Association of His1085His INSR gene polymorphism with type 2 diabetes in South Indians

Diabetes Technology and Therapeutics

Volumn 14, Issue 8, 2012, Pages 696-700

  Bodhini, Dhanasekaran ^a   Sandhiya, Mohanram ^a   Ghosh, Saurabh ^b   Majumder, Partha P ^c   Rao, M R Satyanarayana ^d   Mohan, Viswanathan ^a   Radha, Venkatesan ^a  

^a MADRAS DIABETES RESEARCH FOUNDATION   (India)

^b INDIAN STATISTICAL INSTITUTE   (India)

^c NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS   (India)

^d JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; INSULIN RECEPTOR; PROTEIN TYROSINE KINASE;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC VARIABILITY; GENOTYPE; GLUCOSE TOLERANCE; HUMAN; INDIAN; INSULIN BINDING; INSULIN RECEPTOR GENE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANTIGENS, CD; DIABETES MELLITUS, TYPE 2; DNA MUTATIONAL ANALYSIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; MALE; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, INSULIN;

EID: 84864692732     PISSN: 15209156     EISSN: 15578593     Source Type: Journal    
DOI: 10.1089/dia.2012.0009     Document Type: Article

References (22)

1. Sesti G, Federici M, Lauro D, Sbraccia P, Lauro R: Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms. Diabetes Metab Res Rev 2001;17:363-373.
2. Seino S, Seino M, Nishi S, Bell GI: Structure of the human insulin receptor gene and characterization of its promoter. Proc Natl Acad Sci US A 1989;86:114-118.
3. Seino S, Seino M, Bell GI: Human insulin receptor gene: partial sequence and amplification of exons by polymerase chain reaction. Diabetes 1990;39:129-133.
4. Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, Unnikrishnan R, Bhansali A, Joshi SR, Joshi PP, Yajnik CS, Dhandhania VK, Nath LM, Das AK, Rao PV, Madhu SV, Shukla DK, Kaur T, Priya M, Nirmal E, Parvathi SJ, Subhashini S, Subashini R, Ali MK, Mohan V; ICMR-INDIAB Collaborative Study Group: Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: phase I results of the Indian Council of Medical Research-INdiaDIABetes (ICMR-INDIAB) study. Diabetologia 2011;54:3022-3027.
5. Sharp PS, Mohan V, Levy JC, Mather HM, Kohner EM: Insulin resistance in patients of Asian Indian and European origin with non-insulin dependent diabetes. Horm Metab Res 1987;19:84-85.
6. Mohan V, Sharp PS, Aber V, Mather HM, Kohner EM: Family histories of Asian Indian and European NIDDM patients. Pract Diabetes 1986;3:254-256.
7. Radha V, Mohan V: Genetic predisposition to type 2 diabetes among Asian Indians. Indian J Med Res 2007;125: 259-274.
8. Deepa M, Pradeepa R, Rema M, Anjana M, Deepa R, Shanthirani S: The Chennai Urban Rural Epidemiology Study (CURES)-study design and methodology (urban component) (CURES-1). J Assoc Physicians India 2003; 51:863-870.
9. Alberti KG, Zimmet PZ: Definition diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, provisional report of a WHO Consultation. Diabet Med 1998;15: 539-553.
10. Kusari J, Verma US, Buse JB, Henry RR, Olefsky JM: Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. J Clin Invest 1991;88:1323-1330.
11. O'Rahilly S, Choi WH, Pate P, Turner RC, Flier JS, Moller DE: Detection of mutations in the insulin receptor gene in non-insulin dependent diabetic patients by analysis of single-stranded conformation polymorphisms. Diabetes 1991;40:777-782.
12. Cocozza S, Porcellini A, Riccardi G, Monticelli A, Condorelli G, Ferrara A, Pianese, L, Miele C, Capaldo B, Beguinot F: NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene. Diabetes 1992;41:521-526.
13. Wang L, Mi J, Zhao XY, Wu JX, Cheng H, Zhang ZK, Ding XY, Hou DQ, Li H: Polymorphisms of exon 17 of insulinreceptor gene in pathogenesis of human disorders with insulin resistance. Biomed Environ Sci 2004;17:418-425.
14. Kadowaki T, Kadowaki H, Rechler MM, Serrano-Rios M, Roth J, Gorden P, Taylor SI: Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance. J Clin Invest 1990;86:254-264.
15. Kim H, Kadowaki H, Sakura H, Odawara M, Momomura K, Takahashi Y, Miyazaki Y, Ohtani T, Akanuma Y, Yazaki Y, Kasuga M, Taylor SI, Kadowaki T: Detection of mutations in the insulin receptor gene in patients with insulin resistance by analysis of single-stranded conformational polymorphisms. Diabetologia 1992;35:261-266.
16. Moller DE, Cohen O, Yamaguchi Y, Assiz R, Grigorescu F, Eberle A, Morrow LA, Moses AC, Flier JS: Prevalence of mutations in the insulin receptor gene in subjects with features of the Type A syndrome of insulin resistance. Diabetes 1994;43:247-255.
17. Krook A, Kumar S, Laing I, Boulton AJM, Wass JAH, O'Rahilly S: Molecular scanning of the insulin receptor gene in syndromes of insulin resistance. Diabetes 1994;43: 357-368.
18. Hansen L, Hansen T, Clausen JO, Echwald SM, Urhammer SA, Rasmussen SK, Pedersen O: The Val985Met insulinreceptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance. Am J Hum Genet 1997;60:1532-1535.
19. Chen ZJ, Shi YH, Zhao YR, Li Y, Tang R, Zhao LX, Cahng ZH: [Correlation between single nucleotide polymorphism of insulin receptor gene with polycystic ovary syndrome]. Zhonghua Fu Chan KeZaZhi 2004;39:582-585.
20. Siegel S, Futterweit W, Davies TF, Concepcion ES, Greenberg DA, Villanueva R, Tomer Y: A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome. Fertil Steril 2002;78:1240-1243.
21. Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM: A silent polymorphism in the MDR1 gene changes substrate specificity. Science 2007;315:525-528.
22. Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Deepa R, Babu HN, Rao MR, Mohan V: Peroxisome proliferatoractivated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians. Diabet Med 2005;22:1516-1521.