Prevalence and risk factors of pre-diabetes after renal transplantation: A single-centre cohort study in 200 consecutive patients

Nephrology Dialysis Transplantation

Volumn 27, Issue 8, 2012, Pages 3330-3337

  Tillmann, Frank Peter ^a   Quack, Ivo ^a   Schenk, Ana ^a   Grabensee, Bernd ^a   Rump, Lars C ^a   Hetzel, Gerd R ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

pre diabetes; PTDM; risk factors; transplantation

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCINEURIN INHIBITOR; CYCLOSPORIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID; TACROLIMUS; THIAZIDE DIURETIC AGENT;

ADULT; AGE; ARTICLE; BODY MASS; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DOSE RESPONSE; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PREDICTION; PREDICTIVE VALUE; PRESSURE MEASUREMENT; PREVALENCE; PRIORITY JOURNAL; PULSE PRESSURE; RISK ASSESSMENT; RISK FACTOR; SENSITIVITY AND SPECIFICITY; SYNDROME DELINEATION; SYSTOLIC BLOOD PRESSURE;

ADULT; AGE FACTORS; BLOOD GLUCOSE; COHORT STUDIES; FEMALE; GERMANY; GLUCOSE TOLERANCE TEST; GRAFT REJECTION; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOTENSION; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PREDIABETIC STATE; PREVALENCE; PROGNOSIS; RISK FACTORS;

EID: 84864628973     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs020     Document Type: Article

References (40)

1. Montori VM, Velosa JA, Basu A et al. Posttransplantation diabetes: a systematic review of the literature. Diabetes Care 2002; 25: 583-592.
2. Davidson J, Wilkinson A, Dantal J et al. New-onset diabetes after transplantation: 2003 International Consensus Guidelines. Transplantation 2003; 75: SS3-SS24.
3. Hjelmesaeth J, Hartmann A, Leivestad T et al. The impact of earlydiagnosed new-onset post-transplantation diabetes mellitus on survival and major cardiac events. Kidney Int 2006; 69: 588-595.
4. Shah T, Kasravi A, Huang E et al. Risk factors for development of new-onset diabetes mellitus after kidney transplantation. Transplantation 2006; 82: 1673-1676.
5. Moore R, Ravindran V, Baboolal K. The burden of new-onset diabetes mellitus after transplantation. Clin Transplant 2006; 20: 755-761.
6. Valderhaug TG, Hjelmesaeth J, Rollag H et al. Reduced incidence of new-onset posttransplantation diabetes mellitus during the last decade. Transplantation 2007; 84: 1125-1130.
7. Araki M, Flechner SM, Ismail HR et al. Posttransplant diabetes mellitus in kidney transplant recipients receiving calcineurin or mTOR inhibitor drugs. Transplantation 2006; 81: 335-341.
8. Numakura K, Satoh S, Tsuchiya N et al. Clinical and genetic risk factors for posttransplant diabetes mellitus in adult renal transplant recipients treated with tacrolimus. Transplantation 2005; 80: 1419-1424.
9. Joss N, Staatz CE, Thomson AH et al. Predictors of new onset diabetes after renal transplantation. Clin Transplant 2007; 21: 136-143.
10. Blake DR, Meigs J, Muller DC et al. Impaired glucose tolerance, but not impaired fasting glucose, is associated with increased levels of coronary heart disease risk factors. Diabetes 2004; 53: 2095-2100.
11. The Decode Study Group, on behalf of the European Diabetes Epidemiology Group. Glucose tolerance and cardiovascular mortality. Arch Intern Med 2001; 161: 397-405.
12. Cosio FG, Kudva Y, van der Velde M et al. New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantation. Kidney Int 2005; 67: 2415-2421.
13. Tutone VK, Mark PB, Revanur V et al. Random blood glucose measurement and survival in nondiabetic renal transplant recipients. Transplant Proc 2004; 36: 3006-3011.
14. Sharif A, Moore R, Baboolal K. Influence of lifestyle modification in renal transplant recipients with postprandial hyperglycemia. Transplantation 2008; 85: 353-358.
15. Task Force of the Declaration of Istanbul Group. The declaration of Istanbul on organ trafficking and transplant tourism. Nephrol Dial Transplant 2008; 23: 3375-3380.
16. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2007; 30 (Suppl 1): S42-S47.
17. The International Expert Committee. International expert committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 2009; 32: 1327-1334.
18. Mollar-Purchades MA, Malek-Marin T, Merino-Torres JF et al. Diabetes mellitus after kidney transplantation: role of the impaired fasting glucose in the outcome of kidney transplantation. J Endocrinol Invest 2009; 32: 263-266.
19. Hoban R, Gielda B, Temkit M et al. Utility of HbA1c in the detection of subclinical post renal transplant diabetes. Transplantation 2006; 15: 379-383.
20. Valderhaug TG, Jenssen T, Hartmann A et al. Fasting plasma glucose and glycosylated hemoglobin in the screening for diabetes mellitus after renal transplantation. Transplantation 2009; 88: 429-434.
21. Tillmann FP, Schenk A, Oels M et al. Prevalence of abnormal oral glucose tolerance testing (oGTT) in renal transplant recipients: a cross-sectional single centre trial in 200 patients. ASN Annual Meeting 2007, San Francisco, SA-PO 424..
22. Bergrem HA, Valderhaug TG, Hartmann A et al. Glucose tolerance before and after renal transplantation. Nephrol Dial Trans 2010; 25: 985-992.
23. Shah A, Kendall G, Demme RA et al. Home glucometer monitoring markedly improves diagnosis of post renal transplant diabetes mellitus in renal transplant recipients. Transplantation 2005; 80: 775-781.
24. Trovati M, Ponziani MC, Massucco P et al. Blood glucose preprandial baseline decreases from morning to evening in type 2 diabetes: role of fasting blood glucose and influence on post-prandial excursions. Eur J Clin Invest 2002; 32: 179-186.
25. Hur KY, Kim MS, Kim YS et al. Risk factors associated with the onset and progression of posttransplant diabetes in renal allograft recipients. Diabetes Care 2007; 30: 609-615.
26. Chan HW, Cheung CY, Liu Yl et al. Prevalence of abnormal glucose metabolism in Chinese renal transplant recipients: a single centre study. Nephrol Dial Transplant 2008; 23: 3337-3342.
27. Porrini E, Moreno JM, Osuna A et al. Prediabetes in patients receiving tacrolimus in the first year after kidney transplantation: a prospective and multicenter study. Transplantation 2008; 85: 1133-1138.
28. Porrini E, Delgado P, Alvarez A et al. The combined effect of pretransplant triglyceride levels and the type of calcineurin inhibitor in predicting the risk of new onset diabetes after renal transplantation. Nephrol Dial Transplant 2008; 23: 1429-1435.
29. Luan FL, Zhang H, Schaubel DE et al. Comparative risk of impaired glucose metabolism associated with cyclosporine versus tacrolimus in the late posttransplant period. Am J Transplant 2008; 8: 1871-1877.
30. The NAVIGATOR Study Group. Effect of valsartan on the incidence of diabetes and cardiovascular events. N Engl J Med 2010; 362: 1477-1490.
31. Kuypers DR, Claes K, Bammens B et al. Early clinical assessment of glucose metabolism in renal allograft recipients: diagnosis and prediction of post-transplant diabetes mellitus (PTDM). Nephrol Dial Transplant 2008; 23: 2033-2042.
32. Schneider HJ, Friedrich N, Klotsche J et al. The predictive value of different measures of obesity for incident cardiovascular events and mortality. J Clin Endocrinol Metab 2010; 95: 1777-1785.
33. Hornum M, Jørgensen KA, Hansen JM et al. New-onset diabetes mellitus after kidney transplantation in Denmark. Clin J Am Soc Nephrol 2010; 5: 709-716.
34. McNeill AM, Rosamond WD, Girman CJ et al. The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care 2005; 28: 385-390.
35. Winkelmayer W, Lorenz M, Kramar R et al. C-reactive protein and body mass index independently predict mortality in kidney transplant recipients. Am J Transplant 2004; 4: 1148-1154.
36. Guida B, Trio R, Laccetti R et al. Role of dietary intervention on metabolic abnormalities and nutritional status after renal transplantation. Nephrol Dial Transplant 2007; 22: 3304-3310.
37. Fabrizi F, Martin P, Dixit V et al. Post-transplant diabetes mellitus and HCV seropositive status after renal transplantation: metaanalysis of clinical studies. Am J Transplant 2005; 5: 2433-2440.
38. Leung Ki EL, Venetz JP, Meylan P et al. Cytomegalovirus infection and new-onset post-transplant diabetes mellitus. Clin Transplant 2008; 22: 245-249.
39. Becker B, Kronenberg F, Kielstein J et al. Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease. J Am Soc Nephrol 2005; 16: 1091-1098.
40. Walczak DA, Calvert D, Jarzembowski TM et al. Increased risk of post-transplant diabetes mellitus despite early steroid-discontinuation in Hispanic kidney transplant recipients. Clin Transplant 2005; 19: 527-531