메뉴 건너뛰기




Volumn 21, Issue 12, 2012, Pages 2170-2178

Additive effects of sonic hedgehog and nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CYTOKINE; PROTEIN NELL1; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

EID: 84864710380     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0461     Document Type: Article
Times cited : (77)

References (51)
  • 1
    • 2142808834 scopus 로고    scopus 로고
    • Fat's loss is bone's gain
    • Pei L and P Tontonoz. (2004). Fat's loss is bone's gain. J Clin Invest 113:805-806.
    • (2004) J Clin Invest , vol.113 , pp. 805-806
    • Pei, L.1    Tontonoz, P.2
  • 4
    • 4243137398 scopus 로고    scopus 로고
    • Bone and fat: Old ques-tions, new insights
    • Gimble JM and ME Nuttall. (2004). Bone and fat: old ques-tions, new insights Endocrine 23:183-188.
    • (2004) Endocrine , vol.23 , pp. 183-188
    • Gimble, J.M.1    Nuttall, M.E.2
  • 5
    • 35048898435 scopus 로고    scopus 로고
    • BMP7 promotes adipogenic but not osteo-/chondrogenic differentiation of adult human bone marrow-derived stem cells in high-density micro-mass culture
    • Neumann K, M Endres, J Ringe, B Flath, R Manz, T Haupl, M Sittinger and C Kaps. (2007). BMP7 promotes adipogenic but not osteo-/chondrogenic differentiation of adult human bone marrow-derived stem cells in high-density micro-mass culture. J Cell Biochem 102:626-637.
    • (2007) J Cell Biochem , vol.102 , pp. 626-637
    • Neumann, K.1    Endres, M.2    Ringe, J.3    Flath, B.4    Manz, R.5    Haupl, T.6    Sittinger, M.7    Kaps, C.8
  • 6
    • 0034705835 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesen-chymal precursor cells in synergy with BRL 49653 (rosigli-tazone)
    • Sottile V and K Seuwen. (2000). Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesen-chymal precursor cells in synergy with BRL 49653 (rosigli-tazone). FEBS Lett 475:201-204.
    • (2000) FEBS Lett , vol.475 , pp. 201-204
    • Sottile, V.1    Seuwen, K.2
  • 7
    • 77954657973 scopus 로고    scopus 로고
    • Regulation of human adipose-derived stromal cell osteogenic differentiation by insulin-like growth factor-1 and platelet-derived growth factor-alpha
    • Levi B, AW James, DC Wan, JP Glotzbach, GW Commons and MT Longaker. (2010). Regulation of human adipose-derived stromal cell osteogenic differentiation by insulin-like growth factor-1 and platelet-derived growth factor-alpha. Plast Reconstr Surg 126:41-52.
    • (2010) Plast Reconstr Surg , vol.126 , pp. 41-52
    • Levi, B.1    James, A.W.2    Wan, D.C.3    Glotzbach, J.P.4    Commons, G.W.5    Longaker, M.T.6
  • 9
    • 36849010732 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in adipogenesis and metabolism
    • Prestwich TC and OA Macdougald. (2007). Wnt/beta-catenin signaling in adipogenesis and metabolism. Curr Opin Cell Biol 19:612-617.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 612-617
    • Prestwich, T.C.1    MacDougald, O.A.2
  • 10
    • 21244481801 scopus 로고    scopus 로고
    • Wnt signaling inhibits adipogenesis through beta-catenin-dependent and-independent mechanisms
    • Kennell JA and OA MacDougald. (2005). Wnt signaling inhibits adipogenesis through beta-catenin-dependent and-independent mechanisms. J Biol Chem 280:24004-24010.
    • (2005) J Biol Chem , vol.280 , pp. 24004-24010
    • Kennell, J.A.1    MacDougald, O.A.2
  • 11
    • 48349107136 scopus 로고    scopus 로고
    • Roles of Wnt/beta-catenin signaling in adipogenic differentiation potential of adipose-derived mesenchymal stem cells
    • Li HX, X Luo, RX Liu, YJ Yang and GS Yang. (2008). Roles of Wnt/beta-catenin signaling in adipogenic differentiation potential of adipose-derived mesenchymal stem cells. Mol Cell Endocrinol 291:116-124.
    • (2008) Mol Cell Endocrinol , vol.291 , pp. 116-124
    • Li, H.X.1    Luo, X.2    Liu, R.X.3    Yang, Y.J.4    Yang, G.S.5
  • 12
    • 77956079673 scopus 로고    scopus 로고
    • Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells
    • James AW, P Leucht, B Levi, AL Carre, Y Xu, JA Helms and MT Longaker. (2010). Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells. Tissue Eng Part A 16:2605-2616.
    • (2010) Tissue Eng Part A , vol.16 , pp. 2605-2616
    • James, A.W.1    Leucht, P.2    Levi, B.3    Carre, A.L.4    Xu, Y.5    Helms, J.A.6    Longaker, M.T.7
  • 13
    • 33645046358 scopus 로고    scopus 로고
    • Hedgehog signaling plays a conserved role in in-hibiting fat formation
    • Suh JM, X Gao, J McKay, R McKay, Z Salo and JM Graff. (2006). Hedgehog signaling plays a conserved role in in-hibiting fat formation. Cell Metab 3:25-34.
    • (2006) Cell Metab , vol.3 , pp. 25-34
    • Suh, J.M.1    Gao, X.2    McKay, J.3    McKay, R.4    Salo, Z.5    Graff, J.M.6
  • 14
    • 0346996354 scopus 로고    scopus 로고
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells
    • van der Horst G, H Farih-Sips, CW Lowik and M Karperien. (2003). Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells. Bone 33:899-910.
    • (2003) Bone , vol.33 , pp. 899-910
    • Van Der Horst, G.1    Farih-Sips, H.2    Lowik, C.W.3    Karperien, M.4
  • 15
    • 0142124746 scopus 로고    scopus 로고
    • Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion
    • Jemtland R, P Divieti, K Lee and GV Segre. (2003). Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion. Bone 32: 611-620.
    • (2003) Bone , vol.32 , pp. 611-620
    • Jemtland, R.1    Divieti, P.2    Lee, K.3    Segre, G.V.4
  • 16
    • 0034949211 scopus 로고    scopus 로고
    • Sonic hedgehog increases the commitment of pluripotent mesen-chymal cells into the osteoblastic lineage and abolishes adi-pocytic differentiation
    • Spinella-Jaegle S, G Rawadi, S Kawai, S Gallea, C Faucheu, P Mollat, B Courtois, B Bergaud, V Ramez, et al. (2001). Sonic hedgehog increases the commitment of pluripotent mesen-chymal cells into the osteoblastic lineage and abolishes adi-pocytic differentiation. J Cell Sci 114:2085-2094.
    • (2001) J Cell Sci , vol.114 , pp. 2085-2094
    • Spinella-Jaegle, S.1    Rawadi, G.2    Kawai, S.3    Gallea, S.4    Faucheu, C.5    Mollat, P.6    Courtois, B.7    Bergaud, B.8    Ramez, V.9
  • 19
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and dif-ferentiation of chondrocytes and is essential for bone for-mation
    • St.-Jacques B, M Hammerschmidt and AP McMahon. (1999). Indian hedgehog signaling regulates proliferation and dif-ferentiation of chondrocytes and is essential for bone for-mation. Genes Dev 13:2072-2086.
    • (1999) Genes Dev , vol.13 , pp. 2072-2086
    • St.-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 20
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differ-entiation by Indian hedgehog and PTH-related protein
    • Vortkamp A, K Lee, B Lanske, GV Segre, HM Kronenberg and CJ Tabin. (1996). Regulation of rate of cartilage differ-entiation by Indian hedgehog and PTH-related protein. Science 273:613-622.
    • (1996) Science , vol.273 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 21
    • 78951481661 scopus 로고    scopus 로고
    • Human adipose-derived stromal cells stimulate autogenous skeletal repair via paracrine hedgehog signaling with calvarial osteoblasts
    • Levi B, AW James, ER Nelson, S Li, M Peng, GW Commons, M Lee, B Wu and MT Longaker. (2011). Human adipose-derived stromal cells stimulate autogenous skeletal repair via paracrine hedgehog signaling with calvarial osteoblasts. Stem Cells Dev 20:243-257.
    • (2011) Stem Cells Dev , vol.20 , pp. 243-257
    • Levi, B.1    James, A.W.2    Nelson, E.R.3    Li, S.4    Peng, M.5    Commons, G.W.6    Lee, M.7    Wu, B.8    Longaker, M.T.9
  • 22
    • 77956483511 scopus 로고    scopus 로고
    • Paracrine interaction between adipose-derived stromal cells and cranial suture-derived mesenchy-mal cells
    • James AW, B Levi, GW Commons, J Glotzbach and MT Longaker. (2010). Paracrine interaction between adipose-derived stromal cells and cranial suture-derived mesenchy-mal cells. Plast Reconstr Surg 126:806-821.
    • (2010) Plast Reconstr Surg , vol.126 , pp. 806-821
    • James, A.W.1    Levi, B.2    Commons, G.W.3    Glotzbach, J.4    Longaker, M.T.5
  • 26
    • 79952922407 scopus 로고    scopus 로고
    • Nell-1 deficient mice exhibit abnormal structure in spinal and long bones
    • Siu RK, X Zhang, T Ko, BM Wu, K Ting, CT Culiat and C Soo. (2009). Nell-1 deficient mice exhibit abnormal structure in spinal and long bones. ASBMR 2009:S50-51.
    • (2009) ASBMR , vol.2009
    • Siu, R.K.1    Zhang, X.2    Ko, T.3    Wu, B.M.4    Ting, K.5    Culiat, C.T.6    Soo, C.7
  • 31
  • 34
    • 79952146857 scopus 로고    scopus 로고
    • Deleterious effects of freezing on osteogenic differentiation of human adipose-derived stromal cells in vitro and in vivo
    • James AW, B Levi, ER Nelson, M Peng, GW Commons, M Lee, B Wu and MT Longaker. (2010). Deleterious effects of freezing on osteogenic differentiation of human adipose-derived stromal cells in vitro and in vivo. Stem Cells Dev 20:427-439.
    • (2010) Stem Cells Dev , vol.20 , pp. 427-439
    • James, A.W.1    Levi, B.2    Nelson, E.R.3    Peng, M.4    Commons, G.W.5    Lee, M.6    Wu, B.7    Longaker, M.T.8
  • 36
    • 77955373350 scopus 로고    scopus 로고
    • Divergent modulation of adipose-derived stromal cell differentiation by TGF-beta1 based on species of deri-vation
    • Levi B, AW James, Y Xu, GW Commons and MT Longaker. (2010). Divergent modulation of adipose-derived stromal cell differentiation by TGF-beta1 based on species of deri-vation. Plast Reconstr Surg 126:412-425.
    • (2010) Plast Reconstr Surg , vol.126 , pp. 412-425
    • Levi, B.1    James, A.W.2    Xu, Y.3    Commons, G.W.4    Longaker, M.T.5
  • 37
    • 77951848700 scopus 로고    scopus 로고
    • Retinoic acid enhances osteogenesis in cranial suture-derived mesenchymal cells: Potential mechanisms of retinoid-induced craniosynostosis
    • James AW, B Levi, Y Xu, AL Carre and MT Longaker. (2010). Retinoic acid enhances osteogenesis in cranial suture-derived mesenchymal cells: potential mechanisms of retinoid-induced craniosynostosis. Plast Reconstr Surg 125:1352-1361.
    • (2010) Plast Reconstr Surg , vol.125 , pp. 1352-1361
    • James, A.W.1    Levi, B.2    Xu, Y.3    Carre, A.L.4    Longaker, M.T.5
  • 38
    • 77956492086 scopus 로고    scopus 로고
    • Depot-specific variation in the osteogenic and adipogenic potential of human adipose-derived stromal cells
    • Levi B, AW James, JP Glotzbach, DC Wan, GW Commons and MT Longaker. (2010). Depot-specific variation in the osteogenic and adipogenic potential of human adipose-derived stromal cells. Plast Reconstr Surg 126:822-834.
    • (2010) Plast Reconstr Surg , vol.126 , pp. 822-834
    • Levi, B.1    James, A.W.2    Glotzbach, J.P.3    Wan, D.C.4    Commons, G.W.5    Longaker, M.T.6
  • 39
    • 34548765981 scopus 로고    scopus 로고
    • A study of the role of nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation
    • Aghaloo T, X Jiang, C Soo, Z Zhang, X Zhang, J Hu, H Pan, T Hsu, B Wu and K Ting. (2007). A study of the role of nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation. Mol Ther 15:1872-1880.
    • (2007) Mol Ther , vol.15 , pp. 1872-1880
    • Aghaloo, T.1    Jiang, X.2    Soo, C.3    Zhang, Z.4    Zhang, X.5    Hu, J.6    Pan, H.7    Hsu, T.8    Wu, B.9    Ting, K.10
  • 41
    • 26444553353 scopus 로고    scopus 로고
    • Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?
    • Im GI, YW Shin and KB Lee. (2005). Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells? Osteoarthritis Cartilage 13:845-853.
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 845-853
    • Im, G.I.1    Shin, Y.W.2    Lee, K.B.3
  • 44
    • 0031922720 scopus 로고    scopus 로고
    • FGF-, BMP-and Shh-mediated signalling pathways in the regu-lation of cranial suture morphogenesis and calvarial bone development
    • Kim HJ, DP Rice, PJ Kettunen and I Thesleff. (1998). FGF-, BMP-and Shh-mediated signalling pathways in the regu-lation of cranial suture morphogenesis and calvarial bone development. Development 125:1241-1251.
    • (1998) Development , vol.125 , pp. 1241-1251
    • Kim, H.J.1    Rice, D.P.2    Kettunen, P.J.3    Thesleff, I.4
  • 45
    • 34848818790 scopus 로고    scopus 로고
    • Regulation of skeletogenic differentiation in cranial dermal bone
    • Abzhanov A, SJ Rodda, AP McMahon and CJ Tabin. (2007). Regulation of skeletogenic differentiation in cranial dermal bone. Development 134:3133-3144.
    • (2007) Development , vol.134 , pp. 3133-3144
    • Abzhanov, A.1    Rodda, S.J.2    McMahon, A.P.3    Tabin, C.J.4
  • 47
    • 0032008025 scopus 로고    scopus 로고
    • Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair
    • Vortkamp A, S Pathi, GM Peretti, EM Caruso, DJ Zaleske and CJ Tabin. (1998). Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair. Mech Dev 71:65-76.
    • (1998) Mech Dev , vol.71 , pp. 65-76
    • Vortkamp, A.1    Pathi, S.2    Peretti, G.M.3    Caruso, E.M.4    Zaleske, D.J.5    Tabin, C.J.6
  • 48
    • 0028837742 scopus 로고
    • Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell in-teraction in the mouse embryo
    • Bitgood MJ and AP McMahon. (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell in-teraction in the mouse embryo. Dev Biol 172:126-138.
    • (1995) Dev Biol , vol.172 , pp. 126-138
    • Bitgood, M.J.1    McMahon, A.P.2
  • 50
    • 77953849413 scopus 로고    scopus 로고
    • Effect of Nell-1 delivery on chondrocyte proliferation and cartilaginous ex-tracellular matrix deposition
    • Lee M, RK Siu, K Ting and BM Wu. (2010). Effect of Nell-1 delivery on chondrocyte proliferation and cartilaginous ex-tracellular matrix deposition. Tissue Eng Part A 16:1791-1800.
    • (2010) Tissue Eng Part A , vol.16 , pp. 1791-1800
    • Lee, M.1    Siu, R.K.2    Ting, K.3    Wu, B.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.