Donor preconditioning with rabbit anti-rat thymocyte immunoglobulin ameliorates ischemia reperfusion injury in rat kidney transplantation

Transplant Immunology

Volumn 27, Issue 1, 2012, Pages 1-7

  Cicora, Federico ^a,b,c   Roberti, Javier ^d   Lausada, Natalia ^a   González, Pedro ^e   Guerrieri, Diego ^c,f   Stringa, Pablo ^a   Cicora, Paola ^c   Vásquez, Daniela ^c   González, Ivana ^c   Palti, Gustavo ^b   Intile, Dante ^c   Raimondi, Clemente ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^b HOSPITAL ALEMÁN   (Argentina)

^c Foundation for the Research   (Argentina)

^d UNIVERSIDAD DE BELGRANO   (Argentina)

^e Centro Científico y Tecnológico Consejo Nacional de Investigaciones Científicas y Técnicas   (Argentina)

^f UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Apoptosis; Donor preconditioning; Ischemia reperfusion injury; Kidney transplantation; Thymoglobulin

Indexed keywords

CASPASE 8; CASPASE 9; CREATININE; CXCL3 CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 23P19; INTERLEUKIN 6; KIDNEY INJURY MOLECULE 1; PROTEIN BCL 2; THYMOCYTE ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DONOR; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; TREATMENT RESPONSE; UPREGULATION; UREA BLOOD LEVEL;

ANIMALS; ANTILYMPHOCYTE SERUM; APOPTOSIS; CASPASE 8; CELL ADHESION MOLECULES; CREATININE; GENE EXPRESSION PROFILING; GENES, BCL-2; HEME OXYGENASE-1; INTERLEUKIN-6; INTERLEUKINS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; NECROSIS; RANDOM ALLOCATION; RATS; RATS, WISTAR; REPERFUSION INJURY; THYMOCYTES; TISSUE DONORS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; UREA;

EID: 84864550443     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2012.03.004     Document Type: Article

References (32)

1. Mehrabi A., Mood Zh.A., Sadeghi M., Schmied BM, Müller SA, Welsch T, et al. Thymoglobulin and ischemia reperfusion injury in kidney and liver transplantation. Nephrol Dial Transplant 2007, 22(Suppl. 8). viii54-viii60.
2. Boros P., Bromberg J.S. New cellular and molecular immune pathways in ischemia/reperfusion injury. Am J Transplant 2006, 6(4):652-658.
3. Sievert A. Leukocyte depletion as a mechanism for reducing neutrophil-mediated ischemic-reperfusion injury during transplantation. J Extra Corpor Technol 2003, 35(1):48-52.
4. Eum H.A., Lee S.M. Effect of Trolox on altered vasoregulatory gene expression in hepatic ischemia/reperfusion. Arch Pharm Res 2004, 27(2):225-231.
5. Martins P., Chandraker A., Tullius S. Modifying graft immunogenicity and immune response prior to transplantation: potential clinical applications of donor and graft treatment. Transp Int 2006, 19:351-359.
6. Schuurs T.A., Gerbens F., van der Hoeven J.A., Ottens PJ, Kooi KA, Leuvenink HG, et al. Distinct transcriptional changes in donor kidneys upon brain death induction in rats: insights in the processes of brain death. Am J Transplant 2004, 4(12):1972-1981.
7. Brasile L., Stubenitsky B., Booster M., Arenada D., Haisch C., Kootstra G. Transfection and transgene expression in a human kidney during ex vivo warm perfusion. Transplant Proc 2002, 34:2624.
8. Kuecuek O., Mantouvalou L., Klemz R., Kotsch K, Volk HD, Jonas S, et al. Significant reduction of proinflammatory cytokines by treatment of the brain-dead donor. Transplant Proc 2005, 37(1):387-388.
9. Pratschke J., Kofla G., Wilhelm M.J., Vergopoulos A, Laskowski I, Shaw GD, et al. Improvements in early behavior of rat kidney allografts after treatment of the brain-dead donor. Ann Surg 2001, 234(6):732-740.
10. Kotsch K., Ulrich F., Reutzel-Selke A., Pascher A, Faber W, Warnick P, et al. Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trial. Ann Surg 2008, 248(6):1042-1050.
11. Gottmann U., Brinkkoetter P.T., Hoeger S., Gutermann K, Coutinho QZM, Ruf T, et al. Atorvastatin donor pretreatment prevents ischemia/reperfusion injury in renal transplantation in rats: possible role for aldose-reductase inhibition. Transplantation 2007, 84(6):755-762.
12. Michallet M.C., Preville X., Flacher M., Fournel S., Genestier L., Revillard J.P. Functional antibodies to leukocyte adhesion molecules in antithymocyte globulins. Transplantation 2003, 75(5):657-662. Epub 2003/03/18.
13. Li S.Q., Liang L.J. Protective mechanism of l-arginine against liver ischemic-reperfusion injury in rats. Hepatobiliary Pancreat Dis 2003, 2(4):549-552.
14. Aiello S., Cassis P., Mister M., Solini S, Rocchetta F, Abbate M, et al. Rabbit anti-rat thymocyte immunoglobulin preserves renal function during ischemia/reperfusion injury in rat kidney transplantation. Transpl Int 2011, 24(8):829-838.
15. Caumartin Y., Stephen J., Deng J.P., Lian D, Lan Z, Liu W, et al. Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation. Kidney Int 2011, 79(10):1080-1089.
16. Patel N.S., Chatterjee P.K., Di Paola R., Mazzon E, Britti D, De Sarro A, et al. Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion. J Pharmacol Exp Ther 2005, 312(3):1170-1178.
17. Donnahoo K.K., Meldrum D.R., Shenkar R., Chung C.S., Abraham E., Harken A.H. Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney. J Urol 2000, 163(4):1328-1332.
18. Cicora F., Lausada N., Vasquez D.N., Cicora P, Zalazar G, Gonzalez P, et al. Sirolimus in kidney transplant donors and clinical and histologic improvement in recipients: rat model. Transplant Proc 2010, 42(1):365-370.
19. Bonventre J.V., Zuk A. Ischemic acute renal failure: an inflammatory disease?. Kidney Int 2004, 66(2):480-485. Epub 2004/07/16.
20. Land W.G. The role of postischemic reperfusion injury and other nonantigen-dependent inflammatory pathways in transplantation. Transplantation 2005, 79(5):505-514.
21. Lane BR. Molecular markers of kidney injury. Urol Oncol in press.
22. Harlan J.M., Winn R.K. Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy. Crit Care Med 2002, 30(5 Suppl.):S214-S219.
23. Yeung M.Y., McGrath M., Najafian N. The emerging role of the TIM molecules in transplantation. Am J Transplant 2011, 11(10):2012-2019.
24. Beiras-Fernandez A., Chappell D., Hammer C., Beiras A., Reichart B., Thein E. Impact of polyclonal anti-thymocyte globulins on the expression of adhesion and inflammation molecules after ischemia-reperfusion injury. Transpl Immunol 2009, 20(4):224-228.
25. Ozdemir B.H., Ozdemir F.N., Demirhan B., Haberal M TGF-[beta]1 expression in renal allograft rejection and closporine A toxicity. Transplant 2005, 80(12):1681-1685.
26. Ouyang W., Kolls J.K., Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 2008, 28(4):454-467.
27. Manel N., Unutmaz D., Littman D.R. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008, 9(6):641-649.
28. Li M.O., Wan Y.Y., Sanjabi S., Robertson A.K., Flavell R.A. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 2006, 24:99-146.
29. Guan Q., Nguan C.Y., Du C. Expression of transforming growth factor-beta1 limits renal ischemia-reperfusion injury. Transplantation 2010, 89(11):1320-1327.
30. Womer K.L., Peng R., Patton P.R., Murawski M.R., Bucci M., Kaleem A., et al. The effects of renal transplantation on peripheral blood dendritic cells. Clin Transplant 2005, 19:659-667.
31. Nelson J.N., Rees A.J., Griffin M.D., Hughes J., Kurts C., Duffield J. The renal mononuclear phagocytic system. J Am Soc Nephrol 2012, 2012(23):194-203.
32. Tadagavadi R.K., Reeves W.B. Renal dendritic cells ameliorate nephrotoxic acute kidney injury. J Am Soc Nephrol 2010, 21:53-63.