메뉴 건너뛰기




Volumn 4, Issue 4, 2012, Pages 647-657

Characterization of PAR1 and FGFR1 expression in invasive breast carcinomas: Prognostic significance

Author keywords

Fibroblast growth factor receptor 1; Invasive breast cancer; Protease activated receptor 1

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; FORMALDEHYDE; MOLECULAR MARKER; PARAFFIN; PROTEINASE ACTIVATED RECEPTOR 1;

EID: 84864690484     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.806     Document Type: Article
Times cited : (7)

References (33)
  • 2
    • 75649149550 scopus 로고    scopus 로고
    • Histological and molecular types of breast cancer: Is there a unifying taxonomy?
    • Weigelt B and Reis-Filho JS: Histological and molecular types of breast cancer: is there a unifying taxonomy? Nat Rev Clin Oncol 6: 718-730, 2009.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 718-730
    • Weigelt, B.1    Reis-Filho, J.S.2
  • 3
    • 53149133527 scopus 로고    scopus 로고
    • Refinement of breast cancer classification by molecular characterization of histological special types
    • Weigelt B, Horlings HM, Kreike B, et al: Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol 216: 141-150, 2008.
    • (2008) J Pathol , vol.216 , pp. 141-150
    • Weigelt, B.1    Horlings, H.M.2    Kreike, B.3
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 43549114776 scopus 로고    scopus 로고
    • Current status of prognostic profiling in breast cancer
    • Pusztai L: Current status of prognostic profiling in breast cancer. Oncologist 13: 350-360, 2008.
    • (2008) Oncologist , vol.13 , pp. 350-360
    • Pusztai, L.1
  • 6
    • 0037308089 scopus 로고    scopus 로고
    • Oncogenic transformation induces tumour angiogenesis: A role for PAR1 activation
    • Yin YJ, Salah Z, Maoz M, et al: Oncogenic transformation induces tumour angiogenesis: a role for PAR1 activation. FASEB J 17: 163-174, 2003.
    • (2003) FASEB J , vol.17 , pp. 163-174
    • Yin, Y.J.1    Salah, Z.2    Maoz, M.3
  • 7
    • 34547401519 scopus 로고    scopus 로고
    • Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2
    • Winter SF, Acevedo VD, Gangula RD, et al: Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2. Oncogene 26: 4897-4907, 2007.
    • (2007) Oncogene , vol.26 , pp. 4897-4907
    • Winter, S.F.1    Acevedo, V.D.2    Gangula, R.D.3
  • 8
    • 54049128201 scopus 로고    scopus 로고
    • Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer
    • Agarwal A, Covic L, Sevigny LM, et al: Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol Cancer Ther 7: 2746-2757, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2746-2757
    • Agarwal, A.1    Covic, L.2    Sevigny, L.M.3
  • 9
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TK, Hung DT, Wheaton VI and Coughlin SR: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64: 1057-1068, 1991.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 10
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS and Brass LF: Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem 275: 13502-13509, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6    Brass, L.F.7
  • 11
    • 13544255506 scopus 로고    scopus 로고
    • PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumourigenesis of breast cancer cells
    • Boire A, Covic L, Agarwal A, et al: PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumourigenesis of breast cancer cells. Cell 120: 303-313, 2005.
    • (2005) Cell , vol.120 , pp. 303-313
    • Boire, A.1    Covic, L.2    Agarwal, A.3
  • 12
    • 0035574443 scopus 로고    scopus 로고
    • Thrombin causes vascular endothelial growth factor expression in vascular smooth muscle cells: Role of reactive oxygen species
    • Bassus S, Herkert O, Kronemann N, et al: Thrombin causes vascular endothelial growth factor expression in vascular smooth muscle cells: role of reactive oxygen species. Arterioscler Thromb Vasc Biol 21: 1550-1555, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1550-1555
    • Bassus, S.1    Herkert, O.2    Kronemann, N.3
  • 13
    • 33749621042 scopus 로고    scopus 로고
    • Thrombin induces rapid PAR1-mediated non-classical FGF1 release
    • Duarte M, Kolev V, Soldi R, et al: Thrombin induces rapid PAR1-mediated non-classical FGF1 release. Biochem Biophys Res Commun 350: 604-609, 2006.
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 604-609
    • Duarte, M.1    Kolev, V.2    Soldi, R.3
  • 14
    • 0030034469 scopus 로고    scopus 로고
    • G-protein coupled and tyrosine kinase receptors: Evidence that activation of the insulin-like growth factor I receptor is required for thrombin induced mitogenesis of rat aortic smooth muscle cells
    • Delafontaine P, Anwar A, Lou H and Ku L: G-protein coupled and tyrosine kinase receptors: evidence that activation of the insulin-like growth factor I receptor is required for thrombin induced mitogenesis of rat aortic smooth muscle cells. J Clin Invest 97: 139-145, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 139-145
    • Delafontaine, P.1    Anwar, A.2    Lou, H.3    Ku, L.4
  • 15
    • 1242297568 scopus 로고    scopus 로고
    • Thrombin- and factor Xa-induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells
    • Rauch BH, Millette E, Kenagy RD, et al: Thrombin- and factor Xa-induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells. Circ Res 94: 340-345, 2004.
    • (2004) Circ Res , vol.94 , pp. 340-345
    • Rauch, B.H.1    Millette, E.2    Kenagy, R.D.3
  • 16
    • 67650234471 scopus 로고    scopus 로고
    • PAR1 is selectively over expressed in high grade breast cancer patients: A cohort study
    • Hernandez NA, Correa E, Avila EP, et al: PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study. J Transl Med 7: 47, 2009.
    • (2009) J Transl Med , vol.7 , pp. 47
    • Hernandez, N.A.1    Correa, E.2    Avila, E.P.3
  • 17
    • 0034969753 scopus 로고    scopus 로고
    • Differential expression of protease activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues
    • D'Andrea MR, Derian CK, Santulli RJ and Andrade-Gordon P: Differential expression of protease activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues. Am J Pathol 158: 2031-2041, 2001.
    • (2001) Am J Pathol , vol.158 , pp. 2031-2041
    • D'Andrea, M.R.1    Derian, C.K.2    Santulli, R.J.3    Andrade-Gordon, P.4
  • 18
    • 70249146546 scopus 로고    scopus 로고
    • Fibroblast growth factors in development and cancer: Insights from the mammary and prostate glands
    • Schwertfeger KL: Fibroblast growth factors in development and cancer: insights from the mammary and prostate glands. Curr Drug Targets 10: 632-644, 2009.
    • (2009) Curr Drug Targets , vol.10 , pp. 632-644
    • Schwertfeger, K.L.1
  • 19
    • 0037071550 scopus 로고    scopus 로고
    • Inducible dimerization of FGFR1: Development of a mouse model to analyze progressive transformation of the mammary gland
    • Welm BE, Freeman KW, Chen M, et al: Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol 157: 703-714, 2002.
    • (2002) J Cell Biol , vol.157 , pp. 703-714
    • Welm, B.E.1    Freeman, K.W.2    Chen, M.3
  • 20
    • 0030753515 scopus 로고    scopus 로고
    • Angiogenesis in breast cancer is related to age but not to other prognostic parameters
    • Marinho A, Soares R, Ferro J, et al: Angiogenesis in breast cancer is related to age but not to other prognostic parameters. Pathol Res Pract 193: 267-273, 1997.
    • (1997) Pathol Res Pract , vol.193 , pp. 267-273
    • Marinho, A.1    Soares, R.2    Ferro, J.3
  • 21
    • 28344454000 scopus 로고    scopus 로고
    • Molecular classification and molecular forecasting of breast cancer: Ready for clinical application?
    • Brenton JD, Carey LA, Ahmed AA and Caldas C: Molecular classification and molecular forecasting of breast cancer: ready for clinical application? J Clin Oncol 23: 7350-7360, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 7350-7360
    • Brenton, J.D.1    Carey, L.A.2    Ahmed, A.A.3    Caldas, C.4
  • 22
    • 47049094012 scopus 로고    scopus 로고
    • Breast carcinomas that co-express E- and P-cadherin are associated with p120-catenin cytoplasmic localisation and poor patient survival
    • Paredes J, Correia AL, Ribeiro AS, et al: Breast carcinomas that co-express E- and P-cadherin are associated with p120-catenin cytoplasmic localisation and poor patient survival. J Clin Pathol 61: 856-862, 2008.
    • (2008) J Clin Pathol , vol.61 , pp. 856-862
    • Paredes, J.1    Correia, A.L.2    Ribeiro, A.S.3
  • 23
    • 0036172179 scopus 로고    scopus 로고
    • P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast
    • Paredes J, Milanezi F, Viegas L, et al: P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast. Virchows Arch 440: 16-21, 2002.
    • (2002) Virchows Arch , vol.440 , pp. 16-21
    • Paredes, J.1    Milanezi, F.2    Viegas, L.3
  • 24
    • 68049143326 scopus 로고    scopus 로고
    • Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumour survival and metastasis
    • Yang E, Boire A, Agarwal A, et al: Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumour survival and metastasis. Cancer Res 69: 6223-6231, 2009.
    • (2009) Cancer Res , vol.69 , pp. 6223-6231
    • Yang, E.1    Boire, A.2    Agarwal, A.3
  • 25
    • 0031927754 scopus 로고    scopus 로고
    • Thrombin receptor overexpression in malignant and physiological invasion processes
    • Even-Ram S, Uziely B, Cohen P, et al: Thrombin receptor overexpression in malignant and physiological invasion processes. Nat Med 4: 909-914, 1998.
    • (1998) Nat Med , vol.4 , pp. 909-914
    • Even-Ram, S.1    Uziely, B.2    Cohen, P.3
  • 26
    • 34547577319 scopus 로고    scopus 로고
    • p53 and its isoforms in cancer
    • Bourdon JC: p53 and its isoforms in cancer. Br J Cancer 97: 277-282, 2007.
    • (2007) Br J Cancer , vol.97 , pp. 277-282
    • Bourdon, J.C.1
  • 27
    • 0036781973 scopus 로고    scopus 로고
    • A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor
    • Suyama K, Shapiro I, Guttman M and Hazan RB: A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor. Cancer Cell 2: 301-314, 2002.
    • (2002) Cancer Cell , vol.2 , pp. 301-314
    • Suyama, K.1    Shapiro, I.2    Guttman, M.3    Hazan, R.B.4
  • 28
    • 27944452744 scopus 로고    scopus 로고
    • Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model
    • Xian W, Schwertfeger KL, Vargo-Gogola T and Rosen JM: Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol 171: 663-673, 2005.
    • (2005) J Cell Biol , vol.171 , pp. 663-673
    • Xian, W.1    Schwertfeger, K.L.2    Vargo-Gogola, T.3    Rosen, J.M.4
  • 29
    • 33845331706 scopus 로고    scopus 로고
    • FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas
    • Reis-Filho JS, Simpson PT, Turner NC, et al: FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res 12: 6652-6662, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 6652-6662
    • Reis-Filho, J.S.1    Simpson, P.T.2    Turner, N.C.3
  • 30
    • 34447325266 scopus 로고    scopus 로고
    • FGFR1 amplification in breast carcinomas: A chromogenic in situ hybridisation analysis
    • Elbauomy Elsheikh S, Green AR, Lambros MB, et al: FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis. Breast Cancer Res 9: R23, 2007.
    • (2007) Breast Cancer Res , vol.9
    • Elbauomy, E.S.1    Green, A.R.2    Lambros, M.B.3
  • 31
    • 18144413583 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling in tumourigenesis
    • Grose R and Dickson C: Fibroblast growth factor signaling in tumourigenesis. Cytokine Growth Factor Rev 16: 179-186, 2005.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 179-186
    • Grose, R.1    Dickson, C.2
  • 32
    • 0037141345 scopus 로고    scopus 로고
    • Intratumoural microvessel density in human solid tumours
    • Hasan J, Byers R and Jayson GC: Intratumoural microvessel density in human solid tumours. Br J Cancer 86: 1566-1577, 2002.
    • (2002) Br J Cancer , vol.86 , pp. 1566-1577
    • Hasan, J.1    Byers, R.2    Jayson, G.C.3
  • 33
    • 71049118533 scopus 로고    scopus 로고
    • Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles
    • Lopes N, Sousa B, Vieira D, et al: Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles. Histopathology 55: 594-599, 2009.
    • (2009) Histopathology , vol.55 , pp. 594-599
    • Lopes, N.1    Sousa, B.2    Vieira, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.