Comprehensive review of the diagnosis and treatment of biliary tract cancer 2012. PART I: Diagnosis-clinical staging and pathology

Journal of Surgical Oncology

Volumn 106, Issue 3, 2012, Pages 332-338

  Marsh, Robert De W ^a   Alonzo, Marc ^a   Bajaj, Shailesh ^a   Baker, Marshall ^a   Elton, Eric ^a   Farrell, Thomas A ^a   Gore, Richard M ^a   Hall, Curtis ^a   Nowak, Jan ^a   Roy, Hemant ^a   Shaikh, Arif ^a   Talamonti, Mark S ^a  

^a NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

Author keywords

chemotherapy; cholangiocarcinoma; gallbladder cancer; radiation; surgery

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; K RAS PROTEIN; PROTEIN P53;

ASPIRATION BIOPSY; BILE DUCT CARCINOMA; BILIARY TRACT CANCER; CANCER CLASSIFICATION; CANCER LOCALIZATION; CANCER MORPHOLOGY; CANCER SIZE; CANCER STAGING; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; ENDOSCOPIC ECHOGRAPHY; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; GALLBLADDER CANCER; GALLBLADDER CARCINOMA; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HUMAN; LOW COHERENCE ENHANCED BACKSCATTERING SPECTROSCOPY; MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY; MOLECULAR PATHOLOGY; MULTIDETECTOR COMPUTED TOMOGRAPHY; MUTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REVIEW; SPECTROSCOPY;

AMPULLA OF VATER; BILE DUCTS, EXTRAHEPATIC; BILE DUCTS, INTRAHEPATIC; BILIARY TRACT NEOPLASMS; CARCINOMA; CHROMOSOME ABERRATIONS; DIAGNOSTIC IMAGING; ENDOSCOPY, DIGESTIVE SYSTEM; GALLBLADDER; GENE EXPRESSION PROFILING; HUMANS; MICRORNAS; MUTATION; NEOPLASM STAGING; SPECTRUM ANALYSIS;

EID: 84864704636     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.23028     Document Type: Review

References (79)

1. Jemal A, Siegal R, Xu J, et al.: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
2. Choi BI, Lee JM,: Neoplasms of the gallbladder and biliary tract. In:, Gore RM, Levine MS, editors. Textbook of gastrointestinal radiology, 3rd edition. Philadelphia: W. B. Saunders; 2008; p. 1517-1526.
3. Gore RM, Thakrar KH, Newmark GM, et al.: Gallbladder imaging. Gastroenterol Clin North Am 2010; 39: 265-287, ix.
4. Kim MJ, Choi JY, Chung YE,: Evaluation of biliary malignancies using multidetector-row computed tomography. J Comput Assist Tomogr 2010; 34: 496-505.
5. Gakhal MS, et al.: Multimodality imaging of biliary malignancies. Surg Oncol Clin N Am 2009; 18: 225-239, vii-viii.
6. Gore RM, Shelhamer RP,: Biliary tract neoplasms: Diagnosis and staging. Cancer Imaging 2007; 7: S15-S23.
7. Park M-S, et al.: Differentiation of extrahepatic bile duct cholangiocarcinoma from benign stricture: Findings at MRCP versus ERCP. Radiology 2004; 233: 234-240.
8. Fritcher EG, et al.: A multivariable model using advanced cytologic methods for the evaluation of indeterminate pancreatobiliary strictures. Gastroenterology 2009; 136: 2180-2186.
9. Domagk D, et al.: Endoscopic transpapillary biopsies and intraductal ultrasonography in the diagnostics of bile duct strictures: A prospective study. Gut 2002; 51: 240-244.
10. Siqueira E, et al.: Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis. Gastrointest Endosc 2002; 56: 40-47.
11. Furmanczyk PS, Grieco VS, Agoff SN,: Biliary brush cytology and the detection of cholangiocarcinoma in primary sclerosing cholangitis: Evaluation of specific cytomorphologic features and CA19-9 levels. Am J Clin Pathol 2005; 124: 355-360.
12. Boberg KM, et al.: Diagnostic benefit of biliary brush cytology in cholangiocarcinoma in primary sclerosing cholangitis. J Hepatol 2006; 45: 568-574.
13. Stewart CJ, et al.: Brush cytology in the assessment of pancreatico-biliary strictures: A review of 406 cases. J Clin Pathol 2001; 54: 449-455.
14. Ponchon T, et al.: Value of endobiliary brush cytology and biopsies for the diagnosis of malignant bile duct stenosis: Results of a prospective study. Gastrointest Endosc 1995; 42: 565-572.
15. Schoefl R, et al.: Forceps biopsy and brush cytology during endoscopic retrograde cholangiopancreatography for the diagnosis of biliary stenoses. Scand J Gastroenterol 1997; 32: 363-368.
16. Farrell RJ, et al.: The combination of stricture dilation, endoscopic needle aspiration, and biliary brushings significantly improves diagnostic yield from malignant bile duct strictures. Gastrointest Endosc 2001; 54: 587-594.
17. Kipp BR, et al.: Comparison of KRAS mutation analysis and FISH for detecting pancreatobiliary tract cancer in cytology specimens collected during endoscopic retrograde cholangiopancreatography. J Mol Diagn 2010; 12: 780-786.
18. Choi HJ, et al.: Overtube-balloon-assisted direct peroral cholangioscopy by using an ultra-slim upper endoscope (with videos). Gastrointest Endosc 2009; 69: 935-940.
19. Nguyen NQ, Shah JN, Binmoeller KF,: Diagnostic cholangioscopy with SpyGlass probe through an endoscopic retrograde cholangiopancreatography cannula. Endoscopy 2010; 42: E288-E289.
20. Chen YK, Pleskow DK,: SpyGlass single-operator peroral cholangiopancreatoscopy system for the diagnosis and therapy of bile-duct disorders: A clinical feasibility study (with video). Gastrointest Endosc 2007; 65: 832-841.
21. Mohamadnejad M, DeWitt JM, Sherman S, et al.: Role of EUS for preoperative evaluation of cholangiocarcinoma: A large single-center experience. Gastrointest Endosc 2011; 73: 71-78.
22. DeWitt J, et al.: EUS-guided FNA of proximal biliary strictures after negative ERCP brush cytology results. Gastrointest Endosc 2006; 64: 325-333.
23. Garrow D, et al.: Endoscopic ultrasound: A meta-analysis of test performance in suspected biliary obstruction. Clin Gastroenterol Hepatol 2007; 5: 616-623.
24. Dumortier J, et al.: Successful liver transplantation for diffuse biliary papillomatosis. J Hepatol 2001; 35: 542-543.
25. Wehrmann T, et al.: Intraductal ultrasonography in the diagnosis of Mirizzi syndrome. Endoscopy 2006; 38: 717-722.
26. Tamada K, et al.: Assessment of hepatic artery invasion by bile duct cancer using intraductal ultrasonography. Endoscopy 1995; 27: 579-583.
27. Tamada K, et al.: Assessment of portal vein invasion by bile duct cancer using intraductal ultrasonography. Endoscopy 1995; 27: 573-578.
28. Napoleon B, Lefort C,: IDUS: Diagnosis of bile duct carcinoma. Dig Endosc 2004; 16: S230-S235.
29. Backman V, Roy HK,: Light-scattering technologies for field carcinogenesis detection: A modality for endoscopic prescreening. Gastroenterology 2011; 140: 35-41.
30. Subramanian H, et al.: Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy. Cancer Res 2009; 69: 5357-5363.
31. Roy HK, Subramanian H, Damania D, et al.: Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: Implications for screening. Cancer Res 2010; 70: 7748-7754.
32. Katabi N,: Neoplasia of gallbladder and biliary epithelium. Arch Pathol Lab Med 2010; 134: 1621-1627.
33. Adsay NV, Klimstra DS,: Benign and malignant tumors of the gallbladder and extrahepatic biliary tract in Surgical pathology of the GI tract, liver, biliary tract, and pancreas. Philadelphia: Saunders Elsevier; 2009. p. 853-870.
34. Adsay NV, Klimstra DS,: Tumors of the pancreas and ampulla of Vater in Surgical pathology of the GI tract, liver, biliary tract, and pancreas. Philadelphia: Saunders Elsevier; 2009. p. 949-956.
35. Ferrell LD,: Benign and malignant tumors of the liver in Surgical pathology in the GI tract, liver, biliary tract, and pancreas. Philadelphia: Saunders Elsevier; 2009. p. 1311-1313.
36. Edge SB, Byrd DR, Compton CC, et al.: editors. Distal bile duct in AJCC cancer staging manual. 7th edition. New York: Springer; 2010. 227-233.
37. Edge SB, Byrd DR, Compton CC, et al.: editors. Intrahepatic bile ducts in AJCC cancer staging manual. 7th edition. New York: Springer; 2010. 210-219.
38. Edge SB, Byrd DR, Compton CC, et al.: editors. Gallbladder in cancer AJCC staging manual. 7th edition. New York: Springer; 2010. 211-217.
39. Edge SB, Byrd DR, Compton CC, et al.: editors. Perihilar bile ducts in AJCC cancer stagin manual. 7th edition. New York: Springer; 2010. 219-225.
40. Edge SB, Byrd DR, Compton CC, et al.: editors. Ampulla of Vater in AJCC cancer staging manual. 7th edition. New York: Springer; 2010. 235-240.
41. Lewis JT, Talwalkar JA, Rosen CB, et al.: Precancerous bile duct pathology in end-stage primary sclerosing cholangitis, with and without cholangiocarcinoma. Am J Surg Pathol 2010; 34: 27-34.
42. Lewis JT, Talwalkar JA, Rosen CB, et al.: Prevalence and risk factors for gallbladder neoplasia in patients with primary sclerosing cholangitis: Evidence for a metaplasia-dysplasia-carcinoma sequence. Am J Surg Pathol 2007; 31: 907-913.
43. Laitio M,: Carcinoma of extrahepatic bile ducts. A histopathologic study. Pathol Res Pract 1983; 178: 67-72.
44. Seifert E, Schulte F, Stolte M,: Adenoma and carcinoma of the duodenum and papilla of Vater: A clinicopathologic study. Am J Gastroenterol 1992; 87: 37-42.
45. Wise C, et al.: Mechanisms of biliary carcinogenesis and growth. World J Gastroenterol 2008; 14: 2986-2989.
46. Shafizadeh N, et al.: Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder. Hum Pathol 2010; 41: 485-492.
47. Goldin RD, Roa JC,: Gallbladder cancer: A morphological and molecular update. Histopathology 2009; 55: 218-229.
48. Albores-Saavedra J, Henson DE, Klimstra DS,: Pathology of invasive carcinoma of the gallbladder tumors of the gallbladder, extrahepatic bile ducts, and ampulla of vater, Vol. 27. Washington D.C.: Armed Forces Institute of Pathology; 2000.
49. Albores-Saavedra J, Henson DE, Klimstra DS,: Dysplasia, carcinoma in situ, and invasive carcinoma of the extrahepatic bile ducts. tumors of the gallbladder, extrahepatic bile ducts, and ampulla of vater, Vol. 27. Washington D.C.: Armed Forces Institute of Pathology; 2000.
50. Ligato S, et al.: KOC (K homology domain containing protein overexpressed in cancer) and S100A4-protein immunoreactivity improves the diagnostic sensitivity of biliary brushing cytology for diagnosing pancreaticobiliary malignancies. Diagn Cytopathol 2008; 36: 561-567.
51. Westgaard A, et al.: Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma. BMC Cancer 2008; 8: 170.
52. Heinrich S, Clavien PA,: Ampullary cancer. Curr Opin Gastroenterol 2010; 26: 280-285.
53. Albores-Saavedra J, Henson DE, Klimstra DS,: Malignant epithelial tumors of the ampulla tumors of the gallbladder, extrahepatic bile ducts, and ampulla of vater, Vol. 27. Washington DC: Armed Forces Institute of Pathology; 2000.
54. Wistuba II, Gazdar AF,: Gallbladder cancer: Lessons from a rare tumour. Nat Rev Cancer 2004; 4: 695-706.
55. Jarnagin WR, et al.: Differential cell cycle-regulatory protein expression in biliary tract adenocarcinoma: Correlation with anatomic site, pathologic variables, and clinical outcome. J Clin Oncol 2006; 24: 1152-1160.
56. Miyahara N, et al.: MUC4 interacts with ErbB2 in human gallbladder carcinoma: Potential pathobiological implications. Eur J Cancer 2008; 44: 1048-1056.
57. Shiraishi K, et al.: Genetic aberrations detected by comparative genomic hybridization in biliary tract cancers. Oncology 1999; 57: 42-49.
58. Koo SH, et al.: Genetic alterations in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Cancer Genet Cytogenet 2001; 130: 22-28.
59. Lee JY, et al.: Genetic alterations in intrahepatic cholangiocarcinoma as revealed by degenerate oligonucleotide primed PCR-comparative genomic hybridization. J Korean Med Sci 2004; 19: 682-687.
60. Saito S, et al.: The genetic differences between gallbladder and bile duct cancer cell lines. Oncol Rep 2006; 16: 949-956.
61. Koo SH, et al.: Microsatellite alterations in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Cancer Genet Cytogenet 2003; 146: 139-144.
62. Wistuba II, et al.: Genome-wide allelotyping analysis reveals multiple sites of allelic loss in gallbladder carcinoma. Cancer Res 2001; 61: 3795-3800.
63. Wistuba II, et al.: High resolution chromosome 3p, 8p, 9q and 22q allelotyping analysis in the pathogenesis of gallbladder carcinoma. Br J Cancer 2002; 87: 432-440.
64. Fritcher EG, Halling KC,: Advanced cytologic approaches for the diagnosis of pancreatobiliary cancer. Curr Opin Gastroenterol 2010; 26: 259-264.
65. Kipp BR, et al.: A comparison of routine cytology and fluorescence in situ hybridization for the detection of malignant bile duct strictures. Am J Gastroenterol 2004; 99: 1675-1681.
66. Khalid A, et al.: Use of microsatellite marker loss of heterozygosity in accurate diagnosis of pancreaticobiliary malignancy from brush cytology samples. Gut 2004; 53: 1860-1865.
67. Lapkus O, et al.: Determination of sequential mutation accumulation in pancreas and bile duct brushing cytology. Mod Pathol 2006; 19: 907-913.
68. Miller AM, Zhang JX,: Altered endothelin-1 signaling in production of thromboxane A2 in kupffer cells from bile duct ligated rats. Cell Mol Immunol 2009; 6: 441-452.
69. Parsi MA, et al.: DNA methylation alterations in endoscopic retrograde cholangiopancreatography brush samples of patients with suspected pancreaticobiliary disease. Clin Gastroenterol Hepatol 2008; 6: 1270-1278.
70. Monzon FA, et al.: Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression test. Diagn Pathol 2010; 5: 3.
71. Simon R,: Roadmap for developing and validating therapeutically relevant genomic classifiers. J Clin Oncol 2005; 23: 7332-7341.
72. Simon R, et al.: Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification. J Natl Cancer Inst 2003; 95: 14-18.
73. Jennings L, Van Deerlin VM, Gulley ML,: Recommended principles and practices for validating clinical molecular pathology tests. Arch Pathol Lab Med 2009; 133: 743-755.
74. Dumur CI, et al.: Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers. J Mol Diagn 2008; 10: 67-77.
75. Monzon FA, et al.: Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin. J Clin Oncol 2009; 27: 2503-2508.
76. Meng F, et al.: Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 2006; 130: 2113-2129.
77. Meng F, et al.: Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene 2008; 27: 378-386.
78. Kawahigashi Y, et al.: MicroRNA profiling of human intrahepatic cholangiocarcinoma cell lines reveals biliary epithelial cell-specific microRNAs. J Nippon Med Sch 2009; 76: 188-197.
79. Selaru FM, et al.: MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology 2009; 49: 1595-1601.