메뉴 건너뛰기




Volumn 4, Issue 1, 2012, Pages 67-74

Costs and outcomes associated with clopidogrel discontinuation in Medicare beneficiaries with acute coronary syndrome in the coverage gap

Author keywords

Acute coronary syndrome; Clopidogrel; Health resource utilization; Medicare

Indexed keywords

CLOPIDOGREL;

EID: 84864689231     PISSN: None     EISSN: 11791365     Source Type: Journal    
DOI: 10.2147/DHPS.S32473     Document Type: Article
Times cited : (5)

References (29)
  • 1
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2011 update: A report from the American Heart Association
    • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation. 2011;123(4):e18-e209.
    • (2011) Circulation. , vol.123 , Issue.4
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 2
    • 70349675844 scopus 로고    scopus 로고
    • Acute coronary syndromes: Morbidity, mortality, and pharmacoeconomic burden
    • Kolansky DM. Acute coronary syndromes: morbidity, mortality, and pharmacoeconomic burden. Am J Manag Care. 2009;15(Suppl 2):S36-S41.
    • (2009) Am J Manag Care. , vol.15 , Issue.SUPPL. 2
    • Kolansky, D.M.1
  • 3
    • 39749086265 scopus 로고    scopus 로고
    • One-year costs of ischemic heart disease among patients with acute coronary syndromes: Findings from a multi-employer claims database
    • Menzin J, Wygant G, Hauch O, Jackel K, Friedman M. One-year costs of ischemic heart disease among patients with acute coronary syndromes: findings from a multi-employer claims database. Curr Med Res Opin. 2008;24(2):461-468.
    • (2008) Curr Med Res Opin. , vol.24 , Issue.2 , pp. 461-468
    • Menzin, J.1    Wygant, G.2    Hauch, O.3    Jackel, K.4    Friedman, M.5
  • 4
    • 79955760903 scopus 로고    scopus 로고
    • 2011ACCF/AHA focused update incorporated into the ACC/AHA 2007guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines
    • Anderson JL, Adams CD, Antman EM, et al. 2011ACCF/AHA focused update incorporated into the ACC/AHA 2007guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2011;123(18):e426-e579.
    • (2011) Circulation. , vol.123 , Issue.18
    • Anderson, J.L.1    Adams, C.D.2    Antman, E.M.3
  • 5
    • 34548545280 scopus 로고    scopus 로고
    • ACC/AHA 2007guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction
    • A report of the American College of Cardiology/American Heart Association task force on practice guidelines (writing committee to revise the 2002guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction): Developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (writing committee to revise the 2002guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation. 2007;116(7):e148-e304.
    • (2007) Circulation. , vol.116 , Issue.7
    • Anderson, J.L.1    Adams, C.D.2    Antman, E.M.3
  • 6
    • 37849041229 scopus 로고    scopus 로고
    • 2007 focused update of the ACC/AHA 2004guidelines for the management of patients with ST-elevation myocardial infarction
    • A report of the American College of Cardiology/American Heart Association task force on practice guidelines
    • Antman EM, Hand M, Armstrong PW, et al. 2007 focused update of the ACC/AHA 2004guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. J Am Coll Cardiol. 2008;51(2):210-247.
    • (2008) J Am Coll Cardiol. , vol.51 , Issue.2 , pp. 210-247
    • Antman, E.M.1    Hand, M.2    Armstrong, P.W.3
  • 7
    • 70450199115 scopus 로고    scopus 로고
    • 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005guideline and 2007 focused update): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Kushner FG, Hand M, Smith SC Jr, et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2009;54(23):2205-2241.
    • (2009) J Am Coll Cardiol. , vol.54 , Issue.23 , pp. 2205-2241
    • Kushner, F.G.1    Hand, M.2    Smith Jr., S.C.3
  • 8
    • 84855992555 scopus 로고    scopus 로고
    • 2011ACCF/AHA/scai guideline for percutaneous coronary intervention. A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the Society for Cardiovascular Angiography and Interventions
    • Levine GN, Bates ER, Blankenship JC, et al. 2011ACCF/AHA/scai guideline for percutaneous coronary intervention. A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol. 2011;58(24):e44-e122.
    • (2011) J Am Coll Cardiol. , vol.58 , Issue.24
    • Levine, G.N.1    Bates, E.R.2    Blankenship, J.C.3
  • 9
    • 80054054702 scopus 로고    scopus 로고
    • Clopidogrel discontinuation after acute coronary syndromes: Frequency, predictors and associations with death and myocardial infarction-a hospital registry-primary care linked cohort (MINAP-GPRD)
    • Boggon R, van Staa TP, Timmis A, et al. Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction-a hospital registry-primary care linked cohort (MINAP-GPRD). Eur Heart J. 2011;32(19):2376-2386.
    • (2011) Eur Heart J. , vol.32 , Issue.19 , pp. 2376-2386
    • Boggon, R.1    van Staa, T.P.2    Timmis, A.3
  • 10
    • 79958264154 scopus 로고    scopus 로고
    • Effect of early clopidogrel discontinuation on rehospitalization in acute coronary syndrome: Results from two distinct patient populations
    • Ernst FR, Johnston S, Curkendall S, et al. Effect of early clopidogrel discontinuation on rehospitalization in acute coronary syndrome: results from two distinct patient populations. Am J Health Syst Pharm. 2011;68(11):1015-1024.
    • (2011) Am J Health Syst Pharm. , vol.68 , Issue.11 , pp. 1015-1024
    • Ernst, F.R.1    Johnston, S.2    Curkendall, S.3
  • 11
    • 80054053534 scopus 로고    scopus 로고
    • Systematic review of thienopyridine discontinuation and its impact upon clinical outcomes
    • Gaglia MA Jr, Waksman R. Systematic review of thienopyridine discontinuation and its impact upon clinical outcomes. Eur Heart J. 2011;32(19):2358-2364.
    • (2011) Eur Heart J. , vol.32 , Issue.19 , pp. 2358-2364
    • Gaglia Jr., M.A.1    Waksman, R.2
  • 12
    • 38949209538 scopus 로고    scopus 로고
    • Incidence of death and acute myocardial infarction associated with stopping clopidogrel after acute coronary syndrome
    • Ho PM, Peterson ED, Wang L, et al. Incidence of death and acute myocardial infarction associated with stopping clopidogrel after acute coronary syndrome. JAMA. 2008;299(5):532-539.
    • (2008) JAMA. , vol.299 , Issue.5 , pp. 532-539
    • Ho, P.M.1    Peterson, E.D.2    Wang, L.3
  • 13
    • 77953401971 scopus 로고    scopus 로고
    • Adverse events after stopping clopidogrel in post-acute coronary syndrome patients: Insights from a large integrated healthcare delivery system
    • Ho PM, Tsai TT, Wang TY, et al. Adverse events after stopping clopidogrel in post-acute coronary syndrome patients: insights from a large integrated healthcare delivery system. Circ Cardiovasc Qual Outcomes. 2010;3(3):303-308.
    • (2010) Circ Cardiovasc Qual Outcomes. , vol.3 , Issue.3 , pp. 303-308
    • Ho, P.M.1    Tsai, T.T.2    Wang, T.Y.3
  • 14
    • 33745960402 scopus 로고    scopus 로고
    • Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: Results from the PREMIER registry
    • Spertus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry. Circulation. 2006;113(24):2803-2809.
    • (2006) Circulation. , vol.113 , Issue.24 , pp. 2803-2809
    • Spertus, J.A.1    Kettelkamp, R.2    Vance, C.3
  • 15
    • 69849093564 scopus 로고    scopus 로고
    • Clinical impact of early clopidogrel discontinuation following acute myocardial infarction hospitalization or stent implantation: Analysis in a single integrated health network
    • Wiederkehr D, Berenson K, Casciano R, et al. Clinical impact of early clopidogrel discontinuation following acute myocardial infarction hospitalization or stent implantation: analysis in a single integrated health network. Curr Med Res Opin. 2009;25(9):2317-2325.
    • (2009) Curr Med Res Opin. , vol.25 , Issue.9 , pp. 2317-2325
    • Wiederkehr, D.1    Berenson, K.2    Casciano, R.3
  • 16
    • 33846828736 scopus 로고    scopus 로고
    • Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: A science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians
    • Grines CL, Bonow RO, Casey DE Jr, et al. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians. J Am Coll Cardiol. 2007;49(6):734-739.
    • (2007) J Am Coll Cardiol. , vol.49 , Issue.6 , pp. 734-739
    • Grines, C.L.1    Bonow, R.O.2    Casey Jr., D.E.3
  • 17
    • 60449109429 scopus 로고    scopus 로고
    • Barriers to clopidogrel adherence following placement of drug-eluting stents
    • Pallares MJ, Powers ER, Zwerner PL, et al. Barriers to clopidogrel adherence following placement of drug-eluting stents. Ann Pharmacother. 2009;43(2):259-267.
    • (2009) Ann Pharmacother. , vol.43 , Issue.2 , pp. 259-267
    • Pallares, M.J.1    Powers, E.R.2    Zwerner, P.L.3
  • 18
    • 84864691054 scopus 로고    scopus 로고
    • The Henry K. Kaiser Family Foundation. Available at: Accessed June 5, 2012
    • The Henry K. Kaiser Family Foundation. Medicare Part D 2011: the coverage gap. Available at: http://www.kff.org/medicare/upload/8222.pdf. Accessed June 5, 2012.
    • Medicare Part D 2011: The coverage gap
  • 19
    • 80052305537 scopus 로고    scopus 로고
    • Changes in drug utilization during a gap in insurance coverage: An examination of the Medicare Part D coverage gap
    • Polinski JM, Shrank WH, Huskamp HA, et al. Changes in drug utilization during a gap in insurance coverage: an examination of the Medicare Part D coverage gap. PLoS Med. 2011;8(8):e1001075.
    • (2011) PLoS Med. , vol.8 , Issue.8
    • Polinski, J.M.1    Shrank, W.H.2    Huskamp, H.A.3
  • 21
    • 78650960645 scopus 로고    scopus 로고
    • Part D coverage gap and adherence to diabetes medications
    • Gu Q, Zeng F, Patel BV, Tripoli LC. Part D coverage gap and adherence to diabetes medications. Am J Manag Care. 2010;16(12):911-918.
    • (2010) Am J Manag Care. , vol.16 , Issue.12 , pp. 911-918
    • Gu, Q.1    Zeng, F.2    Patel, B.V.3    Tripoli, L.C.4
  • 22
    • 67649662377 scopus 로고    scopus 로고
    • The effect of Medicare Part D on drug and medical spending
    • Zhang Y, Donohue JM, Lave JR, et al. The effect of Medicare Part D on drug and medical spending. N Engl J Med. 2009;361(1):52-61.
    • (2009) N Engl J Med. , vol.361 , Issue.1 , pp. 52-61
    • Zhang, Y.1    Donohue, J.M.2    Lave, J.R.3
  • 23
    • 66149190565 scopus 로고    scopus 로고
    • The effects of the coverage gap on drug spending: A closer look at Medicare Part D
    • Zhang Y, Donohue JM, Newhouse JP, Lave JR. The effects of the coverage gap on drug spending: a closer look at Medicare Part D. Health Aff (Millwood). 2009;28(2):w317-w325.
    • (2009) Health Aff (Millwood). , vol.28 , Issue.2
    • Zhang, Y.1    Donohue, J.M.2    Newhouse, J.P.3    Lave, J.R.4
  • 24
    • 78650812050 scopus 로고    scopus 로고
    • How the doughnut hole affects prescription fulfillment decisions involving cardiovascular medications for Medicare Part D enrollees
    • Hales JW, George S. How the doughnut hole affects prescription fulfillment decisions involving cardiovascular medications for Medicare Part D enrollees. Manag Care. 2010;19(12):36-44.
    • (2010) Manag Care. , vol.19 , Issue.12 , pp. 36-44
    • Hales, J.W.1    George, S.2
  • 26
    • 77955507986 scopus 로고    scopus 로고
    • The Henry K Kaiser Family Foundation. Available at: Accessed June 5, 2012
    • The Henry K Kaiser Family Foundation. The Medicare Part D coverage gap: costs and consequences in 2007. Available at: http://www.kff.org/medicare/upload/7811.pdf. Accessed June 5, 2012.
    • The Medicare Part D coverage gap: Costs and consequences in 2007
  • 27
    • 84864657788 scopus 로고    scopus 로고
    • The Healthcare Costs and Utilization Project
    • Available at: Accessed June 5, 2012
    • The Healthcare Costs and Utilization Project. Chronic condition indicator (CCI) for ICD-9-CM. Available at: http://www.hcup-us.ahrq.gov/toolssoftware/chronic/chronic.jsp. Accessed June 5, 2012.
    • Chronic condition indicator (CCI) for ICD-9-CM
  • 28
    • 84856983957 scopus 로고    scopus 로고
    • Comparing pre-gap and gap behaviors for Medicare beneficiaries in a Medicare managed care plan
    • Nair KV, Frech-Tamas F, Jan S, et al. Comparing pre-gap and gap behaviors for Medicare beneficiaries in a Medicare managed care plan. J Health Care Finance. 2011;38(2):38-53.
    • (2011) J Health Care Finance. , vol.38 , Issue.2 , pp. 38-53
    • Nair, K.V.1    Frech-Tamas, F.2    Jan, S.3
  • 29
    • 67651151333 scopus 로고    scopus 로고
    • Medicare Part D update-lessons learned and unfinished business
    • Neuman P, Cubanski J. Medicare Part D update-lessons learned and unfinished business. N Engl J Med. 2009;361(4):406-414.
    • (2009) N Engl J Med. , vol.361 , Issue.4 , pp. 406-414
    • Neuman, P.1    Cubanski, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.