Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers

Nature Medicine

Volumn 18, Issue 8, 2012, Pages 1205-1207

  Fromy, Bérengère ^a,b   Lingueglia, Eric ^c,d,e   Sigaudo Roussel, Dominique ^a,b   Saumet, Jean Louis ^a,b   Lazdunski, Michel ^c,d  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b UNIVERSITÉ LYON 1   (France)

^c CNRS   (France)

^d INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^e Laboratory of Excellence Ion Channel Science and Therapeutics   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACID SENSING ION CHANNEL 3; AMILORIDE; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; DICLOFENAC; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ION CHANNEL; LACTIC ACID; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INNERVATION; CONTROLLED STUDY; DECUBITUS; DISEASE SEVERITY; ENDOTHELIUM; ENZYME SYNTHESIS; FEMALE; HYPEREMIA; ISCHEMIA; MALE; MOUSE; NONHUMAN; PRESSURE INDUCED VASODILATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSORY NERVE CELL; SKIN BLOOD FLOW; SMOOTH MUSCLE RELAXATION; STIMULATION; TISSUE OXYGENATION; TISSUE PERFUSION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ACID SENSING ION CHANNELS; ADULT; AMILORIDE; ANIMALS; CALCITONIN; CNIDARIAN VENOMS; DICLOFENAC; ENDOTHELIUM, VASCULAR; FEMALE; FINGERS; HUMANS; HYPEREMIA; ISCHEMIA; MALE; MECHANORECEPTORS; MICE; MICE, KNOCKOUT; PRESSURE; PRESSURE ULCER; PROTEIN PRECURSORS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SINGLE-BLIND METHOD; SKIN; VASODILATION; YOUNG ADULT;

MUS; RODENTIA;

EID: 84864671626     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2844     Document Type: Article

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