The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

Nature Structural and Molecular Biology

Volumn 19, Issue 8, 2012, Pages 767-772

  Koehnke, Jesko ^a   Bent, Andrew ^a   Houssen, Wael E ^b,c   Zollman, David ^a   Morawitz, Falk ^a   Shirran, Sally ^a   Vendome, Jeremie ^d   Nneoyiegbe, Ada F ^b   Trembleau, Laurent ^b   Botting, Catherine H ^a   Smith, Margaret C M ^c   Jaspars, Marcel ^b   Naismith, James H ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROCYCLIC COMPOUND; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; PATELLAMIDE; SUBTILISIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL MODIFICATION; CYCLIZATION; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; MODELS, MOLECULAR; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PROCHLORON; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SUBTILISINS; SYMBIOSIS; UROCHORDATA;

PROCHLORON SP.;

EID: 84864709843     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2340     Document Type: Article

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