 2010, 20:556-567.
    • (2010) Trends Cell Biol. , vol.20 , pp. 556-567
    • Pardali, E.1    Goumans, M.J.2    ten Dijke, P.3
  • 4
    • 34547221505 scopus 로고    scopus 로고
    • Understanding the biology of angiogenesis: review of the most important molecular mechanisms
    • Otrock Z.K., Mahfouz R.A., Makarem J.A., Shamseddine A.I. Understanding the biology of angiogenesis: review of the most important molecular mechanisms. Blood Cells Mol. Dis. 2007, 39(2):212-220.
    • (2007) Blood Cells Mol. Dis. , vol.39 , Issue.2 , pp. 212-220
    • Otrock, Z.K.1    Mahfouz, R.A.2    Makarem, J.A.3    Shamseddine, A.I.4
  • 7
    • 36849054447 scopus 로고    scopus 로고
    • Novel biochemical pathways of endoglin in vascular cell physiology
    • Bernabeu C., Conley B.A. Novel biochemical pathways of endoglin in vascular cell physiology. J. Cell. Biochem. 2007, 102:1375-1388.
    • (2007) J. Cell. Biochem. , vol.102 , pp. 1375-1388
    • Bernabeu, C.1    Conley, B.A.2
  • 8
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R., Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003, 425:577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 9
    • 0037047426 scopus 로고    scopus 로고
    • Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor- receptors I and II
    • Guerrero-Esteo M., Sanchez-Elsner T., Letamendia A., Bernabeu C. Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor- receptors I and II. J. Biol. Chem. 2002, 277(32):29197-29209.
    • (2002) J. Biol. Chem. , vol.277 , Issue.32 , pp. 29197-29209
    • Guerrero-Esteo, M.1    Sanchez-Elsner, T.2    Letamendia, A.3    Bernabeu, C.4
  • 10
    • 3042589327 scopus 로고    scopus 로고
    • Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain
    • Conley B.A., Koleva R., Smith J.D., Kacer D., Zhang D., Bernabéu C., Vary C.P. Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. J. Biol. Chem. 2004, 279(26):27440-27449.
    • (2004) J. Biol. Chem. , vol.279 , Issue.26 , pp. 27440-27449
    • Conley, B.A.1    Koleva, R.2    Smith, J.D.3    Kacer, D.4    Zhang, D.5    Bernabéu, C.6    Vary, C.P.7
  • 11
    • 3543041235 scopus 로고    scopus 로고
    • Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins
    • Sanz-Rodriguez F., Guerrero-Esteo M., Botella L.M., Banville D., Vary C.P., Bernabéu C. Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. J. Biol. Chem. 2004, 279(31):32858-32868.
    • (2004) J. Biol. Chem. , vol.279 , Issue.31 , pp. 32858-32868
    • Sanz-Rodriguez, F.1    Guerrero-Esteo, M.2    Botella, L.M.3    Banville, D.4    Vary, C.P.5    Bernabéu, C.6
  • 12
    • 34547111838 scopus 로고    scopus 로고
    • The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells
    • Lee N.Y., Blobe G.C. The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells. J. Biol. Chem. 2007, 282(29):21507-21517.
    • (2007) J. Biol. Chem. , vol.282 , Issue.29 , pp. 21507-21517
    • Lee, N.Y.1    Blobe, G.C.2
  • 13
    • 57749084578 scopus 로고    scopus 로고
    • Endoglin promotes transforming growth factor β-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC
    • Lee N.Y., Ray B., How T., Blobe G.C. Endoglin promotes transforming growth factor β-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC. J. Biol. Chem. 2008, 283(47):32527-32533.
    • (2008) J. Biol. Chem. , vol.283 , Issue.47 , pp. 32527-32533
    • Lee, N.Y.1    Ray, B.2    How, T.3    Blobe, G.C.4
  • 14
    • 38349173601 scopus 로고    scopus 로고
    • ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2
    • Park S.O., Lee Y.J. ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood 2008, 111:633-642.
    • (2008) Blood , vol.111 , pp. 633-642
    • Park, S.O.1    Lee, Y.J.2
  • 15
    • 23044437149 scopus 로고    scopus 로고
    • Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta 1 with higher affinity receptors and an activated ALK1 pathway
    • Pece-Barbara N., et al. Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta 1 with higher affinity receptors and an activated ALK1 pathway. J. Biol. Chem. 2005, 280(30):27800-27808.
    • (2005) J. Biol. Chem. , vol.280 , Issue.30 , pp. 27800-27808
    • Pece-Barbara, N.1
  • 17
    • 33748749625 scopus 로고    scopus 로고
    • Endoglin structure and function determinants of endoglin phosphorylation by transforming growth factor-β receptors
    • Koleva R.I., Conley B.A., Romero D., Riley K.S., Marto J.A., Lux A., Vary C.P. Endoglin structure and function determinants of endoglin phosphorylation by transforming growth factor-β receptors. J. Biol. Chem. 2006, 19(281):25110-25123.
    • (2006) J. Biol. Chem. , vol.19 , Issue.281 , pp. 25110-25123
    • Koleva, R.I.1    Conley, B.A.2    Romero, D.3    Riley, K.S.4    Marto, J.A.5    Lux, A.6    Vary, C.P.7
  • 18
    • 0242708765 scopus 로고    scopus 로고
    • Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels
    • Fonsatti E., et al. Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels. Oncogene 2003, 22(42):6557-6563.
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6557-6563
    • Fonsatti, E.1
  • 19
    • 33744985816 scopus 로고    scopus 로고
    • Soluble endoglin contributes to the pathogenesis of preeclampsia
    • Venkatesha S., et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat. Med. 2006, 12:642-649.
    • (2006) Nat. Med. , vol.12 , pp. 642-649
    • Venkatesha, S.1
  • 20
    • 0036829567 scopus 로고    scopus 로고
    • Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase
    • Funaba M., Zimmerman C.M., Mathews L.S. Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase. J. Biol. Chem. 2002, 277(44):41361-41368.
    • (2002) J. Biol. Chem. , vol.277 , Issue.44 , pp. 41361-41368
    • Funaba, M.1    Zimmerman, C.M.2    Mathews, L.S.3
  • 21
    • 0347991862 scopus 로고    scopus 로고
    • Integration of Smad and MAPK pathways: a link and linker revisited
    • Massague J. Integration of Smad and MAPK pathways: a link and linker revisited. Genes Dev. 2003, 17:2993-2997.
    • (2003) Genes Dev. , vol.17 , pp. 2993-2997
    • Massague, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.