A phase 2 trial of combination therapy with thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid (TADA) in patients with overlap myelodysplastic/myeloproliferative neoplasms (MDS/MPN) or primary myelofibrosis (PMF)

Cancer

Volumn 118, Issue 16, 2012, Pages 3968-3976

  Bejanyan, Nelli ^a   Tiu, Ramon V ^a   Raza, Azra ^b   Jankowska, Ania ^a   Kalaycio, Matt ^a   Advani, Anjali ^a   Chan, Josephine ^a   Saunthararajah, Yogen ^a   Mooney, Lindsey ^a   MacIejewski, Jaroslaw P ^a   Sekeres, Mikkael A ^a  

^a TAUSSIG CANCER INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

and ascorbic acid; arsenic trioxide; dexamethasone; myelodysplastic myeloproliferative neoplasms; myelofibrosis; primary myelofibrosis; thalidomide; trial

Indexed keywords

ANAGRELIDE; ANTIANEMIC AGENT; ARSENIC TRIOXIDE; ASCORBIC ACID; AZACITIDINE; CELL PROTEIN; DEXAMETHASONE; DIURETIC AGENT; HYDROXYUREA; JANUS KINASE 2; PREDNISONE; PROTEIN TET2; THALIDOMIDE; UNCLASSIFIED DRUG;

ADULT; AGED; ALOPECIA; ANEMIA; ANOREXIA; ANXIETY; ARTICLE; BLOOD TOXICITY; BONE PAIN; CARDIOGENIC EDEMA; CARDIOVASCULAR DISEASE; CHILL; CHRONIC MYELOMONOCYTIC LEUKEMIA; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONFUSION; CONSTIPATION; COUGHING; CYTOGENETICS; DEHYDRATION; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG ERUPTION; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG SAFETY; DYSPEPSIA; DYSPNEA; EDEMA; ELECTROLYTE DISTURBANCE; EPISTAXIS; FATIGUE; FLUID OVERLOAD; FOLLOW UP; GASTROINTESTINAL SYMPTOM; GENE MUTATION; HEARING DISORDER; HEART ATRIUM FIBRILLATION; HEART TAMPONADE; HUMAN; HYPERTENSION; HYPERTRANSAMINASEMIA; HYPOMAGNESEMIA; HYPOTENSION; HYPOXIA; INFECTION; KIDNEY FAILURE; LEG SWELLING; LEUKOCYTOSIS; LYMPHADENOPATHY; MAINTENANCE CHEMOTHERAPY; METABOLIC DISORDER; MICTURITION DISORDER; MIXED MYELODYSPLASTIC MYELOPROLIFERATIVE DISEASE; MULTICENTER STUDY; MUSCULOSKELETAL DISEASE; MYALGIA; MYELOID METAPLASIA; NAUSEA; NEUROPATHY; NEUROTOXICITY; NEUTROPENIA; NIGHT SWEAT; OPEN STUDY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; PIGMENT DISORDER; PLEURA EFFUSION; PNEUMONIA; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PRURITUS; QT PROLONGATION; RESPIRATORY TRACT DISEASE; RIGOR; SEXUAL DYSFUNCTION; SIDE EFFECT; SKIN BRUISING; SKIN TOXICITY; SLEEP DISORDER; SPLENOMEGALY; TACHYCARDIA; THROMBOCYTOPENIA; THROMBOSIS; TREATMENT DURATION; TREATMENT RESPONSE; UROGENITAL TRACT DISEASE; VISUAL DISORDER; VOMITING; WEIGHT CHANGE; XEROSTOMIA;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ARSENICALS; ASCORBIC ACID; DEXAMETHASONE; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MYELODYSPLASTIC-MYELOPROLIFERATIVE DISEASES; OXIDES; PRIMARY MYELOFIBROSIS; THALIDOMIDE;

EID: 84864696330     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26741     Document Type: Article

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