Base excision repair gene polymorphisms are associated with inflammation in patients undergoing chronic hemodialysis

Biochemical and Biophysical Research Communications

Volumn 424, Issue 3, 2012, Pages 611-615

  Cai, Zhenming ^a,b   Guo, Wenwen ^a,b   Chen, Huimei ^a,b   Tao, Jing ^c   Cao, Lili ^a,b   Sun, Wei ^c   Wang, Yaping ^a,b  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

BER gene; Hemodialysis patients; IL 1 ; IL 6; Inflammation; Polymorphism

Indexed keywords

HOGG1 PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RELEASE; DNA DAMAGE; EXCISION REPAIR; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADULT; AGED; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MIDDLE AGED; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; RENAL DIALYSIS;

EID: 84864762702     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.161     Document Type: Article

References (33)

1. Coskun C., Kural A., Doventas Y., Koldas M., Ozturk H., Inal B.B., Gumus A. Hemodialysis and protein oxidation products. Ann. NY Acad. Sci. 2007, 1100:404-408.
2. Rysz J., Banach M., Cialkowska-Rysz A., Stolarek R., Barylski M., Drozdz J., Okonski P. Blood serum levels of IL-2, IL-6, IL-8, TNF-alpha and IL-1beta in patients on maintenance hemodialysis. Cell. Mol. Immunol. 2006, 3:151-154.
3. Stenvinkel P. Inflammation in end-stage renal failure: could it be treated?. Nephrol. Dial. Transplant. 2002, 17(Suppl. 8):33-38.
4. Zoccali C., Tripepi G., Mallamaci F. Dissecting inflammation in ESRD: do cytokines and C-reactive protein have a complementary prognostic value for mortality in dialysis patients?. J. Am. Soc. Nephrol. 2006, 17:S169-173.
5. Barreto D.V., Barreto F.C., Liabeuf S., Temmar M., Lemke H.D., Tribouilloy C., Choukroun G., Vanholder R., Massy Z.A. Plasma interleukin-6 is independently associated with mortality in both hemodialysis and pre-dialysis patients with chronic kidney disease. Kidney Int. 2010, 77:550-556.
6. Bologa R.M., Levine D.M., Parker T.S., Cheigh J.S., Serur D., Stenzel K.H., Rubin A.L. Interleukin-6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients. Am. J. Kidney Dis. 1998, 32:107-114.
7. Pecoits-Filho R., Barany P., Lindholm B., Heimburger O., Stenvinkel P. Interleukin-6 is an independent predictor of mortality in patients starting dialysis treatment. Nephrol. Dial. Transplant. 2002, 17:1684-1688.
8. Hung C.Y., Chen Y.A., Chou C.C., Yang C.S. Nutritional and inflammatory markers in the prediction of mortality in Chinese hemodialysis patients. Nephron Clin. Pract. 2005, 100:c20-26.
9. Kumagai S., Jikimoto T., Saegusa J. Pathological roles of oxidative stress in autoimmune diseases. Rinsho Byori 2003, 51:126-132.
10. Reuter S., Gupta S.C., Chaturvedi M.M., Aggarwal B.B. Oxidative stress, inflammation, and cancer: how are they linked?. Free Radic. Biol. Med. 2010, 49:1603-1616.
11. Taha R., Seidman E., Mailhot G., Boudreau F., Gendron F.P., Beaulieu J.F., Menard D., Delvin E., Amre D., Levy E. Oxidative stress and mitochondrial functions in the intestinal Caco-2/15 cell line. PLoS One 2010, 5:e11817.
12. Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993, 362:709-715.
13. Trabulus S., Guven G.S., Altiparmak M.R., Batar B., Tun O., Yalin A.S., Tunckale A., Guven M. DNA repair XRCC1 Arg399Gln polymorphism is associated with the risk of development of end-stage renal disease. Mol. Biol. Rep. 2012, 39:6995-7001.
14. De Bont R., van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 2004, 19:169-185.
15. Robertson A.B., Klungland A., Rognes T., Leiros I. DNA repair in mammalian cells: Base excision repair: the long and short of it. Cell. Mol. Life Sci. 2009, 66:981-993.
16. Yamane A., Shinmura K., Sunaga N., Saitoh T., Yamaguchi S., Shinmura Y., Yoshimura K., Murakami H., Nojima Y., Kohno T., Yokota J. Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo. Carcinogenesis 2003, 24:1031-1037.
17. Locatelli F., Canaud B., Eckardt K.U., Stenvinkel P., Wanner C., Zoccali C. Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol. Dial. Transplant. 2003, 18:1272-1280.
18. Goode E.L., Ulrich C.M., Potter J.D. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomarkers Prev. 2002, 11:1513-1530.
19. Sun C., Chen H., Guo W., Zhang K., Qi Q., Gu X., Zhu D., Wang Y. A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases. Free Radic. Biol. Med. 2010, 48:430-436.
20. Cai Z., Chen H., Tao J., Guo W., Liu X., Zheng B., Sun W., Wang Y. Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population. Oxid. Med. Cell Longev. 2012, 2012:928421.
21. Punal J., Lema L.V., Sanhez-Guisande D., Ruano-Ravina A. Clinical effectiveness and quality of life of conventional haemodialysis versus short daily haemodialysis: a systematic review. Nephrol. Dial. Transplant. 2008, 23:2634-2646.
22. Zuo L., Wang M. Current burden and probable increasing incidence of ESRD in China. Clin. Nephrol. 2010, 74(Suppl. 1):S20-22.
23. Brymora A., Flisinski M., Grzesk G., Szadujkis-Szadurski L., Odrowaz-Sypniewska G., Manitius J. Inflammation, malnutrition and vascular contraction in experimental chronic kidney disease. J. Nephrol. 2007, 20:423-429.
24. Cheung W.W., Paik K.H., Mak R.H. Inflammation and cachexia in chronic kidney disease. Pediatr. Nephrol. 2010, 25:711-724.
25. Eleftheriadis T., Kartsios C., Yiannaki E., Kazila P., Antoniadi G., Liakopoulos V., Markala D. Chronic inflammation and T cell zeta-chain downregulation in hemodialysis patients. Am. J. Nephrol. 2008, 28:152-157.
26. Filiopoulos V., Hadjiyannakos D., Metaxaki P., Sideris V., Takouli L., Anogiati A., Vlassopoulos D. Inflammation and oxidative stress in patients on hemodiafiltration. Am. J. Nephrol. 2008, 28:949-957.
27. Descamps-Latscha B., Drueke T., Witko-Sarsat V. Dialysis-induced oxidative stress: biological aspects, clinical consequences, and therapy. Semin. Dial. 2001, 14:193-199.
28. Sedelnikova O.A., Redon C.E., Dickey J.S., Nakamura A.J., Georgakilas A.G., Bonner W.M. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat. Res. 2010, 704:152-159.
29. Hakem R. DNA-damage repair; the good, the bad, and the ugly. EMBO J. 2008, 27:589-605.
30. Maynard S., Schurman S.H., Harboe C., de Souza-Pinto N.C., Bohr V.A. Base excision repair of oxidative DNA damage and association with cancer and aging. Carcinogenesis 2009, 30:2-10.
31. Hung R.J., Hall J., Brennan P., Boffetta P. Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review. Am. J. Epidemiol. 2005, 162:925-942.
32. Svilar D., Goellner E.M., Almeida K.H., Sobol R.W. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid. Redox Signal. 2011, 14:2491-2507.
33. Xie Y., Yang H., Miller J.H., Shih D.M., Hicks G.G., Xie J., Shiu R.P. Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis 2008, 29:722-728.