Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway

Cellular and Molecular Neurobiology

Volumn 32, Issue 4, 2012, Pages 523-529

  Gao, Yonglin ^a   Dong, Chaohua ^b   Yin, Jungang ^a   Shen, Jingyu ^a   Tian, Jingwei ^a   Li, Chunmei ^a  

^a YANTAI UNIVERSITY   (China)

^b QINGDAO AGRICULTURAL UNIVERSITY   (China)

Author keywords

Apoptosis; Fucoidan; Neuroprotective effects; Oxidative stress; PC12 cells; Phosphatidylinositol 3 kinase (PI3K) Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; FUCOIDIN; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LINE; CELL STRAIN PC12; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME RELEASE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENTS; OXIDANTS; PC12 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

EID: 84864687801     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-011-9792-0     Document Type: Article

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