A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies

Atherosclerosis

Volumn 223, Issue 2, 2012, Pages 421-426

  Brautbar, Ariel ^a,b,c   Pompeii, Lisa A ^d   Dehghan, Abbas ^e,f   Ngwa, Julius S ^g   Nambi, Vijay ^b,c   Virani, Salim S ^b,c,h   Rivadeneira, Fernando ^e,f   Uitterlinden, André G ^e,f   Hofman, Albert ^e,f   Witteman, Jacqueline C M ^e,f   Pencina, Michael J ^g   Folsom, Aaron R ⁱ   Cupples, L Adrienne ^g,j   Ballantyne, Christie M ^b,c   Boerwinkle, Eric ^d,k  

^a MARSHFIELD CLINIC   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f Netherlands Consortium for Healthy Ageing   (Netherlands)

^g BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^h MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF MINNESOTA   (United States)

^j FRAMINGHAM HEART STUDY   (United States)

^k UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

more..

Author keywords

Coronary disease; Genetics; Risk factors

Indexed keywords

ADULT; ARTICLE; ATHEROSCLEROSIS; CALIBRATION; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; FRAMINGHAM RISK SCORE; GENETIC RISK; HAZARD RATIO; HISPANIC; HUMAN; ISCHEMIC HEART DISEASE; LITERATURE; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; PROGENY; PROPORTIONAL HAZARDS MODEL; RECEIVER OPERATING CHARACTERISTIC; SINGLE NUCLEOTIDE POLYMORPHISM;

AREA UNDER CURVE; CORONARY DISEASE; DISCRIMINANT ANALYSIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MODELS, GENETIC; MULTIVARIATE ANALYSIS; NETHERLANDS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; ROC CURVE; UNITED STATES;

EID: 84864762687     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.05.035     Document Type: Article

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